Engineering a spleen-selective mRNA-LNPs vaccine by decoupling the inflammation from cellular immunity mediated cancer immunotherapy
Xiaoke Gao, Meng Zhang, Shiyang Du, Lixia Ma, Xiaohan Yao, Boao Xie, Jiajia Wan, Yuqiao Sheng, Bo Qin, Wenjing Deng, Ningjing Lei, Wentao Mo, Ming Wang, Zhijun Sun, Zhihai Qin, Fazhan Wang
Theranostics 2025; doi:10.7150/thno.118976; in press
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Single-shot multiparametric MRI for correcting T2-related bias in dynamic glucose-enhanced imaging
Junxian Jin, Haizhen Ding, Zhekai Chen, Yuan Huang, Hongmin Chen, Zhong Chen, Lin Chen
Theranostics 2025; doi:10.7150/thno.116483; accepted
Author manuscript

Development of a potent and safe CD137 agonist
Kang Yi Lee, Heng Sun, Yu Mei, Emily Nickles, Clemence Wei Xia Lai, Sashigala Ponnalagu, Mukul Prasad, Xiaoyuan Chen, Haiyan Liu, Herbert Schwarz
Theranostics 2025; doi:10.7150/thno.116136; accepted
Author manuscript

Machine Learning-Enhanced Confocal Raman Imaging Enables Label-Free Diagnosis and Spatial Metabolic Profiling of Isoniazid-Induced Hepatotoxicity
Shimei Wang, Xiaoren Wang, Xudong Cui, Xiaotong Xie, Zhu Zhu, Tomii Ayaka, Renxing Song, Liping Zhou, Jin Sun, Li Zhang, Ruisheng Ge, Lei Yu, Yang Li
Theranostics 2025; doi:10.7150/thno.119785; in press
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Biofilm-Disrupting Heterojunction Microneedles: Dual ROS Amplification and Glucose Deprivation for Accelerated Diabetic Wound Healin
Wenjie You, Feng Xiao, Zichao Cai, Jiaxin Zhao, Zhengyao Zhang, Weikang Hu, Yun Chen, Kwang Leong Choy, and Zijian Wang
Theranostics 2025; doi:10.7150/thno.120787; accepted
Author manuscript

GM-CSF+ Th: a central player in autoimmunity
Sha-Sha Fan, Xuan Xu, Yu-Bin Luo, Xiang-Yu Meng, Yi Liu
Theranostics 2025; doi:10.7150/thno.121766; accepted
Author manuscript

Luminal Stem-like Cells in High-risk/Locally Advanced Prostate Cancer Promote Resistance to Hormonal Therapy
Guyu Tang, Jing Liu, Xiaomei Gao, Kai Yuan, Minfeng Chen, Long Wang, Lin Qi, Yi Cai
Theranostics 2025; doi:10.7150/thno.112496; in press
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Naturally derived hydrogel with antioxidant, angiogenesis and photothermal effect to accelerate infected diabetic wound healing and reduce scar formation
Mengyu Yang, Pengyuan Liu, Pei Cheng, Chenghao Li, Jingmei Liu, Haifeng Sun, Fangxia Guan, Minghao Yao
Theranostics 2025; doi:10.7150/thno.117179; in press
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Integrative Spatially Resolved Proteomic and Metabolomic Imaging Reveals Synovitis Endotypes Implicated in Osteoarthritis Progression
Lin Zhu, Xin Diao, Chenrui Yuan, Chun Man Lawrence Lau, Jianing Wang, Wenlong Wu, Ali Mobasheri, Xavier Houard, Chunyi Wen, Zongwei Cai
Theranostics 2025; doi:10.7150/thno.117788; accepted
Author manuscript

The pathophysiology of mixed Alzheimer’s disease and vascular dementia
Mutaz Sarhan, Christian Wohlfeld, Ariel Perry-Mills, Jeffrey Meyers, James Fadel, E. Angela Murphy, Leonardo Bonilha, and Daping Fan
Theranostics 2025; doi:10.7150/thno.118737; accepted
Author manuscript

Single-Cell RNA Sequencing Technology Revealed Endothelial Cell Heterogeneity and Sox18-mediated EndMT in Abdominal Aortic Aneurysm
Xianxian Wu, Xuanyu Liu, Yuanzhi Cheng, Yuhan Zhang, Dou Shi, Yang Shi, Xing Liu, Jianghao Feng, Anxiong Long, Wei Hu, Zhiwei Yang
Theranostics 2025; doi:10.7150/thno.110254; in press
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Dissecting Tertiary Lymphoid Structures in Cancer: Maturation, Localization, and Density
Guang-Liang Su, Meng-Jie Zhang, Hao Li, Zhi-Jun Sun
Theranostics 2025; doi:10.7150/thno.113940; in press
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Neutrophil-Based Delivery Platforms: From Natural Mechanisms to Engineered Therapeutics
Yinggang Li, Xue Zhang, Yunkun Li, Ling Sun, Na Hu, Su Lui, Zhenyu Duan, Qiyong Gong, Kui Luo
Theranostics 2025; doi:10.7150/thno.117363; accepted
Author manuscript

Transcriptomic Profiling of the Tumor Immune Microenvironment Reveals Prognostic Markers in mCRPC Patients Treated with LuPSMA Therapy
Analena Handke, Leonor Lopes, Claudia Kesch, Christopher Darr, Elai Davicioni, Kuangyu Shi, Tugce Telli, Wolfgang P. Fendler, Ken Herrmann, Katharina Lückerath, Boris Hadaschik, Robert Seifert
Theranostics 2025; doi:10.7150/thno.113614; in press
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Super-Resolution Ultrasound Imaging of Vascular Dynamics to Monitor Focused Ultrasound Blood-Brain Barrier Opening
Sua Bae, Stephen A. Lee, Seongyeon Kim, Fotios Tsitsos, Yangpei Liu, and Elisa E. Konofagou
Theranostics 2025; doi:10.7150/thno.98098; accepted
Author manuscript

MR molecular imaging for monitoring and predicting tumor responses to immunotherapy in pancreatic cancer
Victoria E. A. Laney, Walter Zhao, Inga Hwang, Emma Hampson, Juan Dong, Ryan C. Hall, Kristin Weber-Bonk, Xueer Yuan, Elizabeth Delaney, Hannah Gilmore, Ruth Keri, Jordan Winter, Li Lily Wang and Zheng-Rong Lu
Theranostics 2025; doi:10.7150/thno.106481; accepted
Author manuscript