Online advance articles

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The “ART” of Epigenetics in Melanoma: From histone “Alterations, to Resistance and Therapies”
Thomas Strub, Robert Ballotti and Corine Bertolotto
Theranostics 2019; doi:10.7150/thno.36218; accepted
[Author manuscript]

Label-free whole-colony imaging and metabolic analysis of metastatic pancreatic cancer by an autoregulating flexible optical system
Binglin Shen, Junshuai Yan, Shiqi Wang, Feifan Zhou, Yihua Zhao, Rui Hu, Junle Qu, Liwei Liu
Theranostics 2019; doi:10.7150/thno.40869; accepted
[Author manuscript]

Spatial heterogeneity of nanomedicine investigated by multiscale imaging of the drug, the nanoparticle and the tumour environment
Josanne S. de Maar, Alexandros Marios Sofias, Tiffany Porta Siegel, Rob J. Vreeken, Chrit Moonen, Clemens Bos, Roel Deckers
Theranostics 2019; doi:10.7150/thno.38625; accepted
[Author manuscript]

Nanoparticle-based cell trackers for biomedical applications
Jen-Shyang Ni, Yaxi Li, Wentong Yue, Bin Liu, Kai Li
Theranostics 2019; doi:10.7150/thno.39915; accepted
[Author manuscript]

The Effect of Cardiogenic Factors on Cardiac Mesenchymal Cell Anti-Fibrogenic Paracrine Signaling and Therapeutic Performance
Justin Scott Heidel, Annalara Garland Fischer, Xian-Liang Tang, Ghazal Sadri, Wen-Jian Wu, Claudiu Romolus Moisa, Heather Stowers, Neel Sandella, Marcin Wysoczynski, Shizuka Uchida, Joseph Brady Moore IV
Theranostics 2019; doi:10.7150/thno.41000; accepted
[Author manuscript]

Re-recognition of pseudogenes: From molecular to clinical applications
Xu Chen, Lin Wan, Wei Wang, Wen-Jin Xi, An-Gang Yang and Tao Wang
Theranostics 2019; doi:10.7150/thno.40659; accepted
[Author manuscript]

ROS-responsive nano-drug delivery system combining mitochondria-targeting Ceria nanoparticles with atorvastatin for acute kidney injury
Hui Yu, Feiyang Jin, Di Liu, Gaofeng Shu, Xiaojuan Wang, Jing Qi, Mingchen Sun, Ping Yang, Saiping Jiang, Xiaoying Ying, Yongzhong Du, ∗
Theranostics 2019; doi:10.7150/thno.40395; accepted
[Author manuscript]

Sex Differences Revealed in a Mouse CFA Inflammation Model with Macrophage Targeted Nanotheranostics
Lu Liu, Huseyin Karagoz, Michele Herneisey, Fatih Zor, Takaaki Komatsu, Shannon Loftus, Bratislav M. Janjic, Vijay S. Gorantla, Jelena M. Janjic
Theranostics 2019; doi:10.7150/thno.41309; accepted
[Author manuscript]

Monitoring innate immune cell dynamics in the glioma microenvironment by correlated magnetic resonance imaging and multiphoton microscopy (MR-MPM)
Kianush Karimian-Jazi, Philipp Munch, Allen Alexander, Manuel Fischer, Manuel Piechutta, Matthia A. Karreman, Gergely M. Solecki, Anna S. Berghoff, Kira Pfleiderer, Mirco Friedrich, Katrin Deumelandt, Felix T. Kurz, Wolfgang Wick, Sabine Heiland, Martin Bendszus, Frank Winkler, Michael Platten, and Michael O. Breckwoldt, ♯
Theranostics 2019; doi:10.7150/thno.38659; accepted
[Author manuscript]

Real-time colorectal cancer diagnosis using PR-OCT with deep learning
Yifeng Zeng, †, Shiqi Xu, †, William C. Chapman Jr, Shuying Li, Zahra Alipour, Heba Abdelal, Deyali Chatterjee, Matthew Mutch, and Quing Zhu
Theranostics 2019; doi:10.7150/thno.40099; accepted
[Author manuscript]

Development of a new class of PSMA radioligands comprising ibuprofen as an albumin-binding entity
Luisa M. Deberle, Martina Benešová, Christoph A. Umbricht, Francesca Borgna, Manuel Büchler, Konstantin Zhernosekov, Roger Schibli, Cristina Müller
Theranostics 2019; doi:10.7150/thno.40482; accepted
[Author manuscript]

Sustained release of dermal papilla–derived exosomes from injectable microgel promotes hair growth
Yuxin Chen, Junfei Huang, Ruosi Chen, Lunan Yang, Jin Wang, Bingcheng Liu, Lijuan Du, Yanhua Yi, James Jia, Yanwei Xu, Qian Chen, Djakaya Guydidier Ngondi, Yong Miao and Zhiqi Hu
Theranostics 2019; doi:10.7150/thno.39566; in press
[Author manuscript]

Development of a high affinity Anticalin® directed against human CD98hc for theranostic applications
Friedrich-Christian Deuschle, Volker Morath, André Schiefner, Corinna Brandt, Simone Ballke, Sybille Reder, Katja Steiger, Markus Schwaiger, Wolfgang Weber, Arne Skerra
Theranostics 2019; doi:10.7150/thno.38968; accepted
[Author manuscript]

Chimeric peptide supramolecular nanoparticles for plectin-1 targeted miRNA-9 delivery in pancreatic cancer
Ying Wu, Yuexiao Tang, Shangzhi Xie, Xiaoxiao Zheng, Shufen Zhang, Jiayan Mao, Baoming Wang, Yuerou Hou, Liqiang Hu, Kequn Chai and Wei Chen
Theranostics 2019; doi:10.7150/thno.38327; in press
[Author manuscript]

CBP mediated DOT1L acetylation confers DOT1L stability and promotes cancer metastasis
Chaohua Liu, Qiaoyan Yang, Qian Zhu, Xiaopeng Lu, Meiting Li, Tianyun Hou, Zhiming Li, Ming Tang, Yinglu Li, Hui Wang, Yang Yang, Haiying Wang, Ying Zhao, He Wen, Xiangyu Liu, Zebing Mao, and Wei-Guo Zhu
Theranostics 2019; doi:10.7150/thno.39013; in press
[Author manuscript]

The Roles of GSK-3β in Regulation of Retinoid Signaling and Sorafenib Treatment Response in Hepatocellular Carcinoma
Shuaishuai Zhang, Weiwei Gao, Juan Tang, Huaifang Zhang, Yuqi Zhou, Jie Liu, Kun Chen, Fangzhou Liu, Wengang Li, Sally K. Y. To, Alice Sze Tsai Wong, Xiao-kun Zhang, Hu Zhou, Jin-Zhang Zeng
Theranostics 2019; doi:10.7150/thno.38711; in press
[Author manuscript]

The Influence of Glycans-Specific Bioconjugation on the FcγRI Binding and In Vivo Performance of 89Zr-DFO-Pertuzumab
Delphine Vivier, Kimberly Fung, Cindy Rodriguez, Pierre Adumeau, Gary A. Ulaner, Jason S. Lewis, Sai Kiran Sharma, Brian M. Zeglis
Theranostics 2019; doi:10.7150/thno.39089; in press
[Author manuscript]

Investigating the effects of dexamethasone on blood-brain barrier permeability and inflammatory response following focused ultrasound and microbubble exposure
Dallan McMahon, Wendy Oakden, Kullervo Hynynen
Theranostics 2019; doi:10.7150/thno.40908; in press
[Author manuscript]

Nanocarrier-based drug combination therapy for glioblastoma
Mengnan Zhao, Demian van Straten, Marike L.D. Broekman, Véronique Préat, Raymond M. Schiffelers
Theranostics 2019; doi:10.7150/thno.38147; accepted
[Author manuscript]

Glucose Oxidase-Instructed Traceable Self-Oxygenation/Hyperthermia Dually Enhanced Cancer Starvation Therapy
Ting Hea, b‡, Han Xua‡, Yifan Zhang, a Shijian Yi, c Run Cui, a Shaojun Xing, a Chaoliang Wei, a Jing Lin, a Peng Huanga
Theranostics 2019; doi:10.7150/thno.40439; in press
[Author manuscript]

PTPN13 induces cell junction stabilization and inhibits mammary tumor invasiveness
Mohamed Hamyeh, Florence Bernex, Romain M. Larive, Aurélien Naldi, Serge Urbach, Joelle Simony-Lafontaine, Carole Puech, William Bakhache, Jérome Solassol, Peter J. Coopman, Wiljan J.A.J Hendriks and Gilles Freiss
Theranostics 2019; doi:10.7150/thno.38537; accepted
[Author manuscript]

Promotion of mitochondrial fusion protects against developmental PBDE-47 neurotoxicity by restoring mitochondrial homeostasis and suppressing excessive apoptosis
Lixin Dong, Pei Li, Kaichao Yang, Luming Liu, Hui Gao, Guoyu Zhou, Qian Zhao, Tao Xia, Aiguo Wang, Shun Zhang
Theranostics 2019; doi:10.7150/thno.40060; accepted
[Author manuscript]

Proteomic analysis of intracellular protein corona of nanoparticles elucidates nano-trafficking network and nano-bio interactions
Mengmeng Qin, Jian Zhang, Minghui Li, Dan Yang, Dechun Liu, Siyang Song, Jijun Fu, Hua Zhang, Wenbing Dai, Xueqing Wang, Yiguang Wang, Bing He and Qiang Zhang
Theranostics 2019; doi:10.7150/thno.38900; accepted
[Author manuscript]

Nanobody-based CD38-specific heavy chain antibodies induce killing of multiple myeloma and other hematological malignancies
Levin Schriewer, Kerstin Schütze, Katharina Petry, Julia Hambach, William Fumey, Julia Koenigsdorf, Natalie Baum, Stephan Menzel, Björn Rissiek, Kristoffer Riecken, Boris Fehse, Jana Larissa Röckendorf, Joanna Schmid, Birte Albrecht, Hans Pinnschmidt, Francis Ayuk, Nicolaus Kröger, Mascha Binder, Gunter Schuch, Timon Hansen, Friedrich Haag, Gerhard Adam, Friedrich Koch-Nolte, Peter Bannas
Theranostics 2019; doi:10.7150/thno.38533; accepted
[Author manuscript]

Near-IR emissive rare-earth nanoparticles for guided surgery
Zhibei Qu, Jianlei Shen, Qian Li, Feng Xu, Fei Wang, Xueli Zhang, Chunhai Fan
Theranostics 2019; doi:10.7150/thno.40808; accepted
[Author manuscript]

Nanoscintillator-Mediated X-Ray Induced Photodynamic Therapy for Deep-Seated Tumors: from Concept to Biomedical Applications
Wenjing Sun, Zijian Zhou, Guillem Pratx, Xiaoyuan Chen, Hongmin Chen
Theranostics 2019; doi:10.7150/thno.41578; in press
[Author manuscript]

Coating biomimetic nanoparticles with chimeric antigen receptor T cell-membrane provides high specificity for hepatocellular carcinoma photothermal therapy treatment
Weijie Ma, Daoming Zhu, Jinghua Li, Xi Chen, Wei Xie, Xiang Jiang, Long Wu, Ganggang Wang, Yusha Xiao, Zhisu Liu, Fubing Wang, Andrew Li, Dan Shao, Wenfei Dong, Wei Liu, Yufeng Yuan
Theranostics 2019; doi:10.7150/thno.40291; in press
[Author manuscript]

Smooth muscle SIRT1 reprograms endothelial cells to suppress angiogenesis after ischemia
Yong-Qing Dou; Peng Kong; Chang-Lin Li; Hong-Xing Sun; Wei-Wei Li; Yuan Yu; Lei Nie; Li-Li Zhao; Sui-Bing Miao; Xiao-Kun Li; Chen Dong; Jin-Wen Zhang; Yang Liu; Xiao-Xia Huo; Kui Chi; Xiang Gao; Ning Zhang; Lin Weng; Hongyuan Yang; Fan Zhang; Mei Han
Theranostics 2019; doi:10.7150/thno.39320; in press
[Author manuscript]

Nerve growth factor activates autophagy in Schwann cells to enhance myelin debris clearance and to expedite nerve regeneration
Rui Li, Duohui Li, Chengbiao Wu, Libing Ye, Yanqing Wu, Yuan Yuan, Shengnan Yang, Ling Xie, Yuqin Mao, Ting Jiang, Yiyang Li, Jian Wang, Hongyu Zhang, Xiaokun Li, Jian Xiao
Theranostics 2019; doi:10.7150/thno.40919; in press
[Author manuscript]

Lipid oversupply induces CD36 sarcolemmal translocation via dual modulation of PKCζ and TBC1D1: an early event prior to insulin resistance
Bili Zhu, Ming-Yue Li, Quanming Lin, Zhicheng Liang, Qihang Xin, Menghuan Wang, Zhendan He, Xiaomei Wang, Xuli Wu, George G. Chen, Peter CY Tong, Weizhen Zhang, Li-Zhong Liu
Theranostics 2019; doi:10.7150/thno.40021; in press
[Author manuscript]

Deubiquitinase USP28 inhibits ubiquitin ligase KLHL2-mediated uridine-cytidine kinase 1 degradation and confers sensitivity to 5’-azacytidine-resistant human leukemia cells
Heng Zhang, He Huang, Xing Feng, Huiwen Song, Zhiyong Zhang, Aizong Shen, Xingfeng Qiu
Theranostics 2019; doi:10.7150/thno.36503; in press
[Author manuscript]

Nanocarrier-mediated antioxidant delivery for liver diseases
Senlin Li, Huiru Li, Xiaoding Xu, Phei Er Saw, Lei Zhang
Theranostics 2019; doi:10.7150/thno.38834; in press
[Author manuscript]

A bioceramic scaffold composed of strontium-doped three-dimensional hydroxyapatite whiskers for enhanced bone regeneration in osteoporotic defects
Rui Zhao, Siyu Chen, Wanlu Zhao, Long Yang, Bo Yuan, Voicu Stefan Ioan, Antoniac Vasile Iuli-an, Xiao Yang, Xiangdong Zhu, Xingdong Zhang
Theranostics 2019; doi:10.7150/thno.40103; accepted
[Author manuscript]

A mouse model of MSU-induced acute inflammation in vivo highlights imiquimod-dependent targeting of Il-1 as relevant therapy for gout patients
Alexandre Mariotte; Aurore De Cauwer; Chrystelle Po; Chérine Abou-Faycal; Angélique Pichot; Nicodème Paul; Ismael Aouadi; Raphael Carapito; Benoit Frisch; Cécile Macquin; Emmanuel Chatelus; Jean Sibilia1; Jean-Paul Armspach; Seiamak Bahram; Philippe Georgel
Theranostics 2019; doi:10.7150/thno.40650; accepted
[Author manuscript]

Selective Intratumoral Drug Release and Simultaneous Inhibition of Oxidative Stress by a Highly Reductive Nanosystem and Its Application as an Anti-tumor Agent
Chunqi Zhu, Lihua Luo, Xindong jiang, Mengshi Jiang, Zhenyu Luo, Xiang Li, Weigen Qiu, Zhaolei Jin, Tianxiang Shen, Chunlong Li, Qingpo Li, Yunqing Qiu, and Jian You
Theranostics 2019; doi:10.7150/thno.38627; in press
[Author manuscript]

Modulating the cobalt dose range to manipulate multisystem cooperation in bone environment: a strategy to resolve the controversies about cobalt use for orthopedic applications
Guanqi Liu, Xiaoshuang Wang, Xuan Zhou, Linjun Zhang, Jiaomei Mi, Zhengjie Shan, Baoxin Huang, Zhuofan Chen, Zetao Chen
Theranostics 2019; doi:10.7150/thno.37931; in press
[Author manuscript]

Cardiorenal Exosomes Regulate Proangiogenic Paracrine of Adipose Mesenchymal Stem Cells after Myocardial Infarction
Lei Gao, Shuya Mei, Shuning Zhang, Qing Qin, Hao Li, Yiteng Liao, Huimin Fan, Zhongmin Liu, Hongming Zhu
Theranostics 2019; doi:10.7150/thno.37678; in press
[Author manuscript]

Response to mTOR and PI3K inhibitors in enzalutamide-resistant Luminal Androgen Receptor triple-negative breast cancer patient-derived xenografts
Florence Coussy, Marion Lavigne, Leanne de Koning, Rania El Botty, Fariba Nemati, Adnan Naguez, Guillaume Bataillon, Berengère Ouine, Ahmed Dahmani, Elodie Montaudon, Pierre Painsec, Sophie Chateau-Joubert, Fuhrmann Laetitia, Thibaut Larcher, Sophie Vacher, Walid Chemlali, Adrien Briaux, Samia Melaabi, Anne Vincent Salomon, Jean Marc Guinebretiere, Ivan Bieche, Elisabet
Theranostics 2019; doi:10.7150/thno.36182; in press
[Author manuscript]

Amplification-driven BCL6-suppressed cytostasis is mediated by transrepression of FOXO3 and post-translational modifications of FOXO3 in urinary bladder urothelial carcinoma
Wen-Ren Wu, Jen-Tai Lin, Cheng-Tang Pan, Ti-Chun Chan, Chen-Liang Liu, Wen-Jeng Wu, Jim Jinn-Chyuan Sheu, Bi-Wen Yeh, Steven K. Huang, Jheng-Yan Jhung, Meng-Shin Hsiao, Chien-Feng Li, Yow-Ling Shiue
Theranostics 2019; doi:10.7150/thno.39018; in press
[Author manuscript]

High-resolution 3D visualisation of nanomedicine distribution in tumours
Jennifer I. Moss, Hervé Barjat, Sally-Ann Emmas, Nicole Strittmatter, Juliana Maynard, Richard J. A. Goodwin, Gert Storm, Twan Lammers, Sanyogitta Puri, Marianne B. Ashford, and Simon T. Barry
Theranostics 2019; doi:10.7150/thno.37178; in press
[Author manuscript]

Synthesis and applications of theranostic oligonucleotides carrying multiple fluorine atoms
Valeriy G. Metelev, Alexei A. Bogdanov, Jr
Theranostics 2019; doi:10.7150/thno.37936; in press
[Author manuscript]

Fructose-1,6-bisphosphatase loss modulates STAT3-dependent expression of PD-L1 and cancer immunity
Bo Wang, Yingke Zhou, Jun Zhang, Xin Jin, Heshui Wu and Haojie Huang
Theranostics 2019; doi:10.7150/thno.38137; in press
[Author manuscript]

Refining Cancer Management Using Integrated Liquid Biopsy
Juhui Qiua, Jianxiong Xua, Kang Zhanga, Wei Gua, Liming Nieb, Guixue Wanga, Yang Luoacd
Theranostics 2019; doi:10.7150/thno.40677; accepted
[Author manuscript]

Theranostic Nanobubble Encapsulating a Plasmon-Enhanced Upconversion Hybrid Nanosystem for Cancer Therapy
Wen-Tse Huang‡, Ming-Hsien Chan‡, Xueyuan Chen, Michael Hsiao, and Ru-Shi Liu
Theranostics 2019; doi:10.7150/thno.38684; in press
[Author manuscript]

Therapeutic targeting of YY1/MZF1 axis by MZF1-uPEP inhibits aerobic glycolysis and neuroblastoma progression
Erhu Fang, Xiaojing Wang, Jianqun Wang, Anpei Hu, Huajie Song, Feng Yang, Dan Li, Wenjing Xiao, Yajun Chen, Yanhua Guo, Yang Liu, Hongjun Li, Kai Huang, Liduan Zheng, Qiangsong Tong
Theranostics 2019; doi:10.7150/thno.37383; accepted
[Author manuscript]

EPR-mediated tumor targeting using ultrasmall-hybrid nanoparticles: From animal to human with theranostic AGuIX nanoparticles
Guillaume Bort, François Lux, Sandrine Dufort, Yannick Crémillieux, Camille Verry, Olivier Tillement
Theranostics 2019; doi:10.7150/thno.37543; accepted
[Author manuscript]

68-Gallium-PSMA-HBED-CC PET/CT imaging for adenoid cystic carcinoma and salivary duct carcinoma: a phase 2 imaging study
Wim van Boxtel, Susanne Lütje, Ilse C.H. van Engen-van Grunsven, Gerald W. Verhaegh, Jack A. Schalken, Marianne A. Jonker, James Nagarajah, Martin Gotthardt, Carla M.L. van Herpen
Theranostics 2019; doi:10.7150/thno.38501; in press
[Author manuscript]

Mesenchymal stem cell-loaded thermosensitive hydroxypropyl chitin hydrogel combined with a three-dimensional-printed poly(ε-caprolactone) /nano-hydroxyapatite scaffold to repair bone defects via osteogenesis, angiogenesis and immunomodulation
Xiongfa Ji, Yuan Xi, Limin Ma, Bo Bi, Hao Zhu, Zehua lei, Wenbin Liu, HongXu Pu, Jiawei Jiang, Xulin Jiang, Yu Zhang, Jun Xiao
Theranostics 2019; doi:10.7150/thno.39167; in press
[Author manuscript]

Biomineralized Bimetallic Oxide Nanotheranostics for Multimodal Imaging-Guided Combination Therapy
Jianrong Wu, Gareth R. Williams, Shiwei Niu, Yanbo Yang, Xuejing Zhang, Li-Min Zhu
Theranostics 2019; doi:10.7150/thno.40715; in press
[Author manuscript]

Allosteric regulation of protein 14-3-3ζ scaffold by small-molecule editing modulates histone H3 post-translational modifications
Yan-Jun Wan, Li-Xi Liao, Yang Liu, Heng Yang, Xiao-Min Song, Li-Chao Wang, Xiao-Wen Zhang, Yi Qian, Dan Liu, Xiao-Meng Shi, Li-Wen Han, Qing Xia, Ke-Chun Liu, Zhi-Yong Du, Yong Jiang, Ming-Bo Zhao, Ke-Wu Zeng, Peng-Fei Tu
Theranostics 2019; doi:10.7150/thno.38483; in press
[Author manuscript]

Targeted destruction of cancer stem cells using multifunctional magnetic nanoparticles that enable combined hyperthermia and chemotherapy
Dandan Liu, Yingcai Hong, Yaping Li, Chong Hu, Tak-Chun Yip, Wai-Kin Yu, Yu Zhu, Chi-Chun Fong, Weimao Wang, Siu-Kie Au, Shubin, Wang, Mengsu Yang
Theranostics 2019; doi:10.7150/thno.38989; in press
[Author manuscript]

A sericin/ graphene oxide composite scaffold as a biomimetic extracellular matrix for structural and functional repair of calvarial bone
Chao Qi, Yan Deng, Luming Xu, Cheng Yang, Yuanyuan Zhu, Guobin Wang, Zheng Wang, Lin Wang
Theranostics 2019; doi:10.7150/thno.39502; in press
[Author manuscript]

Polymerase chain reaction – surface-enhanced Raman spectroscopy (PCR-SERS) method for gene methylation level detection in plasma
Xiaozhou Li, Tianyue Yang, Caesar Siqi Li, Youtao Song, Deli Wang, Lili Jin, Hong Lou, Wei Li
Theranostics 2019; doi:10.7150/thno.30204; in press
[Author manuscript]

High Loading of Hydrophobic and Hydrophilic Agents via Small Immunostimulatory Carrier for Enhanced Tumor Penetration and Combinational Therapy
Jingjing Sun, Yichao Chen, Jieni Xu, Xiangping Song, Zhuoya Wan, Yuqian Du, Weina Ma, Xizhen Li, Lin Zhang, Song Li
Theranostics 2019; doi:10.7150/thno.38287; in press
[Author manuscript]

Loss of histone macroH2A1 in hepatocellular carcinoma cells promotes paracrine-mediated chemoresistance and CD4+CD25+FoxP3+ regulatory T cells activation
Oriana Lo Re, Tommaso Mazza, Sebastiano Giallongo, Paola Sanna, Francesca Rappa, Tu Vinh Luong, Giovanni Li Volti, Adela Drovakova, Tania Roskams, Matthias Van Haele, Emmanuel Tsochatzis, Manlio Vinciguerra
Theranostics 2019; doi:10.7150/thno.35045; in press
[Author manuscript]

Histone deacetylase inhibition is synthetically lethal with arginine deprivation in pancreatic cancers with low argininosuccinate synthetase 1 expression
Stephanie S. Kim, Shili Xu, Jing Cui, Soumya Poddar, Thuc M. Le, Hovhannes Hayrapetyan, Luyi Li, Nanping Wu, Alexandra M. Moore, Lei Zhou, Alice C. Yu, Amanda M. Dann, Irmina A. Elliott, Evan R. Abt, Woosuk Kim, David W. Dawson, Caius G. Radu, Timothy R. Donahue
Theranostics 2019; doi:10.7150/thno.40195; in press
[Author manuscript]

Gold nanoclusters elicit homeostatic perturbations in glioblastoma cells and adaptive changes of lysosomes
Dusica Maysinger, Evan R. Gran, Franck Bertorelle, Hussein Fakhouri, Rodolphe Antoine, Esha S. Kaul, Dana M. Samhadaneh, Ursula Stochaj
Theranostics 2019; doi:10.7150/thno.37674; accepted
[Author manuscript]

Ultrasmall CuS @BSA nanoparticles with mild photothermal conversion synergistically induce MSCs-differentiated fibroblast and improve skin regeneration
Yao Xiao, Jinrong Peng, Qingya Liu, Lijuan Chen, Zhiyong Qian
Theranostics 2019; doi:10.7150/thno.39471; in press
[Author manuscript]

Silica Perturbs Primary Cilia and Causes Myofibroblast Differentiation during Silicosis by Reduction of the KIF3A-Repressor GLI3 Complex
Shifeng Li, Zhongqiu Wei, Gengxu Li, Qiaodan Zhang, Siyu Niu, Dingjie Xu, Na Mao, Si Chen, Xuemin Gao, Wenchen Cai, Ying Zhu, Guizhen Zhang, Dan Li, Xue Yi, Fang Yang and Hong Xu
Theranostics 2019; doi:10.7150/thno.37049; in press
[Author manuscript]

Neutrophil infiltration and whole-cell vaccine elicited by N-dihydrogalactochitosan combined with NIR phototherapy to enhance antitumor immune response and T cell immune memory
Shuhong Qi, Lisen Lu, Feifan Zhou, Yuzhou Chen, Mengli Xu, Lu Chen, Xiang Yu, Wei R. Chen and Zhihong Zhang
Theranostics 2019; doi:10.7150/thno.38515; accepted
[Author manuscript]

Specific targeting of PDGFRβ in the stroma inhibits growth and angiogenesis in tumors with high PDGF-BB expression
Maria Tsioumpekou, Sara I. Cunha, Haisha Ma, Aive Åhgren, Jessica Cedervall, Anna-Karin Olsson, Carl-Henrik Heldin and Johan Lennartsson
Theranostics 2019; doi:10.7150/thno.37851; in press
[Author manuscript]

Current progress of extracellular vesicles in prostate cancer early diagnosis
Bairen Pang, Ying Zhu, Jie Ni, James Thompson, David Malouf, Joseph Bucci, Peter Graham, Yong Li
Theranostics 2019; doi:10.7150/thno.39486; accepted
[Author manuscript]

Acute cellular and vascular responses to photodynamic therapy using EGFR-targeted nanobody-photosensitizer conjugates studied with intravital optical imaging and magnetic resonance imaging
Henriette S. de Bruijn, Vida Mashayekhi, Tom J.L. Schreurs, Pieter B.A.A. van Driel, Gustav J. Strijkers, Paul J. van Diest, Clemens W.G.M. Lowik, Ann L.B. Seynhaeve, Timo L.M. ten Hagen, Jeanine J. Prompers, Paul M.P. van Bergen en Henegouwen, Dominic J. Robinson, Sabrina Oliveira
Theranostics 2019; doi:10.7150/thno.37949; accepted
[Author manuscript]

Potent antibacterial activity of MSI-1 derived from the magainin 2 peptide against drug-resistant bacteria
Lingman Ma, Xin Xie, Hanhan Liu, Ya Huang, Haomin Wu, Meiling Jiang, Pengfei Xu, Xinyue Ye, Changlin Zhou
Theranostics 2019; doi:10.7150/thno.39157; in press
[Author manuscript]

Red Blood Cell Membrane-Enveloped O2 self-supplementing biomimetic nanoparticles for tumor imaging-guided enhanced sonodynamic therapy
Cheng Li, Xiao-Quan Yang, Jie An, Kai Cheng, Xiao-Lin Hou, Xiao-Shuai Zhang, Yong-Guo Hu, Bo Liu, Yuan-Di Zhao
Theranostics 2019; doi:10.7150/thno.37930; in press
[Author manuscript]

Activation of JNK and p38 MAPK Mediated by ZDHHC17 Drives Glioblastoma Multiforme Development and Malignant Progression
Xueran Chen, Aijun Hao, Xian Li, Kaiqin Ye, Chenggang Zhao, Haoran Yang, Huihui Ma, Lei Hu, Zhiyang Zhao, Lizhu Hu, Fang Ye, Qiuyan Sun, Huaman Zhang, Hongzhi Wang, Xuebiao Yao and Zhiyou Fang
Theranostics 2019; doi:10.7150/thno.40076; in press
[Author manuscript]

Point-of-care cervical cancer screening using deep learning-based microholography
Divya Pathania, Christian Landeros, Lucas Rohrer, Victoria D’Agostino, Seonki Hong, Ismail Degani, Maria Avila-Wallace, Misha Pivovarov, Thomas Randall, Ralph Weissleder, Hakho Lee, Hyungsoon Im, and Cesar M. Castro
Theranostics 2019; doi:10.7150/thno.37187; accepted
[Author manuscript]

Formononetin attenuates atherosclerosis via regulating interaction between KLF4 and SRA in apoE-/- mice
Chuanrui Ma, Ronglin Xia, Shu Yang, Lipei Liu, Jing Zhang, Ke Feng, Yuna Shang, Jingtian Qu, Lingwei Li, Ning Chen, Shixin Xu, Wenwen Zhang, Jingyuan Mao, Jihong Han, Yuanli Chen, Xiaoxiao Yang, Yajun Duan, Guanwei Fan
Theranostics 2019; doi:10.7150/thno.38115; in press
[Author manuscript]

TGF-β inhibition combined with cytotoxic nanomedicine normalizes triple negative breast cancer microenvironment towards anti-tumor immunity
Myrofora Panagi, Chrysovalantis Voutouri, Fotios Mpekris, Panagiotis Papageorgis, Margaret R Martin, John D Martin, Philippos Demetriou, Chryso Pierides, Christiana Polydorou, Andreas Stylianou, Maria Louca, Laura Koumas, Paul Costeas, Kazunori Kataoka, Horacio Cabral, Triantafyllos Stylianopoulos
Theranostics 2019; doi:10.7150/thno.36936; accepted
[Author manuscript]

Two-dimensional nanomaterials beyond graphene for antibacterial applications: current progress and future perspectives
Linqiang Mei, Shuang Zhu, Wenyan Yin, Chunying Chen, Guangjun Nie, Zhanjun Gu and Yuliang Zhao
Theranostics 2019; doi:10.7150/thno.39701; in press
[Author manuscript]

In vivo photoacoustic imaging dynamically monitors the structural and functional changes of ischemic stroke at a very early stage
Jing Lv‡, Shi Li‡, Jinde Zhang, Fei Duan, Zhiyou Wu, Ronghe Chen, Maomao Chen, Shanshan Huang, Haosong Ma, and Liming Nie
Theranostics 2019; doi:10.7150/thno.38554; in press
[Author manuscript]

Upregulation of neuronal PGC-1α ameliorates cognitive impairment induced by chronic cerebral hypoperfusion
Bin Han, Wei Jiang, Haijie Liu, Junjie Wang, Xiaofeng Ma, Yan Feng, Chun Dang, Kai Zheng, Pan Cui, Yali Bu, Qing Mei Wang, Zhenyu Ju, Junwei Hao
Theranostics 2019; doi:10.7150/thno.37119; accepted
[Author manuscript]

Harnessing Monoclonal Antibodies for Molecular Imaging and Precision Theranostics
Niels Dammes and Dan Peer
Theranostics 2019; doi:10.7150/thno.37443; in press
[Author manuscript]

Therapeutic management of neuro-oncologic patients - potential relevance of CSF liquid biopsy
Louisa von Baumgarten, Jörg Kumbrink, Andreas Jung, Anna Reischer, Madeleine Flach, Sibylle Liebmann, Klaus H. Metzeler, Julian W. Holch, Maximilian Niyazi, Niklas Thon, Andreas Straube, Michael von Bergwelt-Baildon Volker Heinemann, Thomas Kirchner, C. Benedikt Westphalen
Theranostics 2019; doi:10.7150/thno.36884; in press
[Author manuscript]

Cancer immunotherapy is accompanied by distinct metabolic patterns in primary and secondary lymphoid organs observed by non-invasive in vivo 18F-FDG-PET
Johannes Schwenck, Barbara Schörg, Francesco Fiz, Dominik Sonanini, Andrea Forschner, Thomas Eigentler, Benjamin Weide, Manuela Martella, Irene Gonzalez-Menendez, Cristina Campi, Gianmario Sambuceti, Ferdinand Seith, Leticia Quintanilla-Martinez, Claus Garbe, Christina Pfannenberg, Martin Röcken, Christian la Fougere, Bernd J Pichler, Manfred Kneilling
Theranostics 2019; doi:10.7150/thno.35989; in press
[Author manuscript]

Molecular imaging biomarkers for immune checkpoint inhibitor therapy
Pim P van de Donk, Laura Kist de Ruijter, Marjolijn N Lub-de Hooge, Adrienne H Brouwers, Anthonie J van der Wekken, Sjoukje F Oosting, Rudolf SN Fehrmann, Derk Jan A de Groot, Elisabeth GE de Vries
Theranostics 2019; doi:10.7150/thno.38339; accepted
[Author manuscript]

The combination of bevacizumab/Avastin and erlotinib/Tarceva is relevant for the treatment of metastatic renal cell carcinoma: the role of a synonymous mutation of the EGFR receptor
Renaud Grépin, Mélanie Guyot, Aurore Dumond, Jérôme Durivault, Damien Ambrosetti, Jean-François Roussel, Florence Dupré, Hervé Quintens and Gilles Pagès
Theranostics 2019; doi:10.7150/thno.38346; accepted
[Author manuscript]

Aligned chitosan nanofiber hydrogel grafted with bioactive brain-derived neurotrophic factor and vascular endothelial growth factor mimicking peptides repair long-distance sciatic nerve defect in rats
Feng Rao, Yanhua Wang, Dianying Zhang, Changfeng Lu, Zheng Cao, Jiajie Sui, Mengjiao Wu, Yawen Zhang, Wei Pi, Bo Wang, Yuhui Kou, Xiumei Wang, Peixun Zhang, Baoguo Jiang
Theranostics 2019; doi:10.7150/thno.36272; accepted
[Author manuscript]

Imaging-assisted anticancer nanotherapy
Anshuman Dasgupta, Ilaria Biancacci, Fabian Kiessling, Twan Lammers
Theranostics 2019; doi:10.7150/thno.38288; in press
[Author manuscript]

Exosomes from nicotine-stimulated macrophages accelerate atherosclerosis through miR-21-3p/PTEN-mediated VSMC migration and proliferation
Jumo Zhu, Bei Liu, Zhiyan Wang, Di Wang, Huaner Ni, Lili Zhang and Yi Wang
Theranostics 2019; doi:10.7150/thno.37357; in press
[Author manuscript]

Understanding the EPR effect through image-guided systems pharmacology
Thomas S.C. Ng, Michelle A. Garlin, Ralph Weissleder, Miles A. Miller
Theranostics 2019; doi:10.7150/thno.37215; accepted
[Author manuscript]

Development of adamantane-conjugated TLR7/8 agonists for supramolecular delivery and cancer immunotherapy
Christopher B. Rodell, Maaz S. Ahmed, Christopher S. Garris, Mikael J. Pittet, Ralph Weissleder
Theranostics 2019; doi:10.7150/thno.35434; accepted
[Author manuscript]

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