ISSN: 1838-7640Theranostics
Global reach, higher impact
Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.
Research Paper
Intranasal delivery of engineered extracellular vesicles loaded with miR-206-3p antagomir ameliorates Alzheimer's disease phenotypes
Dong Peng, Tingting Liu, Huahui Lu, Lei Zhang, Hongxia Chen, Yadong Huang, Bo Hu, Qihao Zhang
Theranostics 2024; 14(19): 7623-7644. doi:10.7150/thno.103596
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Review
Virus-like particle encapsulation of functional proteins: advances and applications
Xianxun Sun, Yindong Lian, Tao Tian, Zongqiang Cui
Theranostics 2024; 14(19): 7604-7622. doi:10.7150/thno.103127
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Research Paper
A fluorogenic ROS-triggered hydrogen sulfide donor for alleviating cerebral ischemia-reperfusion injury
Huangjie Lu, Huiying Zeng, Wenlong Wei, Yuying Chen, Ziqiang Zhou, Xuyang Ning, Ping Hu
Theranostics 2024; 14(19): 7589-7603. doi:10.7150/thno.100930
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Research Paper
FBLN7 mediates vascular smooth muscle cell phenotype switching and vascular remodeling in hypertension
Guoqing Yao, Xuehui Zheng, Yang Hu, Yuan Zhao, Binghui Kong, Yun Ti, Pei li Bu
Theranostics 2024; 14(19): 7569-7588. doi:10.7150/thno.102593
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Research Paper
Rc3h1 negatively regulates osteoclastogenesis by limiting energy metabolism
Liuyuan Chen, Yuangang Su, Chaofeng Wang, Qian Huang, Weiwei Chen, Na Hai, Jikang Wang, Haoyu Lian, Jinmin Zhao, Jiake Xu, Qian Liu
Theranostics 2024; 14(19): 7554-7568. doi:10.7150/thno.99565
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Research Paper
An enzyme-mimicking reactive oxygen species scavenger targeting oxidative stress-inflammation cycle ameliorates IR-AKI by inhibiting pyruvate dehydrogenase kinase 4
Wenfang He, Chenguang Ding, Ting Lin, Binqi Wang, Wenjing Wang, Zhichao Deng, Taian Jin, Yiwei Shang, Danna Zheng, Ting Bai, Mingzhen Zhang, Runqing Li, Juan Jin, Qiang He
Theranostics 2024; 14(19): 7534-7553. doi:10.7150/thno.101229
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Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD
Editor-in-chief profile
Congratulations! Professor Chen has been elected as a member of the Academia Europaea.
- Theranostics is indexed by Science Citation Index (SCI) and MEDLINE. (Full index information)
- Full texts of articles in PubMed Central and Europe PMC. Abstracts in PubMed.
Rationale: Ischemia-reperfusion-induced acute kidney injury (IR-AKI), characterized by the abrupt decline in renal function, is distinguished by the intricate interplay between oxidative stress and inflammation. In this study, a reactive oxygen species (ROS) scavenger-CF@PDA was developed to effectively target antioxidant and anti-inflammatory pathways to disrupt the oxidative stress-inflammation cycle in IR-AKI. Methods: UV-vis absorption spectra, FTIR spectra, and TEM were employed to determine the successful construction of CF@P. ABTS, TMB, and NBT analyses were performed to detect the antioxidant....
Rationale: Osteoclasts are giant bone-resorbing cells that need vigorous mitochondrial respiration to support their activation. Rc3h1, an RNA-binding protein, precisely governs the homeostasis of mRNA. However, the precise role of Rc3h1 in regulating iron metabolism and mitochondrial respiration in osteoclasts is not yet understood. Methods: We generated Rc3h1-deficient mice in osteoclast precursors and mature osteoclasts. The bone mass and osteoclast activity in bone tissues were evaluated. Moreover, we assessed the differentiation, bone resorption, iron content, and mitochondrial function of....
Nanotheranostics is indexed in MEDLINE and PubMed Central ...
Research Paper
Development and assessment of a novel magnetic nanoparticle antibody-conjugate and aptamer-based assay (MNp-Ab-Ap assay) for the rapid diagnosis of pleural tuberculosis
Pratibha Sharma, Rakesh Kumar Gupta, Simran Aittan, Divya Anthwal, Manisha Dass, Rakesh Yadav, Ashish Behera, Abhijeet Dhiman, Sahajal Dhooria, Sunil Sethi, Ritu Singhal, Puneet Arora, Ashutosh Nath Aggarwal, Tarun Kumar Sharma, Sagarika Haldar
Nanotheranostics 2025; 9(1): 20-30.
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