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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.


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Research Paper
Visualization of a neurotropic flavivirus infection in mouse reveals unique viscerotropism controlled by host type I interferon signaling
Xiao-Feng Li, Xiao-Dan Li, Cheng-Lin Deng, Hao-Long Dong, Qiu-Yan Zhang, Qing Ye, Han-Qing Ye, Xing-Yao Huang, Yong-Qiang Deng, Bo Zhang, Cheng-Feng Qin
Theranostics 2017; 7(4): 912-925. doi:10.7150/thno.16615
[Abstract] [Full text] [PDF]


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Research Paper
Incorporating gold nanoclusters and target-directed liposomes as a synergistic amplified colorimetric sensor for HER2-positive breast cancer cell detection
Yu Tao, Mingqiang Li, Bumjun Kim, Debra T. Auguste
Theranostics 2017; 7(4): 899-911. doi:10.7150/thno.17927
[Abstract] [Full text] [PDF]


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Research Paper
Edaravone-Encapsulated Agonistic Micelles Rescue Ischemic Brain Tissue by Tuning Blood-Brain Barrier Permeability
Qu Jin, Yu Cai, Sihan Li, Haoran Liu, Xingyu Zhou, Chunqiang Lu, Xihui Gao, Jun Qian, Jun Zhang, Shenghong Ju, Cong Li
Theranostics 2017; 7(4): 884-898. doi:10.7150/thno.18219
[Abstract] [Full text] [PDF]


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Research Paper
Sensitive detection of protein biomarkers using silver nanoparticles enhanced immunofluorescence assay
Li-Jun Zhao, Ru-Jia Yu, Wei Ma, Huan-Xing Han, He Tian, Ruo-Can Qian, Yi-Tao Long
Theranostics 2017; 7(4): 876-883. doi:10.7150/thno.17575
[Abstract] [Full text] [PDF]


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Research Paper
A Crucial Role of CXCL14 for Promoting Regulatory T Cells Activation in Stroke
Hsu-Tung Lee, Shih-Ping Liu, Chen-Huan Lin, Sophie Wei Lee, Chung Y. Hsu, Huey-Kang Sytwu, Chia-Hung Hsieh, Woei-Cherng Shyu
Theranostics 2017; 7(4): 855-875. doi:10.7150/thno.17558
[Abstract] [Full text] [PDF]


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Research Paper
Phase-transitional Fe3O4/perfluorohexane Microspheres for Magnetic Droplet Vaporization
Ronghui Wang, Yang Zhou, Ping Zhang, Yu Chen, Wei Gao, Jinshun Xu, Hangrong Chen, Xiaojun Cai, Kun Zhang, Pan Li, Zhigang Wang, Bing Hu, Tao Ying, Yuanyi Zheng
Theranostics 2017; 7(4): 846-854. doi:10.7150/thno.17251
[Abstract] [Full text] [PDF]


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Review
Progress of small molecular inhibitors in the development of anti-influenza virus agents
Xiaoai Wu, Xiuli Wu, Qizheng Sun, Chunhui Zhang, Shengyong Yang, Lin Li, Zhiyun Jia
Theranostics 2017; 7(4): 826-845. doi:10.7150/thno.17071
[Abstract] [Full text] [PDF]


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Research Paper
Theranostic Nucleic Acid Binding Nanoprobe Exerts Anti-inflammatory and Cytoprotective Effects in Ischemic Injury
Howard H. Chen, Hushan Yuan, Hoonsung Cho, Yan Feng, Soeun Ngoy, Anand T. N. Kumar, Ronglih Liao, Wei Chao, Lee Josephson, David E. Sosnovik
Theranostics 2017; 7(4): 814-825. doi:10.7150/thno.17366
[Abstract] [Full text] [PDF]


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Research Paper
Preclinical Melanoma Imaging with 68Ga-Labeled α-Melanocyte-Stimulating Hormone Derivatives Using PET
Chengcheng Zhang, Zhengxing Zhang, Kuo-Shyan Lin, Jinhe Pan, Iulia Dude, Navjit Hundal-Jabal, Nadine Colpo, François Bénard
Theranostics 2017; 7(4): 805-813. doi:10.7150/thno.17117
[Abstract] [Full text] [PDF]


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Review
Progress in Exosome Isolation Techniques
Pin Li, Melisa Kaslan, Sze Han Lee, Justin Yao, Zhiqiang Gao
Theranostics 2017; 7(3): 789-804. doi:10.7150/thno.18133
[Abstract] [Full text] [PDF]


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Research Paper
Liposomal Nanoparticles Carrying anti-IL6R Antibody to the Tumour Microenvironment Inhibit Metastasis in Two Molecular Subtypes of Breast Cancer Mouse Models
Chunlei Guo, Yanan Chen, Wenjuan Gao, Antao Chang, Yujie Ye, Wenzhi Shen, Yunping Luo, Shengyong Yang, Peiqing Sun, Rong Xiang, Na Li
Theranostics 2017; 7(3): 775-788. doi:10.7150/thno.17237
[Abstract] [Full text] [PDF]


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Research Paper
Size-Tunable Gd2O3@Albumin Nanoparticles Conjugating Chlorin e6 for Magnetic Resonance Imaging-Guided Photo-Induced Therapy
Lijuan Zhou, Tao Yang, Junxing Wang, Qiaoli Wang, Xiaoyan Lv, Hengte Ke, Zhengqing Guo, Junkang Shen, Yong Wang, Chungen Xing, Huabing Chen
Theranostics 2017; 7(3): 764-774. doi:10.7150/thno.15757
[Abstract] [Full text] [PDF]


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Review
Leukocyte-mediated Delivery of Nanotherapeutics in Inflammatory and Tumor Sites
Xinyue Dong, Dafeng Chu, Zhenjia Wang
Theranostics 2017; 7(3): 751-763. doi:10.7150/thno.18069
[Abstract] [Full text] [PDF]


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Research Paper
Exosomes derived from human platelet-rich plasma prevent apoptosis induced by glucocorticoid-associated endoplasmic reticulum stress in rat osteonecrosis of the femoral head via the Akt/Bad/Bcl-2 signal pathway
Shi-Cong Tao, Ting Yuan, Bi-Yu Rui, Zhen-Zhong Zhu, Shang-Chun Guo, Chang-Qing Zhang
Theranostics 2017; 7(3): 733-750. doi:10.7150/thno.17450
[Abstract] [Full text] [PDF]


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Research Paper
HER Family Receptors are Important Theranostic Biomarkers for Cervical Cancer: Blocking Glucose Metabolism Enhances the Therapeutic Effect of HER Inhibitors
Olga Martinho, Renato Silva-Oliveira, Fernanda P. Cury, Ana Martins Barbosa, Sara Granja, Adriane Feijó Evangelista, Fábio Marques, Vera Miranda-Gonçalves, Diana Cardoso-Carneiro, Flávia E. de Paula, Maicon Zanon, Cristovam Scapulatempo-Neto, Marise A.R. Moreira, Fátima Baltazar, Adhemar Longatto-Filho, Rui Manuel Reis
Theranostics 2017; 7(3): 717-732. doi:10.7150/thno.17154
[Abstract] [Full text] [PDF]


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Research Paper
Intracellularly Swollen Polypeptide Nanogel Assists Hepatoma Chemotherapy
Bo Shi, Kexin Huang, Jianxun Ding, Weiguo Xu, Yu Yang, Haiyan Liu, Lesan Yan, Xuesi Chen
Theranostics 2017; 7(3): 703-716. doi:10.7150/thno.16794
[Abstract] [Full text] [PDF]

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD, Chief, Laboratory of Molecular Imaging and Nanomedicine, NIBIB, NIH*
* Dr. Chen is serving in his personal capacity.
Editor-in-chief profile
new Impact factor is 8.854, according to 2016 release of Journal Citation Reports®. Congratulations!

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Most Cited Paper Award for year 2016: Winners of this year are Lian Jin, Xin Zeng, Ming Liu, Yan Deng, Nongyue He, for the paper "Current Progress in Gene Delivery Technology Based on Chemical Methods and Nano-carriers". Details ...
Theme Issue on “Brain Theranostics. Guest Editor: Prof. Rachela Popovtzer, PhD
Theme Issue on “Stem Cell Theranostics. Guest Editors: Kristopher Kilian, PhD, and Deok-Ho Kim, PhD
Theme Issue on “Biomolecular and biomimetic materials for theranostics. Guest Editors: Haiyun Song, PhD, and Chunhai Fan, PhD
Theme Issue on “Translational theranostics for infectious diseases. Guest Editor: Dr. Tony Y. Hu, Houston Methodist Research Institute
Theme Issue on “Light-Mediated Deep-Tissue Theranostics. Guest Editors: Dr. Gang Han, University of Massachusetts Medical School, and Dr. Jin Xie, University of Georgia
new Congratulations to Dr. Chen for receiving the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.
NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Published Special Issues