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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.

Latest articles:


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Research Paper
Cancer Theranostic Nanoparticles Self-Assembled from Amphiphilic Small Molecules with Equilibrium Shift-Induced Renal Clearance
Yuan Ma, Quanbing Mou, Mo Sun, Chunyang Yu, Jianqi Li, Xiaohua Huang, Xinyuan Zhu, Deyue Yan, Jian Shen
Theranostics 2016; 6(10): 1703-1716. doi:10.7150/thno.15647
[Abstract] [Full text] [PDF]


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Review
Optical Aptasensors for Adenosine Triphosphate
Stella Ng, Hui Si Lim, Qian Ma, Zhiqiang Gao
Theranostics 2016; 6(10): 1683-1702. doi:10.7150/thno.15850
[Abstract] [Full text] [PDF]


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Research Paper
RGD Peptide Cell-Surface Display Enhances the Targeting and Therapeutic Efficacy of Attenuated Salmonella-mediated Cancer Therapy
Seung-Hwan Park, Jin Hai Zheng, Vu Hong Nguyen, Sheng-Nan Jiang, Dong-Yeon Kim, Michael Szardenings, Jung Hyun Min, Yeongjin Hong, Hyon E. Choy, Jung-Joon Min
Theranostics 2016; 6(10): 1672-1682. doi:10.7150/thno.16135
[Abstract] [Full text] [PDF]


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Review
Standards and Methodologies for Characterizing Radiobiological Impact of High-Z Nanoparticles
Anna Subiel, Reece Ashmore, Giuseppe Schettino
Theranostics 2016; 6(10): 1651-1671. doi:10.7150/thno.15019
[Abstract] [Full text] [PDF]


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Research Paper
Gastrin-releasing Peptide Receptor Imaging in Breast Cancer Using the Receptor Antagonist 68Ga-RM2 And PET
Christian Stoykow, Thalia Erbes, Helmut R Maecke, Stefan Bulla, Mark Bartholomä, Sebastian Mayer, Vanessa Drendel, Peter Bronsert, Martin Werner, Gerald Gitsch, Wolfgang A Weber, Elmar Stickeler, Philipp T Meyer
Theranostics 2016; 6(10): 1641-1650. doi:10.7150/thno.14958
[Abstract] [Full text] [PDF]


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Research Paper
High-Resolution PET Imaging with Therapeutic Antibody-based PD-1/PD-L1 Checkpoint Tracers
Michael Hettich, Friederike Braun, Mark D. Bartholomä, Reinhold Schirmbeck, Gabriele Niedermann
Theranostics 2016; 6(10): 1629-1640. doi:10.7150/thno.15253
[Abstract] [Full text] [PDF]


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Research Paper
68Ga-HBED-CC-PSMA PET/CT Versus Histopathology In Primary Localized Prostate Cancer: A Voxel-Wise Comparison
Constantinos Zamboglou, Florian Schiller, Tobias Fechter, Gesche Wieser, Cordula Annette Jilg, Alin Chirindel, Nasr Salman, Vanessa Drendel, Martin Werner, Michael Mix, Philipp Tobias Meyer, Anca Ligia Grosu
Theranostics 2016; 6(10): 1619-1628. doi:10.7150/thno.15344
[Abstract] [Full text] [PDF]


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Research Paper
Comparison between Three Promising ß-emitting Radionuclides, 67Cu, 47Sc and 161Tb, with Emphasis on Doses Delivered to Minimal Residual Disease
Christophe Champion, Michele A. Quinto, Clément Morgat, Paolo Zanotti-Fregonara, Elif Hindié
Theranostics 2016; 6(10): 1611-1618. doi:10.7150/thno.15132
[Abstract] [Full text] [PDF]


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Research Paper
Holographic Assessment of Lymphoma Tissue (HALT) for Global Oncology Field Applications
Divya Pathania, Hyungsoon Im, Aoife Kilcoyne, Aliyah R. Sohani, Lioubov Fexon, Misha Pivovarov, Jeremy S. Abramson, Thomas C. Randall, Bruce A. Chabner, Ralph Weissleder, Hakho Lee, Cesar M. Castro
Theranostics 2016; 6(10): 1603-1610. doi:10.7150/thno.15534
[Abstract] [Full text] [PDF]


Editorial
The Pursuit of Theranostics with CEST MRI
Mark Marty Pagel
Theranostics 2016; 6(10): 1601-1602. doi:10.7150/thno.16337
[Abstract] [Full text] [PDF]


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Research Paper
Label-free CEST MRI Detection of Citicoline-Liposome Drug Delivery in Ischemic Stroke
Huanling Liu, Anna Jablonska, Yuguo Li, Suyi Cao, Dexiang Liu, Hanwei Chen, Peter CM Van Zijl, Jeff W.M. Bulte, Miroslaw Janowski, Piotr Walczak, Guanshu Liu
Theranostics 2016; 6(10): 1588-1600. doi:10.7150/thno.15492
[Abstract] [Full text] [PDF]


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Research Paper
Ultrasound-Mediated Microbubble Destruction (UMMD) Facilitates the Delivery of CA19-9 Targeted and Paclitaxel Loaded mPEG-PLGA-PLL Nanoparticles in Pancreatic Cancer
Lingxi Xing, Qiusheng Shi, Kailiang Zheng, Ming Shen, Jing Ma, Fan Li, Yang Liu, Lizhou Lin, Wenzhi Tu, Yourong Duan, Lianfang Du
Theranostics 2016; 6(10): 1573-1587. doi:10.7150/thno.15164
[Abstract] [Full text] [PDF]


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Research Paper
Assessing Therapeutic Potential of Magnetic Mesoporous Nanoassemblies for Chemo-Resistant Tumors
Lina Pradhan, Bhushan Thakur, Rohit Srivastava, Pritha Ray, Dhirendra Bahadur
Theranostics 2016; 6(10): 1557-1572. doi:10.7150/thno.15231
[Abstract] [Full text] [PDF]


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Research Paper
Ultrasound/Magnetic Targeting with SPIO-DOX-Microbubble Complex for Image-Guided Drug Delivery in Brain Tumors
Ching-Hsiang Fan, Yu-Hang Cheng, Chien-Yu Ting, Yi-Ju Ho, Po-Hung Hsu, Hao-Li Liu, Chih-Kuang Yeh
Theranostics 2016; 6(10): 1542-1556. doi:10.7150/thno.15297
[Abstract] [Full text] [PDF]


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Research Paper
Pharmacokinetic Behaviors of Intravenously Administered siRNA in Glandular Tissues
Yuanyu Huang, Qiang Cheng, Jia-Li Ji, Shuquan Zheng, Lili Du, Lingwei Meng, Yidi Wu, Deyao Zhao, Xiaoxia Wang, Li Lai, Huiqing Cao, Kai Xiao, Shan Gao, Zicai Liang
Theranostics 2016; 6(10): 1528-1541. doi:10.7150/thno.15246
[Abstract] [Full text] [PDF]


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Research Paper
Cell-Specific Promoters Enable Lipid-Based Nanoparticles to Deliver Genes to Specific Cells of the Retina In Vivo
Yuhong Wang, Ammaji Rajala, Binrui Cao, Michelle Ranjo-Bishop, Martin-Paul Agbaga, Chuanbin Mao, Raju V.S. Rajala
Theranostics 2016; 6(10): 1514-1527. doi:10.7150/thno.15230
[Abstract] [Full text] [PDF]

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD, Chief, Laboratory of Molecular Imaging and Nanomedicine, NIBIB, NIH*
* Dr. Chen is serving in his personal capacity.
Editor-in-chief profile
new Impact factor is 8.854, according to 2016 release of Journal Citation Reports®. Congratulations!

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Most Cited Paper Award for year 2015: Winners of this year are Chao Wang, Liang Cheng, Zhuang Liu, for the paper "Upconversion Nanoparticles for Photodynamic Therapy and Other Cancer Therapeutics". Details ...
Theme Issue on “Light-Mediated Deep-Tissue Theranostics. Guest Editors: Dr. Gang Han, University of Massachusetts Medical School, and Dr. Jin Xie, University of Georgia
new Congratulations to Dr. Chen for receiving the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.
NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Published Special Issues