Cover image

Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.


toc.jpg

Research Paper
Versatile and Finely Tuned Albumin Nanoplatform based on Click Chemistry
Ji Yong Park, Myung Geun Song, Kyu Wan Kim, Nadeem Ahmed Lodhi, Jin Yeong Choi, Young Ju Kim, Jung Young Kim, Hyewon Chung, Chiwoo Oh, Yun-Sang Lee, Keon Wook Kang, Hyung-Jun Im, Seung Hyeok Seok, Dong Soo Lee, Edmund E. Kim, Jae Min Jeong
Theranostics 2019; 9(12): 3439-3450. doi:10.7150/thno.33143
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Knockdown of NEAT1 induces tolerogenic phenotype in dendritic cells by inhibiting activation of NLRP3 inflammasome
Maomao Zhang, Yang Zheng, Yong Sun, Shuang Li, Liangqi Chen, Xiangyuan Jin, Xinyu Hou, Xianglan Liu, Qi Chen, Jing Li, Mingyang Liu, Xianghui Zheng, Yongxiang Zhang, Jian Wu, Bo Yu
Theranostics 2019; 9(12): 3421-3438. doi:10.7150/thno.33178
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Carbon-gold hybrid nanoprobes for real-time imaging, photothermal/photodynamic and nanozyme oxidative therapy
Amin Zhang, Shaojun Pan, Yuhui Zhang, Jie Chang, Jin Cheng, Zhicheng Huang, Tianliang Li, Chunlei Zhang, Jesus Martinez de la Fuentea, Qian Zhang, Daxiang Cui
Theranostics 2019; 9(12): 3405-3420. doi:10.7150/thno.33266
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
RUNX2 overexpression and PTEN haploinsufficiency cooperate to promote CXCR7 expression and cellular trafficking, AKT hyperactivation and prostate tumorigenesis
Yang Bai, Yinhui Yang, Yuqian Yan, Jian Zhong, Alexandra M. Blee, Yunqian Pan, Tao Ma, R. Jeffrey Karnes, Rafael Jimenez, Wanhai Xu, Haojie Huang
Theranostics 2019; 9(12): 3388-3404. doi:10.7150/thno.33292
[Abstract] [Full text] [PDF]


toc.jpg

Review
Research tools for extrapolating the disposition and pharmacokinetics of nanomaterials from preclinical animals to humans
Michael S. Valic, Gang Zheng
Theranostics 2019; 9(11): 3365-3387. doi:10.7150/thno.34509
[Abstract] [Full text] [PDF]


toc.jpg

Review
Supramolecular Nanomachines as Stimuli-Responsive Gatekeepers on Mesoporous Silica Nanoparticles for Antibiotic and Cancer Drug Delivery
Chi-An Cheng, Tian Deng, Fang-Chu Lin, Yao Cai, Jeffrey I. Zink
Theranostics 2019; 9(11): 3341-3364. doi:10.7150/thno.34576
[Abstract] [Full text] [PDF]


toc.jpg

Review
Precise cell behaviors manipulation through light-responsive nano-regulators: recent advance and perspective
Thang Do Cong, Wang Zhimin, Lu Xiaoling, Xing Bengang
Theranostics 2019; 9(11): 3308-3340. doi:10.7150/thno.33888
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Ferroptosis promotes photodynamic therapy: supramolecular photosentizer-inducer nanodrug for enhanced cancer treatment
Ting Zhu, Leilei Shi, Chunyang Yu, Yabing Dong, Feng Qiu, Lingyue Shen, Qiuhui Qian, Guoyu Zhou, Xinyuan Zhu
Theranostics 2019; 9(11): 3293-3307. doi:10.7150/thno.32867
[Abstract] [Full text] [PDF]


toc.jpg

Review
Protein Delivery into the Cell Cytosol using Non-Viral Nanocarriers
Yi-Wei Lee, David C. Luther, Jessica A. Kretzmann, Andrew Burden, Taewon Jeon, Shumei Zhai, Vincent M. Rotello
Theranostics 2019; 9(11): 3280-3292. doi:10.7150/thno.34412
[Abstract] [Full text] [PDF]


toc.jpg

Review
DNA-supramolecule conjugates in theranostics
Kun Chen, Ting Fu, Weidi Sun, Qin Huang, Pengge Zhang, Zilong Zhao, Xiaobing Zhang, Weihong Tan
Theranostics 2019; 9(11): 3262-3279. doi:10.7150/thno.31885
[Abstract] [Full text] [PDF]


toc.jpg

Review
Peptide-modulated self-assembly as a versatile strategy for tumor supramolecular nanotheranostics
Shukun Li, Qianli Zou, Ruirui Xing, Thimmaiah Govindaraju, Rawil Fakhrullin, Xuehai Yan
Theranostics 2019; 9(11): 3249-3261. doi:10.7150/thno.31814
[Abstract] [Full text] [PDF]


toc.jpg

Review
AIE-based theranostic systems for detection and killing of pathogens
Xuewen He, Ling-Hong Xiong, Zheng Zhao, Zaiyu Wang, Liang Luo, Jacky Wing Yip Lam, Ryan Tsz Kin Kwok, Ben Zhong Tang
Theranostics 2019; 9(11): 3223-3248. doi:10.7150/thno.31844
[Abstract] [Full text] [PDF]


toc.jpg

Review
Supramolecular Assemblies of Peptides or Nucleopeptides for Gene Delivery
Huaimin Wang, Zhaoqianqi Feng, Bing Xu
Theranostics 2019; 9(11): 3213-3222. doi:10.7150/thno.31854
[Abstract] [Full text] [PDF]


toc.jpg

Review
Advances in intracellular delivery through supramolecular self-assembly of oligonucleotides and peptides
Jeonghwan Kim, Ashwanikumar Narayana, Siddharth Patel, Gaurav Sahay
Theranostics 2019; 9(11): 3191-3212. doi:10.7150/thno.33921
[Abstract] [Full text] [PDF]


toc.jpg

Review
Polyphenol-Based Particles for Theranostics
Qiong Dai, Huimin Geng, Qun Yu, Jingcheng Hao, Jiwei Cui
Theranostics 2019; 9(11): 3170-3190. doi:10.7150/thno.31847
[Abstract] [Full text] [PDF]


toc.jpg

Review
Recent Developments of Supramolecular Metal-based Structures for Applications in Cancer Therapy and Imaging
Alexander Pöthig, Angela Casini
Theranostics 2019; 9(11): 3150-3169. doi:10.7150/thno.31828
[Abstract] [Full text] [PDF]

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD
Editor-in-chief profile

newNanotheranostics is indexed in MEDLINE and PubMed Central. Submit manuscript now... Congratulations to Dr. Moritz F. Kircher who has been appointed Chair of the Department of Imaging and Radiology, Dana-Farber Cancer Institute, Harvard Medical School.

new CFP - Special Issue Targeting the Cancer Stem Cells. Guest Editor: Fei Chen, PhD, Professor, Wayne State University
new CFP - Special Issue Progress in Critical Reviews of Immunotheranostics. Guest Editors: Xiaoyuan (Shawn) Chen (NIBIB/NIH), Mingnan Chen (University of Utah)
new CFP - Special Issue Progress in Gene Editing Nanotheranostics. Guest Editors: Gang Han (University of Massachusetts Medical School), Wen Xue (University of Massachusetts Medical School), Qiaobing Xu (Tufts University)
Special Issue The EPR effect and beyond: Strategies to improve tumor targeting and nanomedicine efficacy. Guest Editors: Yang Shi (RWTH Aachen University), Roy van der Meel (Eindhoven University of Technology), Twan Lammers (RWTH Aachen University), Xiaoyuan (Shawn) Chen (NIBIB/NIH)
Special Issue Progress in Supramolecular Nanotheranostics. Guest Editors: Xiaoyuan (Shawn) Chen (NIBIB/NIH); Gang Zheng (University of Toronto); Jianjun Cheng (University of Illinois Urbana-Champaign); Yi-Yan Yang (Institute of Bioengineering and Nanotechnology, Singapore)

Congratulations to Dr. Chen for being elected as AIMBE fellow: http://aimbe.org/college-of-fellows/cof-2103/

Dr. Chen was recognized as Selected Highly Prolific Authors  (most published articles in the past 5 years) for 3 ACS journals (ACS Nano, Bioconjugate Chemistry, and Molecular Pharmaceutics). More details: http://journalstars.acs.org/

Dr. Chen received the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.

NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Published Special Issues