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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.

Latest articles:


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Research Paper
Intracellularly Swollen Polypeptide Nanogel Assists Hepatoma Chemotherapy
Bo Shi, Kexin Huang, Jianxun Ding, Weiguo Xu, Yu Yang, Haiyan Liu, Lesan Yan, Xuesi Chen
Theranostics 2017; 7(3): 703-716. doi:10.7150/thno.16794
[Abstract] [Full text] [PDF]


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Research Paper
Targeting and Regulating of an Oncogene via Nanovector Delivery of MicroRNA using Patient-Derived Tumor Xenografts
Shuyang Sun, Yilong Wang, Rong Zhou, Zicheng Deng, Yong Han, Xiao Han, Wenjie Tao, Zi Yang, Chaoji Shi, Duo Hong, Jiang Li, Donglu Shi, Zhiyuan Zhang
Theranostics 2017; 7(3): 677-693. doi:10.7150/thno.16357
[Abstract] [Full text] [PDF]


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Research Paper
STAT3/NF-κB-Regulated Lentiviral TK/GCV Suicide Gene Therapy for Cisplatin-Resistant Triple-Negative Breast Cancer
Wei-Ying Kuo, Luen Hwu, Chun-Yi Wu, Jhih-Shian Lee, Chi-Wei Chang, Ren-Shyan Liu
Theranostics 2017; 7(3): 647-663. doi:10.7150/thno.16827
[Abstract] [Full text] [PDF]


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Research Paper
MicroRNA Detection Using a Double Molecular Beacon Approach: Distinguishing Between miRNA and Pre-miRNA
Amanda Marie James, Meredith B. Baker, Gang Bao, Charles D. Searles
Theranostics 2017; 7(3): 634-646. doi:10.7150/thno.16840
[Abstract] [Full text] [PDF]


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Research Paper
Hybrid Imaging Labels: Providing the Link Between Mass Spectrometry-Based Molecular Pathology and Theranostics
Tessa Buckle, Steffen van der Wal, Stijn J.M. van Malderen, Larissa Müller, Joeri Kuil, Vincent van Unen, Ruud J.B. Peters, Margaretha E.M. van Bemmel, Liam A. McDonnell, Aldrik H. Velders, Frits Koning, Frank Vanhaeke, Fijs W. B. van Leeuwen
Theranostics 2017; 7(3): 624-633. doi:10.7150/thno.17484
[Abstract] [Full text] [PDF]


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Research Paper
Radionuclide I-131 Labeled Albumin-Paclitaxel Nanoparticles for Synergistic Combined Chemo-radioisotope Therapy of Cancer
Longlong Tian, Qian Chen, Xuan Yi, Guanglin Wang, Jie Chen, Ping Ning, Kai Yang, Zhuang Liu
Theranostics 2017; 7(3): 614-623. doi:10.7150/thno.17381
[Abstract] [Full text] [PDF]


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Research Paper
Anti-cancer Activity of Novel TM4SF5-Targeting Antibodies through TM4SF5 Neutralization and Immune Cell-Mediated Cytotoxicity
Hye-Mi Ahn, Jihye Ryu, Jin Myeong Song, Yunhee Lee, Hye-Jin Kim, Dongjoon Ko, Inpyo Choi, Sang Jick Kim, Jung Weon Lee, Semi Kim
Theranostics 2017; 7(3): 594-613. doi:10.7150/thno.15629
[Abstract] [Full text] [PDF]


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Research Paper
Direct Administration of Nerve-Specific Contrast to Improve Nerve Sparing Radical Prostatectomy
Connor W. Barth, Summer L. Gibbs
Theranostics 2017; 7(3): 573-593. doi:10.7150/thno.17433
[Abstract] [Full text] [PDF]


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Research Paper
Tracking Perfluorocarbon Nanoemulsion Delivery by 19F MRI for Precise High Intensity Focused Ultrasound Tumor Ablation
Soo Hyun Shin, Eun-Joo Park, Changki Min, Sun Il Choi, Soyeon Jeon, Yun-Hee Kim, Daehong Kim
Theranostics 2017; 7(3): 562-572. doi:10.7150/thno.16895
[Abstract] [Full text] [PDF]


Erratum
Retraction of “Tunable Plasmonic Nanoprobes for Theranostics of Prostate Cancer”
Ekaterina Y. Lukianova-Hleb, Alexander O. Oginsky, Adam P. Samaniego, Derek L. Shenefelt, Daniel S. Wagner, Jason H. Hafner, Mary C. Farach-Carson, Dmitri O. Lapotko
Theranostics 2017; 7(3): 561. doi:10.7150/thno.18746
[Abstract] [Full text] [PDF]


Erratum
Active Tumor Permeation and Uptake of Surface Charge-Switchable Theranostic Nanoparticles for Imaging-Guided Photothermal/Chemo Combinatorial Therapy: Erratum
Chia-Chian Hung, Wen-Chia Huang, Yi-Wen Lin, Ting-Wei Yu, Hsin-Hung Chen, Sung-Chyr Lin, Wen-Hsuan Chiang, Hsin-Cheng Chiu
Theranostics 2017; 7(3): 559-560. doi:10.7150/thno.18728
[Abstract] [Full text] [PDF]


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Review
Current Multistage Drug Delivery Systems Based on the Tumor Microenvironment
Binlong Chen, Wenbing Dai, Bing He, Hua Zhang, Xueqing Wang, Yiguang Wang, Qiang Zhang
Theranostics 2017; 7(3): 538-558. doi:10.7150/thno.16684
[Abstract] [Full text] [PDF]


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Research Paper
Enhanced Blood Suspensibility and Laser-Activated Tumor-specific Drug Release of Theranostic Mesoporous Silica Nanoparticles by Functionalizing with Erythrocyte Membranes
Jinghan Su, Huiping Sun, Qingshuo Meng, Pengcheng Zhang, Qi Yin, Yaping Li
Theranostics 2017; 7(3): 523-537. doi:10.7150/thno.17259
[Abstract] [Full text] [PDF]


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Research Paper
Precise Spatially Selective Photothermolysis Using Modulated Femtosecond Lasers and Real-time Multimodal Microscopy Monitoring
Yimei Huang, Harvey Lui, Jianhua Zhao, Zhenguo Wu, Haishan Zeng
Theranostics 2017; 7(3): 513-522. doi:10.7150/thno.17596
[Abstract] [Full text] [PDF]


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Research Paper
A specific dietary intervention to restore brain structure and function after ischemic stroke
Maximilian Wiesmann, Bastian Zinnhardt, Dirk Reinhardt, Sarah Eligehausen, Lydia Wachsmuth, Sven Hermann, Pieter J Dederen, Marloes Hellwich, Michael T Kuhlmann, Laus M Broersen, Arend Heerschap, Andreas H Jacobs, Amanda J Kiliaan
Theranostics 2017; 7(2): 493-512. doi:10.7150/thno.17559
[Abstract] [Full text] [PDF]


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Research Paper
Functional Genomic mRNA Profiling of Colorectal Adenomas: Identification and in vivo Validation of CD44 and Splice Variant CD44v6 as Molecular Imaging Targets
Elmire Hartmans, Veronique Orian-Rousseau, Alexandra Matzke-Ogi, Arend Karrenbeld, Derk Jan A. de Groot, Steven de Jong, Gooitzen M. van Dam, Rudolf S.N. Fehrmann, Wouter B. Nagengast
Theranostics 2017; 7(2): 482-492. doi:10.7150/thno.16816
[Abstract] [Full text] [PDF]

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD, Chief, Laboratory of Molecular Imaging and Nanomedicine, NIBIB, NIH*
* Dr. Chen is serving in his personal capacity.
Editor-in-chief profile
new Impact factor is 8.854, according to 2016 release of Journal Citation Reports®. Congratulations!

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Most Cited Paper Award for year 2016: Winners of this year are Lian Jin, Xin Zeng, Ming Liu, Yan Deng, Nongyue He, for the paper "Current Progress in Gene Delivery Technology Based on Chemical Methods and Nano-carriers". Details ...
Theme Issue on “Brain Theranostics. Guest Editor: Prof. Rachela Popovtzer, PhD
Theme Issue on “Stem Cell Theranostics. Guest Editors: Kristopher Kilian, PhD, and Deok-Ho Kim, PhD
Theme Issue on “Biomolecular and biomimetic materials for theranostics. Guest Editors: Haiyun Song, PhD, and Chunhai Fan, PhD
Theme Issue on “Translational theranostics for infectious diseases. Guest Editor: Dr. Tony Y. Hu, Houston Methodist Research Institute
Theme Issue on “Light-Mediated Deep-Tissue Theranostics. Guest Editors: Dr. Gang Han, University of Massachusetts Medical School, and Dr. Jin Xie, University of Georgia
new Congratulations to Dr. Chen for receiving the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.
NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Published Special Issues