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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.


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Research Paper
Dual-platform affinity proteomics identifies links between the recurrence of ovarian carcinoma and proteins released into the tumor microenvironment
Florian Finkernagel, Silke Reinartz, Maximiliane Schuldner, Alexandra Malz, Julia M. Jansen, Uwe Wagner, Thomas Worzfeld, Johannes Graumann, Elke Pogge von Strandmann, Rolf Müller
Theranostics 2019; 9(22): 6601-6617. doi:10.7150/thno.37549
[Abstract] [Full text] [PDF]


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Research Paper
Transplantation of human ESC-derived mesenchymal stem cell spheroids ameliorates spontaneous osteoarthritis in rhesus macaques
Bin Jiang, Xufeng Fu, Li Yan, Shanshan Li, Dongliang Zhao, Xiaoyan Wang, Yanchao Duan, Yaping Yan, Enqin Li, Kunhua Wu, Briauna Marie Inglis, Weizhi Ji, Ren-He Xu, Wei Si
Theranostics 2019; 9(22): 6587-6600. doi:10.7150/thno.35391
[Abstract] [Full text] [PDF]


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Research Paper
Targeted Delivery of Cisplatin-Derived Nanoprecursors via a Biomimetic Yeast Microcapsule for Tumor Therapy by the Oral Route
Xing Zhou, Kaijian Ling, Mengyu Liu, Xiangjun Zhang, Jun Ding, Yan Dong, Zhiqing Liang, Jianjun Li, Jianxiang Zhang
Theranostics 2019; 9(22): 6568-6586. doi:10.7150/thno.35353
[Abstract] [Full text] [PDF]


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Research Paper
Hypoxia-induced H19/YB-1 cascade modulates cardiac remodeling after infarction
Oi Kuan Choong, Chen-Yun Chen, Jianhua Zhang, Jen-Hao Lin, Po-Ju Lin, Shu-Chian Ruan, Timothy J. Kamp, Patrick C.H. Hsieh
Theranostics 2019; 9(22): 6550-6567. doi:10.7150/thno.35218
[Abstract] [Full text] [PDF]


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Research Paper
A stage-specific cancer chemotherapy strategy through flexible combination of reduction-activated charge-conversional core-shell nanoparticles
Lingfei Han, Yingming Wang, Xiaoxian Huang, Bowen Liu, Lejian Hu, Congyu Ma, Jun Liu, Jingwei Xue, Wei Qu, Fulei Liu, Feng Feng, Wenyuan Liu
Theranostics 2019; 9(22): 6532-6549. doi:10.7150/thno.35057
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Research Paper
VSTM2A suppresses colorectal cancer and antagonizes Wnt signaling receptor LRP6
Yujuan Dong, Yanquan Zhang, Wei Kang, Guoping Wang, Huarong Chen, Akira Higashimori, Geicho Nakatsu, Minnie Go, Joanna HM Tong, Shu Zheng, Ka Fai To, Joseph JY Sung, Xiaoyong Yang, Simon SM Ng, Jun Yu
Theranostics 2019; 9(22): 6517-6531. doi:10.7150/thno.34989
[Abstract] [Full text] [PDF]


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Research Paper
Cooperativity of co-factor NR2F2 with Pioneer Factors GATA3, FOXA1 in promoting ERα function
Guojuan Jiang, Xinrui Wang, Dandan Sheng, Lei Zhou, Yang Liu, Congling Xu, Suling Liu, Ji Zhang
Theranostics 2019; 9(22): 6501-6516. doi:10.7150/thno.34874
[Abstract] [Full text] [PDF]


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Research Paper
Effective chemoimmunotherapy by co-delivery of doxorubicin and immune adjuvants in biodegradable nanoparticles
Candido G. Da Silva, Marcel G.M. Camps, Tracy M.W.Y. Li, Luana Zerrillo, Clemens W. Löwik, Ferry Ossendorp, Luis J. Cruz
Theranostics 2019; 9(22): 6485-6500. doi:10.7150/thno.34429
[Abstract] [Full text] [PDF]


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Research Paper
BCAP31 drives TNBC development by modulating ligand-independent EGFR trafficking and spontaneous EGFR phosphorylation
Wenyan Fu, Hefen Sun, Yang Zhao, Mengting Chen, Xueli Yang, Yang Liu, Wei Jin
Theranostics 2019; 9(22): 6468-6484. doi:10.7150/thno.35383
[Abstract] [Full text] [PDF]


Erratum
Powerful anti-colon cancer effect of modified nanoparticle-mediated IL-15 immunogene therapy through activation of the host immune system: Erratum
Xiaoxiao Liu, Yanyan Li, Xiaodong Sun, Yagmur Muftuoglu, Bilan Wang, Ting Yu, Yuzhu Hu, Lu Ma, Mingli Xiang, Gang Guo, Chao You, Xiang Gao, Yuquan Wei
Theranostics 2019; 9(22): 6466-6467. doi:10.7150/thno.39082
[Abstract] [Full text] [PDF]


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Research Paper
Role of FOXC1 in regulating APSCs self-renewal via STI-1/PrPC signaling
Yi-Hui Lee, Hsu-Tung Lee, Chien-Lin Chen, Chi-Hao Chang, Chung Y. Hsu, Woei-Cherng Shyu
Theranostics 2019; 9(22): 6443-6465. doi:10.7150/thno.35619
[Abstract] [Full text] [PDF]


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Review
Targeted inhibition of STAT3 as a potential treatment strategy for atherosclerosis
Qi Chen, Jianjun Lv, Wenwen Yang, Baoping Xu, Zheng Wang, Zihao Yu, Jiawei Wu, Yang Yang, Yuehu Han
Theranostics 2019; 9(22): 6424-6442. doi:10.7150/thno.35528
[Abstract] [Full text] [PDF]


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Research Paper
Water-Soluble Phthalocyanines Selectively Bind to Albumin Dimers: A Green Approach Toward Enhancing Tumor-Targeted Photodynamic Therapy
Xingshu Li, Keunsoo Jeong, Yoonji Lee, Tian Guo, Dayoung Lee, Jeongmin Park, Nahyun Kwon, Jung-Hyun Na, Seung Kon Hong, Sun-Shin Cha, Jian-Dong Huang, Sun Choi, Sehoon Kim, Juyoung Yoon
Theranostics 2019; 9(22): 6412-6423. doi:10.7150/thno.35210
[Abstract] [Full text] [PDF]


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Research Paper
Macrophages facilitate post myocardial infarction arrhythmias: roles of gap junction and KCa3.1
Yu-Dong Fei, Qian Wang, Jian-Wen Hou, Wei Li, Xing-Xing Cai, Yu-Li Yang, Liu-Hui Zhang, Zhi-Xing Wei, Tai-Zhong Chen, Yue-Peng Wang, Yi-Gang Li
Theranostics 2019; 9(22): 6396-6411. doi:10.7150/thno.34801
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Research Paper
SDH5 Depletion Enhances Radiosensitivity by Regulating p53: A New Method for Noninvasive Prediction of Radiotherapy Response
Yan Zong, Qianwen Li, Furong Zhang, Xunde Xian, Sihua Wang, Jiahong Xia, Jie Li, Zhan Tuo, Guangqin Xiao, Li Liu, Guiling Li, Sheng Zhang, Gang Wu, Jun Liu
Theranostics 2019; 9(22): 6380-6395. doi:10.7150/thno.34443
[Abstract] [Full text] [PDF]


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Research Paper
Experimental pancreatic cancer develops in soft pancreas: novel leads for an individualized diagnosis by ultrafast elasticity imaging
Nicole Therville, Silvia Arcucci, Aurélie Vertut, Fernanda Ramos-Delgado, Dina Ferreira Da Mota, Marlène Dufresne, Céline Basset, Julie Guillermet-Guibert
Theranostics 2019; 9(22): 6369-6379. doi:10.7150/thno.34066
[Abstract] [Full text] [PDF]

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD
Editor-in-chief profile

newNanotheranostics is indexed in MEDLINE and PubMed Central. Submit manuscript now...

new CFP - Special Issue: Noble-metal Nanostructures for Theranostics. Guest Editors: Xiaohu Xia, University of Central Florida and Hui Wei, Nanjing University
Special Issue Targeting the Cancer Stem Cells. Guest Editor: Fei Chen, PhD, Professor, Wayne State University
Special Issue Progress in Critical Reviews of Immunotheranostics. Guest Editors: Xiaoyuan (Shawn) Chen (NIBIB/NIH), Mingnan Chen (University of Utah)
Special Issue Progress in Gene Editing Nanotheranostics. Guest Editors: Gang Han (University of Massachusetts Medical School), Wen Xue (University of Massachusetts Medical School), Qiaobing Xu (Tufts University)
Special Issue The EPR effect and beyond: Strategies to improve tumor targeting and nanomedicine efficacy. Guest Editors: Yang Shi (RWTH Aachen University), Roy van der Meel (Eindhoven University of Technology), Twan Lammers (RWTH Aachen University), Xiaoyuan (Shawn) Chen (NIBIB/NIH)
Special Issue Progress in Supramolecular Nanotheranostics. Guest Editors: Xiaoyuan (Shawn) Chen (NIBIB/NIH); Gang Zheng (University of Toronto); Jianjun Cheng (University of Illinois Urbana-Champaign); Yi-Yan Yang (Institute of Bioengineering and Nanotechnology, Singapore)

Congratulations to Dr. Chen for being elected as AIMBE fellow: http://aimbe.org/college-of-fellows/cof-2103/

Dr. Chen was recognized as Selected Highly Prolific Authors  (most published articles in the past 5 years) for 3 ACS journals (ACS Nano, Bioconjugate Chemistry, and Molecular Pharmaceutics). More details: http://journalstars.acs.org/

Dr. Chen received the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.

NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Published Special Issues