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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.

Latest articles:


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Research Paper
Blinking Phase-Change Nanocapsules Enable Background-Free Ultrasound Imaging
Alexander S. Hannah, Geoffrey P. Luke, Stanislav Y. Emelianov
Theranostics 2016; 6(11): 1866-1876. doi:10.7150/thno.14961
[Abstract] [Full text] [PDF]


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Research Paper
In vivo Biocompatibility, Biodistribution and Therapeutic Efficiency of Titania Coated Upconversion Nanoparticles for Photodynamic Therapy of Solid Oral Cancers
Sasidharan Swarnalatha Lucky, Niagara Muhammad Idris, Kai Huang, Jaejung Kim, Zhengquan Li, Patricia Soo Ping Thong, Rong Xu, Khee Chee Soo, Yong Zhang
Theranostics 2016; 6(11): 1844-1865. doi:10.7150/thno.15088
[Abstract] [Full text] [PDF]


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Research Paper
Polydopamine Coated Single-Walled Carbon Nanotubes as a Versatile Platform with Radionuclide Labeling for Multimodal Tumor Imaging and Therapy
He Zhao, Yu Chao, Jingjing Liu, Jie Huang, Jian Pan, Wanliang Guo, Jizhi Wu, Mao Sheng, Kai Yang, Jian Wang, Zhuang Liu
Theranostics 2016; 6(11): 1833-1843. doi:10.7150/thno.16047
[Abstract] [Full text] [PDF]


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Research Paper
Potentiation of Peptide Receptor Radionuclide Therapy by the PARP Inhibitor Olaparib
Julie Nonnekens, Melissa van Kranenburg, Cecile E.M.T. Beerens, Mustafa Suker, Michael Doukas, Casper H.J. van Eijck, Marion de Jong, Dik C. van Gent
Theranostics 2016; 6(11): 1821-1832. doi:10.7150/thno.15311
[Abstract] [Full text] [PDF]


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Research Paper
Silica Nanoparticles Target a Wnt Signal Transducer for Degradation and Impair Embryonic Development in Zebrafish
Hongyang Yi, Zhuyao Wang, Xiaojiao Li, Min Yin, Lihua Wang, Ali Aldalbahi, Nahed Nasser El-Sayed, Hui Wang, Nan Chen, Chunhai Fan, Haiyun Song
Theranostics 2016; 6(11): 1810-1820. doi:10.7150/thno.16127
[Abstract] [Full text] [PDF]


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Research Paper
Peripheral Blood Cell Gene Expression Diagnostic for Identifying Symptomatic Transthyretin Amyloidosis Patients: Male and Female Specific Signatures
Sunil M. Kurian, Marta Novais, Thomas Whisenant, Terri Gelbart, Joel N. Buxbaum, Jeffery W. Kelly, Teresa Coelho, Daniel R. Salomon
Theranostics 2016; 6(11): 1792-1809. doi:10.7150/thno.14584
[Abstract] [Full text] [PDF]


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Research Paper
Active-target T1-weighted MR Imaging of Tiny Hepatic Tumor via RGD Modified Ultra-small Fe3O4 Nanoprobes
Zhengyang Jia, Lina Song, Fengchao Zang, Jiacheng Song, Wei Zhang, Changzhi Yan, Jun Xie, Zhanlong Ma, Ming Ma, Gaojun Teng, Ning Gu, Yu Zhang
Theranostics 2016; 6(11): 1780-1791. doi:10.7150/thno.14280
[Abstract] [Full text] [PDF]


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Research Paper
Targeting Amino Acid Metabolism for Molecular Imaging of Inflammation Early After Myocardial Infarction
James T. Thackeray, Jens P. Bankstahl, Yong Wang, Kai C. Wollert, Frank M. Bengel
Theranostics 2016; 6(11): 1768-1779. doi:10.7150/thno.15929
[Abstract] [Full text] [PDF]


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Research Paper
PET Imaging with [18F]FSPG Evidences the Role of System xc- on Brain Inflammation Following Cerebral Ischemia in Rats
Maria Domercq, Boguslaw Szczupak, Jon Gejo, Vanessa Gómez-Vallejo, Daniel Padro, Kiran Babu Gona, Frédéric Dollé, Makoto Higuchi, Carlos Matute, Jordi Llop, Abraham Martín
Theranostics 2016; 6(11): 1753-1767. doi:10.7150/thno.15616
[Abstract] [Full text] [PDF]


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Research Paper
Ultrasound Molecular Imaging of the Breast Cancer Neovasculature using Engineered Fibronectin Scaffold Ligands: A Novel Class of Targeted Contrast Ultrasound Agent
Lotfi Abou-Elkacem, Katheryne E. Wilson, Sadie M. Johnson, Sayan M. Chowdhury, Sunitha Bachawal, Benjamin J. Hackel, Lu Tian, Jürgen K. Willmann
Theranostics 2016; 6(11): 1740-1752. doi:10.7150/thno.15169
[Abstract] [Full text] [PDF]


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Research Paper
Metal-linked Immunosorbent Assay (MeLISA): the Enzyme-Free Alternative to ELISA for Biomarker Detection in Serum
Ru-Jia Yu, Wei Ma, Xiao-Yuan Liu, Hong-Ying Jin, Huan-Xing Han, Hong-Yang Wang, He Tian, Yi-Tao Long
Theranostics 2016; 6(10): 1732-1739. doi:10.7150/thno.16129
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
Investigation of Particle Accumulation, Chemosensitivity and Thermosensitivity for Effective Solid Tumor Therapy Using Thermosensitive Liposomes and Hyperthermia
Wouter J.M. Lokerse, Michiel Bolkestein, Timo L.M. ten Hagen, Marion de Jong, Alexander M.M. Eggermont, Holger Grüll, Gerben A. Koning
Theranostics 2016; 6(10): 1717-1731. doi:10.7150/thno.14960
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
Cancer Theranostic Nanoparticles Self-Assembled from Amphiphilic Small Molecules with Equilibrium Shift-Induced Renal Clearance
Yuan Ma, Quanbing Mou, Mo Sun, Chunyang Yu, Jianqi Li, Xiaohua Huang, Xinyuan Zhu, Deyue Yan, Jian Shen
Theranostics 2016; 6(10): 1703-1716. doi:10.7150/thno.15647
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Review
Optical Aptasensors for Adenosine Triphosphate
Stella Ng, Hui Si Lim, Qian Ma, Zhiqiang Gao
Theranostics 2016; 6(10): 1683-1702. doi:10.7150/thno.15850
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
RGD Peptide Cell-Surface Display Enhances the Targeting and Therapeutic Efficacy of Attenuated Salmonella-mediated Cancer Therapy
Seung-Hwan Park, Jin Hai Zheng, Vu Hong Nguyen, Sheng-Nan Jiang, Dong-Yeon Kim, Michael Szardenings, Jung Hyun Min, Yeongjin Hong, Hyon E. Choy, Jung-Joon Min
Theranostics 2016; 6(10): 1672-1682. doi:10.7150/thno.16135
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Review
Standards and Methodologies for Characterizing Radiobiological Impact of High-Z Nanoparticles
Anna Subiel, Reece Ashmore, Giuseppe Schettino
Theranostics 2016; 6(10): 1651-1671. doi:10.7150/thno.15019
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD, Chief, Laboratory of Molecular Imaging and Nanomedicine, NIBIB, NIH*
* Dr. Chen is serving in his personal capacity.
Editor-in-chief profile
new Impact factor is 8.854, according to 2016 release of Journal Citation Reports®. Congratulations!

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Most Cited Paper Award for year 2015: Winners of this year are Chao Wang, Liang Cheng, Zhuang Liu, for the paper "Upconversion Nanoparticles for Photodynamic Therapy and Other Cancer Therapeutics". Details ...
Theme Issue on “Light-Mediated Deep-Tissue Theranostics. Guest Editors: Dr. Gang Han, University of Massachusetts Medical School, and Dr. Jin Xie, University of Georgia
new Congratulations to Dr. Chen for receiving the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.
NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Published Special Issues