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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.


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Commentary
Does H2 Alter Mitochondrial Bioenergetics via GHS-R1α Activation?
Sergej M. Ostojic
Theranostics 2017; 7(5): 1330-1332. doi:10.7150/thno.18745
[Abstract] [Full text] [PDF]


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Review
Ultrasound Elastography: Review of Techniques and Clinical Applications
Rosa M.S. Sigrist, Joy Liau, Ahmed El Kaffas, Maria Cristina Chammas, Juergen K. Willmann
Theranostics 2017; 7(5): 1303-1329. doi:10.7150/thno.18650
[Abstract] [Full text] [PDF]


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Research Paper
Design of Tumor Acidity-Responsive Sheddable Nanoparticles for Fluorescence/Magnetic Resonance Imaging-Guided Photodynamic Therapy
Feng Fan, Yue Yu, Fei Zhong, Meng Gao, Tianmeng Sun, Jiaxin Liu, Huimao Zhang, Haisheng Qian, Wei Tao, Xianzhu Yang
Theranostics 2017; 7(5): 1290-1302. doi:10.7150/thno.18557
[Abstract] [Full text] [PDF]


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Research Paper
Hypertension, cerebrovascular impairment, and cognitive decline in aged AβPP/PS1 mice
Maximilian Wiesmann, Valerio Zerbi, Diane Jansen, Dieter Lütjohann, Andor Veltien, Arend Heerschap, Amanda J Kiliaan
Theranostics 2017; 7(5): 1277-1289. doi:10.7150/thno.18509
[Abstract] [Full text] [PDF]


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Research Paper
Clinical efficacy of omalizumab in chronic spontaneous urticaria is associated with a reduction of FcεRI-positive cells in the skin
Martin Metz, Petra Staubach, Andrea Bauer, Randolf Brehler, Janine Gericke, Michael Kangas, Joanna Ashton-Chess, Philip Jarvis, Panayiotis Georgiou, Janice Canvin, Rainer Hillenbrand, Veit J. Erpenbeck, Marcus Maurer
Theranostics 2017; 7(5): 1266-1276. doi:10.7150/thno.18304
[Abstract] [Full text] [PDF]


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Research Paper
Design and Development of Fluorescent Vemurafenib Analogs for In Vivo Imaging
Hannes Mikula, Shawn Stapleton, Rainer H. Kohler, Claudio Vinegoni, Ralph Weissleder
Theranostics 2017; 7(5): 1257-1265. doi:10.7150/thno.18238
[Abstract] [Full text] [PDF]


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Research Paper
A Programmed Nanoparticle with Self-Adapting for Accurate Cancer Cell Eradication and Therapeutic Self-Reporting
Yingping Luo, Liwei Huang, Ye Yang, Xianfei Zhuang, Siyao Hu, Huangxian Ju, Bo-Yang Yu, Jiangwei Tian
Theranostics 2017; 7(5): 1245-1256. doi:10.7150/thno.18187
[Abstract] [Full text] [PDF]


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Research Paper
Recipient Glycemic Micro-environments Govern Therapeutic Effects of Mesenchymal Stem Cell Infusion on Osteopenia
Bing-Dong Sui, Cheng-Hu Hu, Chen-Xi Zheng, Yi Shuai, Xiao-Ning He, Ping-Ping Gao, Pan Zhao, Meng Li, Xin-Yi Zhang, Tao He, Kun Xuan, Yan Jin
Theranostics 2017; 7(5): 1225-1244. doi:10.7150/thno.18181
[Abstract] [Full text] [PDF]


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Research Paper
Size-dependent Effects of Gold Nanoparticles on Osteogenic Differentiation of Human Periodontal Ligament Progenitor Cells
Yangheng Zhang, Na Kong, Yuanchao Zhang, Wenrong Yang, Fuhua Yan
Theranostics 2017; 7(5): 1214-1224. doi:10.7150/thno.17252
[Abstract] [Full text] [PDF]


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Research Paper
Aptamer Internalization via Endocytosis Inducing S-Phase Arrest and Priming Maver-1 Lymphoma Cells for Cytarabine Chemotherapy
Huan Li, Shuanghui Yang, Ge Yu, Liangfang Shen, Jia Fan, Ling Xu, Hedong Zhang, Nianxi Zhao, Zihua Zeng, Tony Hu, Jianguo Wen, Youli Zu
Theranostics 2017; 7(5): 1204-1213. doi:10.7150/thno.17069
[Abstract] [Full text] [PDF]


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Research Paper
Phosphorylcholine-based stealthy nanocapsules enabling tumor microenvironment-responsive doxorubicin release for tumor suppression
Gan Liu, Hsiang-i Tsai, Xiaowei Zeng, Yixiong Zuo, Wei Tao, Jun Han, Lin Mei
Theranostics 2017; 7(5): 1192-1203. doi:10.7150/thno.17881
[Abstract] [Full text] [PDF]


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Research Paper
Tumor Hypoxia Regulates Forkhead Box C1 to Promote Lung Cancer Progression
Yu-Jung Lin, Woei-Cherng Shyu, Chi-Wei Chang, Chi-Chung Wang, Chung-Pu Wu, Hsu-Tung Lee, Liang-Jwu Chen, Chia-Hung Hsieh
Theranostics 2017; 7(5): 1177-1191. doi:10.7150/thno.17895
[Abstract] [Full text] [PDF]


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Research Paper
Physiological Effects of Ac4ManNAz and Optimization of Metabolic Labeling for Cell Tracking
Sang-Soo Han, Dong-Eun Lee, Hye-Eun Shim, Sangmin Lee, Taekhee Jung, Jung-Hwa Oh, Hyang-Ae Lee, Sung-Hwan Moon, Jongho Jeon, Seokjoo Yoon, Kwangmeyung Kim, Sun-Woong Kang
Theranostics 2017; 7(5): 1164-1176. doi:10.7150/thno.17711
[Abstract] [Full text] [PDF]


Editorial
The NETPET Score: Combining FDG and Somatostatin Receptor Imaging for Optimal Management of Patients with Metastatic Well-Differentiated Neuroendocrine Tumors
Elif Hindié
Theranostics 2017; 7(5): 1159-1163. doi:10.7150/thno.19588
[Abstract] [Full text] [PDF]


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Research Paper
Dual Somatostatin Receptor/FDG PET/CT Imaging in Metastatic Neuroendocrine Tumours: Proposal for a Novel Grading Scheme with Prognostic Significance
David LH Chan, Nick Pavlakis, Geoffrey P Schembri, Elizabeth J Bernard, Edward Hsiao, Aimee Hayes, Tristan Barnes, Connie Diakos, Mustafa Khasraw, Jaswinder Samra, Enid Eslick, Paul J Roach, Alexander Engel, Stephen J Clarke, Dale L Bailey
Theranostics 2017; 7(5): 1149-1158. doi:10.7150/thno.18068
[Abstract] [Full text] [PDF]


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Research Paper
SiRNA Delivery with PEGylated Graphene Oxide Nanosheets for Combined Photothermal and Genetherapy for Pancreatic Cancer
Feng Yin, Kuan Hu, Yangzi Chen, Mengying Yu, Dongyuan Wang, Qianqian Wang, Ken-Tye Yong, Fei Lu, Yongye Liang, Zigang Li
Theranostics 2017; 7(5): 1133-1148. doi:10.7150/thno.17841
[Abstract] [Full text] [PDF]

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD, Chief, Laboratory of Molecular Imaging and Nanomedicine, NIBIB, NIH*
* Dr. Chen is serving in his personal capacity.
Editor-in-chief profile
new Impact factor is 8.854, according to 2016 release of Journal Citation Reports®. Congratulations!

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Most Cited Paper Award for year 2016: Winners of this year are Lian Jin, Xin Zeng, Ming Liu, Yan Deng, Nongyue He, for the paper "Current Progress in Gene Delivery Technology Based on Chemical Methods and Nano-carriers". Details ...
Theme Issue on “Brain Theranostics. Guest Editor: Prof. Rachela Popovtzer, PhD
Theme Issue on “Stem Cell Theranostics. Guest Editors: Kristopher Kilian, PhD, and Deok-Ho Kim, PhD
Theme Issue on “Biomolecular and biomimetic materials for theranostics. Guest Editors: Haiyun Song, PhD, and Chunhai Fan, PhD
Theme Issue on “Translational theranostics for infectious diseases. Guest Editor: Dr. Tony Y. Hu, Houston Methodist Research Institute
Theme Issue on “Light-Mediated Deep-Tissue Theranostics. Guest Editors: Dr. Gang Han, University of Massachusetts Medical School, and Dr. Jin Xie, University of Georgia
new Congratulations to Dr. Chen for receiving the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.
NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Published Special Issues