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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.

Latest articles:


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Review
Functional Nanostructures for Effective Delivery of Small Interfering RNA Therapeutics
Cheol Am Hong, Yoon Sung Nam
Theranostics 2014; 4(12): 1211-1232. doi:10.7150/thno.8491
[Abstract] [Full text] [PDF]


Editorial
Multidisciplinary Efforts Driving Translational Theranostics
Tony Y. Hu
Theranostics 2014; 4(12): 1209-1210. doi:10.7150/thno.10503
[Abstract] [Full text] [PDF]


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Research Paper
MiR-194 Deregulation Contributes To Colorectal Carcinogenesis via Targeting AKT2 Pathway
Hui-Jun Zhao, Lin-Lin Ren, Zhen-Hua Wang, Tian-Tian Sun, Ya-Nan Yu, Ying-Chao Wang, Ting-Ting Yan, Weiping Zou, Jie He, Yaou Zhang, Jie Hong, Jing-Yuan Fang
Theranostics 2014; 4(12): 1193-1208. doi:10.7150/thno.8712
[Abstract] [Full text] [PDF]


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Review
MicroRNAs Associated With HBV Infection And HBV-related HCC
Kun-Lin Xie, Yan-Ge Zhang, Jun Liu, Yong Zeng, Hong Wu
Theranostics 2014; 4(12): 1176-1192. doi:10.7150/thno.8715
[Abstract] [Full text] [PDF]


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Research Paper
Quantitative Proteomics Analysis Identifies Mitochondria as Therapeutic Targets of Multidrug-Resistance in Ovarian Cancer
Xiulan Chen, Shasha Wei, Ying Ma, Jie Lu, Gang Niu, Yanhong Xue, Xiaoyuan Chen, Fuquan Yang
Theranostics 2014; 4(12): 1164-1175. doi:10.7150/thno.8502
[Abstract] [Full text] [PDF]


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Research Paper
Glycoproteomic Study Reveals Altered Plasma Proteins Associated with HIV Elite Suppressors
Weiming Yang, Oliver Laeyendecker, Sarah K. Wendel, Bai Zhang, Shisheng Sun, Jian-Ying Zhou, Minghui Ao, Richard D. Moore, J. Brooks Jackson, Hui Zhang
Theranostics 2014; 4(12): 1153-1163. doi:10.7150/thno.9510
[Abstract] [Full text] [PDF]


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Research Paper
Radiofrequency Heat-Enhanced Chemotherapy for Breast Cancer: Towards Interventional Molecular Image-Guided Chemotherapy
Yurong Zhou, Guocan Han, Yue Wang, Xi Hu, Zhiming Li, Lumin Chen, Weixian Bai, Jingfeng Luo, Yajing Zhang, Jihong Sun, Xiaoming Yang
Theranostics 2014; 4(11): 1145-1152. doi:10.7150/thno.10006
[Abstract] [Full text] [PDF]


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Short Research Communication
Ultrasound-Mediated Gene and Drug Delivery Using a Microbubble-Liposome Particle System
Young Il Yoon, Yong-Su Kwon, Hee-Sang Cho, Sun-Hee Heo, Kyeong Soon Park, Sang Gyu Park, Soo-Hong Lee, Seung Il Hwang, Young Il Kim, Hwan Jun Jae, Gook-Jun Ahn, Young-Seok Cho, Hakho Lee, Hak Jong Lee, Tae-Jong Yoon
Theranostics 2014; 4(11): 1133-1144. doi:10.7150/thno.9945
[Abstract] [Full text] [PDF]


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Research Paper
High-Purity Isolation and Recovery of Circulating Tumor Cells using Conducting Polymer-deposited Microfluidic Device
SeungHyun Jeon, WooYoung Hong, Eun Sook Lee, Youngnam Cho
Theranostics 2014; 4(11): 1123-1132. doi:10.7150/thno.9627
[Abstract] [Full text] [PDF]


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Research Paper
Photostimulable Near-Infrared Persistent Luminescent Nanoprobes for Ultrasensitive and Longitudinal Deep-Tissue Bio-Imaging
Yen-Jun Chuang, Zipeng Zhen, Fan Zhang, Feng Liu, Jyoti P. Mishra, Wei Tang, Hongmin Chen, Xinglu Huang, Lianchun Wang, Xiaoyuan Chen, Jin Xie, Zhengwei Pan
Theranostics 2014; 4(11): 1112-1122. doi:10.7150/thno.9710
[Abstract] [Full text] [PDF]


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Research Paper
Co-delivery of Doxorubicin and Bmi1 siRNA by Folate Receptor Targeted Liposomes Exhibits Enhanced Anti-Tumor Effects in vitro and in vivo
Tan Yang, Bin Li, ShiBo Qi, Yong Liu, Yongkang Gai, Peng Ye, Guang Yang, Wendian Zhang, Peng Zhang, Xingxing He, Weijie Li, Zhiping Zhang, Guangya Xiang, Chuanrui Xu
Theranostics 2014; 4(11): 1096-1111. doi:10.7150/thno.9423
[Abstract] [Full text] [PDF]


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Research Paper
Enhancing Therapeutic Effects of Docetaxel-Loaded Dendritic Copolymer Nanoparticles by Co-Treatment with Autophagy Inhibitor on Breast Cancer
Xudong Zhang, Ying Yang, Xin Liang, Xiaowei Zeng, Zhigang Liu, Wei Tao, Xiaojun Xiao, Hongbo Chen, Laiqiang Huang, Lin Mei
Theranostics 2014; 4(11): 1085-1095. doi:10.7150/thno.9933
[Abstract] [Full text] [PDF]


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Review
Intraoperative Imaging-Guided Cancer Surgery: From Current Fluorescence Molecular Imaging Methods to Future Multi-Modality Imaging Technology
Chongwei Chi, Yang Du, Jinzuo Ye, Deqiang Kou, Jingdan Qiu, Jiandong Wang, Jie Tian, Xiaoyuan Chen
Theranostics 2014; 4(11): 1072-1084. doi:10.7150/thno.9899
[Abstract] [Full text] [PDF]


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Research Paper
Multiparametric Spectroscopic Photoacoustic Imaging of Breast Cancer Development in a Transgenic Mouse Model
Katheryne E. Wilson, Sunitha V. Bachawal, Lu Tian, Jürgen K. Willmann
Theranostics 2014; 4(11): 1062-1071. doi:10.7150/thno.9922
[Abstract] [Full text] [PDF]


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Research Paper
Microtubule-Associated Protein Mdp3 Promotes Breast Cancer Growth and Metastasis
Tala, Songbo Xie, Xiaodong Sun, Xiaoou Sun, Jie Ran, Linlin Zhang, Dengwen Li, Min Liu, Gang Bao, Jun Zhou
Theranostics 2014; 4(10): 1052-1061. doi:10.7150/thno.9727
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
Megalin-Mediated Specific Uptake of Chitosan/siRNA Nanoparticles in Mouse Kidney Proximal Tubule Epithelial Cells Enables AQP1 Gene Silencing
Shan Gao, San Hein, Frederik Dagnæs-Hansen, Kathrin Weyer, Chuanxu Yang, Rikke Nielsen, Erik I Christensen, Robert A Fenton, Jørgen Kjems
Theranostics 2014; 4(10): 1039-1051. doi:10.7150/thno.7866
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD, Chief, Laboratory of Molecular Imaging and Nanomedicine, NIBIB, NIH*
* Dr. Chen is serving in his personal capacity.
Editor-in-chief profile
new Impact factor is 7.827, up from the previous 7.806. Congratulation!
new NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
new Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Special Issue - Translational Theranostics. Guest editor: Tony Y. Hu, PhD, Cornell University.
Published Special Issues