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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.

Latest articles:


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Research Paper
Near Infrared Photoimmunotherapy in the Treatment of Pleural Disseminated NSCLC: Preclinical Experience
Kazuhide Sato, Tadanobu Nagaya, Peter L. Choyke, Hisataka Kobayashi
Theranostics 2015; 5(7): 698-709. doi:10.7150/thno.11559
[Abstract] [Full text] [PDF]


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Review
Lymphatic Imaging: Focus on Imaging Probes
Gang Niu, Xiaoyuan Chen
Theranostics 2015; 5(7): 686-697. doi:10.7150/thno.11862
[Abstract] [Full text] [PDF]


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Research Paper
Characterization of Magnetic Viral Complexes for Targeted Delivery in Oncology
Isabella Almstätter, Olga Mykhaylyk, Marcus Settles, Jennifer Altomonte, Michaela Aichler, Axel Walch, Ernst J. Rummeny, Oliver Ebert, Christian Plank, Rickmer Braren
Theranostics 2015; 5(7): 667-685. doi:10.7150/thno.10438
[Abstract] [Full text] [PDF]


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Research Paper
CYLD Regulates Noscapine Activity in Acute Lymphoblastic Leukemia via a Microtubule-Dependent Mechanism
Yunfan Yang, Jie Ran, Lei Sun, Xiaodong Sun, Youguang Luo, Bing Yan, Tala, Min Liu, Dengwen Li, Lei Zhang, Gang Bao, Jun Zhou
Theranostics 2015; 5(7): 656-666. doi:10.7150/thno.10844
[Abstract] [Full text] [PDF]


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Research Paper
3D Porous Calcium-Alginate Scaffolds Cell Culture System Improved Human Osteoblast Cell Clusters for Cell Therapy
Ching-Yun Chen, Cherng-Jyh Ke, Ko-Chung Yen, Hui-Chen Hsieh, Jui-Sheng Sun, Feng-Huei Lin
Theranostics 2015; 5(6): 643-655. doi:10.7150/thno.11372
[Abstract] [Full text] [PDF]


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Research Paper
Theranostic Mesoporous Silica Nanoparticles Biodegrade after Pro-Survival Drug Delivery and Ultrasound/Magnetic Resonance Imaging of Stem Cells
Paul J. Kempen, Sarah Greasley, Kelly A. Parker, Jos C. Campbell, Huan-Yu Chang, Julian R. Jones, Robert Sinclair, Sanjiv S. Gambhir, Jesse V. Jokerst
Theranostics 2015; 5(6): 631-642. doi:10.7150/thno.11389
[Abstract] [Full text] [PDF]


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Research Paper
Disclosing the CXCR4 Expression in Lymphoproliferative Diseases by Targeted Molecular Imaging
Hans Jürgen Wester, Ulrich Keller, Margret Schottelius, Ambros Beer, Kathrin Philipp-Abbrederis, Frauke Hoffmann, Jakub Šimeček, Carlos Gerngross, Michael Lassmann, Ken Herrmann, Natalia Pellegata, Martina Rudelius, Horst Kessler, Markus Schwaiger
Theranostics 2015; 5(6): 618-630. doi:10.7150/thno.11251
[Abstract] [Full text] [PDF]


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Research Paper
Charge and Hydrophobicity Effects of NIR Fluorophores on Bone-Specific Imaging
Kai Bao, Khaled A. Nasr, Hoon Hyun, Jeong Heon Lee, Julien Gravier, Summer L. Gibbs, Hak Soo Choi
Theranostics 2015; 5(6): 609-617. doi:10.7150/thno.11222
[Abstract] [Full text] [PDF]


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Research Paper
Molecular Imaging of Tumor-Infiltrating Macrophages in a Preclinical Mouse Model of Breast Cancer
Xianlei Sun, Duo Gao, Liquan Gao, Chenran Zhang, Xinhe Yu, Bing Jia, Fan Wang, Zhaofei Liu
Theranostics 2015; 5(6): 597-608. doi:10.7150/thno.11546
[Abstract] [Full text] [PDF]


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Research Paper
Zwitterionic Poly(carboxybetaine)-based Cationic Liposomes for Effective Delivery of Small Interfering RNA Therapeutics without Accelerated Blood Clearance Phenomenon
Yan Li, Ruiyuan Liu, Yuanjie Shi, Zhenzhong Zhang, Xin Zhang
Theranostics 2015; 5(6): 583-596. doi:10.7150/thno.11234
[Abstract] [Full text] [PDF]


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Review
Molecular Imaging of Apoptosis: From Micro to Macro
Wenbin Zeng, Xiaobo Wang, Pengfei Xu, Gang Liu, Henry S. Eden, Xiaoyuan Chen
Theranostics 2015; 5(6): 559-582. doi:10.7150/thno.11548
[Abstract] [Full text] [PDF]


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Review
Radionuclide Imaging of Neurohormonal System of the Heart
Xinyu Chen, Rudolf A. Werner, Mehrbod S. Javadi, Yoshifumi Maya, Michael Decker, Constantin Lapa, Ken Herrmann, Takahiro Higuchi
Theranostics 2015; 5(6): 545-558. doi:10.7150/thno.10900
[Abstract] [Full text] [PDF]


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Review
Theranostic Impact of NG2/CSPG4 Proteoglycan in Cancer
Pier Andrea Nicolosi, Alice Dallatomasina, Roberto Perris
Theranostics 2015; 5(5): 530-544. doi:10.7150/thno.10824
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
Molecular Magnetic Resonance Imaging of Angiogenesis In Vivo using Polyvalent Cyclic RGD-Iron Oxide Microparticle Conjugates
Stavros Melemenidis, Andrew Jefferson, Neil Ruparelia, Asim M Akhtar, Jin Xie, Danny Allen, Alastair Hamilton, James R Larkin, Francisco Perez-Balderas, Sean C Smart, Ruth J Muschel, Xiaoyuan Chen, Nicola R Sibson, Robin P Choudhury
Theranostics 2015; 5(5): 515-529. doi:10.7150/thno.10319
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
Autoregulation of Inducible Nitric Oxide Synthase Expression by RNA Interference Provides Neuroprotection in Neonatal Rats
Zhi Wang, Chenzhuo Feng, Huijuan Zhao, Xiaoyan Ren, Shuling Peng, Zhiyi Zuo
Theranostics 2015; 5(5): 504-514. doi:10.7150/thno.10441
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
Magnetoliposomes Loaded with Poly-Unsaturated Fatty Acids as Novel Theranostic Anti-Inflammatory Formulations
Daniel Calle, Viviana Negri, Paloma Ballesteros, Sebastián Cerdán
Theranostics 2015; 5(5): 489-503. doi:10.7150/thno.10069
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD, Chief, Laboratory of Molecular Imaging and Nanomedicine, NIBIB, NIH*
* Dr. Chen is serving in his personal capacity.
Editor-in-chief profile
new Impact factor is 7.827, up from the previous 7.806. Congratulation!

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Most Cited Paper Award: Winners of this year are Mi Kyung Yu, Jinho Park, Sangyong Jon. A certificate and $US 1000 have been issued. Details ...
new NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
new Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Published Special Issues