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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.

Latest articles:


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Research Paper
Photostimulable Near-Infrared Persistent Luminescent Nanoprobes for Ultrasensitive and Longitudinal Deep-Tissue Bio-Imaging
Yen-Jun Chuang, Zipeng Zhen, Fan Zhang, Feng Liu, Jyoti P. Mishra, Wei Tang, Hongmin Chen, Xinglu Huang, Lianchun Wang, Xiaoyuan Chen, Jin Xie, Zhengwei Pan
Theranostics 2014; 4(11): 1112-1122. doi:10.7150/thno.9710
[Abstract] [Full text] [PDF]


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Research Paper
Co-delivery of Doxorubicin and Bmi1 siRNA by Folate Receptor Targeted Liposomes Exhibits Enhanced Anti-Tumor Effects in vitro and in vivo
Tan Yang, Bin Li, ShiBo Qi, Yong Liu, Yongkang Gai, Peng Ye, Guang Yang, Wendian Zhang, Peng Zhang, Xingxing He, Weijie Li, Zhiping Zhang, Guangya Xiang, Chuanrui Xu
Theranostics 2014; 4(11): 1096-1111. doi:10.7150/thno.9423
[Abstract] [Full text] [PDF]


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Research Paper
Enhancing Therapeutic Effects of Docetaxel-Loaded Dendritic Copolymer Nanoparticles by Co-Treatment with Autophagy Inhibitor on Breast Cancer
Xudong Zhang, Ying Yang, Xin Liang, Xiaowei Zeng, Zhigang Liu, Wei Tao, Xiaojun Xiao, Hongbo Chen, Laiqiang Huang, Lin Mei
Theranostics 2014; 4(11): 1085-1095. doi:10.7150/thno.9933
[Abstract] [Full text] [PDF]


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Review
Intraoperative Imaging-Guided Cancer Surgery: From Current Fluorescence Molecular Imaging Methods to Future Multi-Modality Imaging Technology
Chongwei Chi, Yang Du, Jinzuo Ye, Deqiang Kou, Jingdan Qiu, Jiandong Wang, Jie Tian, Xiaoyuan Chen
Theranostics 2014; 4(11): 1072-1084. doi:10.7150/thno.9899
[Abstract] [Full text] [PDF]


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Research Paper
Multiparametric Spectroscopic Photoacoustic Imaging of Breast Cancer Development in a Transgenic Mouse Model
Katheryne E. Wilson, Sunitha V. Bachawal, Lu Tian, Jürgen K. Willmann
Theranostics 2014; 4(11): 1062-1071. doi:10.7150/thno.9922
[Abstract] [Full text] [PDF]


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Research Paper
Microtubule-Associated Protein Mdp3 Promotes Breast Cancer Growth and Metastasis
Tala, Songbo Xie, Xiaodong Sun, Xiaoou Sun, Jie Ran, Linlin Zhang, Dengwen Li, Min Liu, Gang Bao, Jun Zhou
Theranostics 2014; 4(10): 1052-1061. doi:10.7150/thno.9727
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
Megalin-Mediated Specific Uptake of Chitosan/siRNA Nanoparticles in Mouse Kidney Proximal Tubule Epithelial Cells Enables AQP1 Gene Silencing
Shan Gao, San Hein, Frederik Dagnæs-Hansen, Kathrin Weyer, Chuanxu Yang, Rikke Nielsen, Erik I Christensen, Robert A Fenton, Jørgen Kjems
Theranostics 2014; 4(10): 1039-1051. doi:10.7150/thno.7866
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
India Ink Incorporated Multifunctional Phase-transition Nanodroplets for Photoacoustic/Ultrasound Dual-modality Imaging and Photoacoustic Effect Based Tumor Therapy
Jia Jian, Chengbo Liu, Yuping Gong, Lei Su, Bin Zhang, Zhigang Wang, Dong wang, Yu Zhou, Fenfen Xu, Pan Li, Yuanyi Zheng, Liang Song, Xiyuan Zhou
Theranostics 2014; 4(10): 1026-1038. doi:10.7150/thno.9754
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
Contrast-Enhanced Ultrasound Imaging for the Detection of Focused Ultrasound-Induced Blood-Brain Barrier Opening
Ching-Hsiang Fan, Wun-Hao Lin, Chien-Yu Ting, Wen-Yen Chai, Tzu-Chen Yen, Hao-Li Liu, Chih-Kuang Yeh
Theranostics 2014; 4(10): 1014-1025. doi:10.7150/thno.9575
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
FMN-Coated Fluorescent USPIO for Cell Labeling and Non-Invasive MR Imaging in Tissue Engineering
Marianne E. Mertens, Julia Frese, Deniz Ali Bölükbas, Ladislav Hrdlicka, Susanne Golombek, Sabine Koch, Petra Mela, Stefan Jockenhövel, Fabian Kiessling, Twan Lammers
Theranostics 2014; 4(10): 1002-1013. doi:10.7150/thno.8763
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Review
Molecular Imaging in Tracking Tumor-Specific Cytotoxic T Lymphocytes (CTLs)
Zhiyi Liu, Zheng Li
Theranostics 2014; 4(10): 990-1001. doi:10.7150/thno.9268
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
Longitudinal Monitoring of Stem Cell Grafts In Vivo Using Magnetic Resonance Imaging with Inducible Maga as a Genetic Reporter
In K. Cho, Sean P. Moran, Ramesh Paudyal, Karolina Piotrowska-Nitsche, Pei-Hsun Cheng, Xiaodong Zhang, Hui Mao, Anthony W.S. Chan
Theranostics 2014; 4(10): 972-989. doi:10.7150/thno.9436
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
Absorption Reconstruction Improves Biodistribution Assessment of Fluorescent Nanoprobes Using Hybrid Fluorescence-mediated Tomography
Felix Gremse, Benjamin Theek, Sijumon Kunjachan, Wiltrud Lederle, Alessa Pardo, Stefan Barth, Twan Lammers, Uwe Naumann, Fabian Kiessling
Theranostics 2014; 4(10): 960-971. doi:10.7150/thno.9293
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Short Research Communication
Hair Metabolomics: Identification of Fetal Compromise Provides Proof of Concept for Biomarker Discovery
Karolina Sulek, Ting-Li Han, Silas Granato Villas-Boas, David Scott Wishart, Shu-E Soh, Kenneth Kwek, Peter David Gluckman, Yap-Seng Chong, Louise Claire Kenny, Philip Newton Baker
Theranostics 2014; 4(9): 953-959. doi:10.7150/thno.9265
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
Specific and Sensitive Tumor Imaging Using Biostable Oligonucleotide Aptamer Probes
Zihua Zeng, Parag Parekh, Zheng Li, Zheng-Zheng Shi, Ching-Hsuan Tung, Youli Zu
Theranostics 2014; 4(9): 945-952. doi:10.7150/thno.9246
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Review
Progress in Aptamer-Mediated Drug Delivery Vehicles for Cancer Targeting and Its Implications in Addressing Chemotherapeutic Challenges
Jie Zhu, He Huang, Shiwu Dong, Liang Ge, Yuan Zhang
Theranostics 2014; 4(9): 931-944. doi:10.7150/thno.9663
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD, Chief, Laboratory of Molecular Imaging and Nanomedicine, NIBIB, NIH*
* Dr. Chen is serving in his personal capacity.
Editor-in-chief profile
new Impact factor is 7.827, up from the previous 7.806. Congratulation!
new NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
new Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Special Issue - Translational Theranostics. Guest editor: Tony Y. Hu, PhD, Cornell University.
Published Special Issues