Cover image

Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.

Latest articles:


toc.jpg

Research Paper
Deficiency of ATP6V1H Causes Bone Loss by Inhibiting Bone Resorption and Bone Formation through the TGF-β1 Pathway
Xiaohong Duan, Jin Liu, Xueni Zheng, Zhe Wang, Yanli Zhang, Ying Hao, Tielin Yang, Hongwen Deng
Theranostics 2016; 6(12): 2183-2195. doi:10.7150/thno.17140
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Versatile pH-response Micelles with High Cell-Penetrating Helical Diblock Copolymers for Photoacoustic Imaging Guided Synergistic Chemo-Photothermal Therapy
Shengyu Shi, Yajing Liu, Yu Chen, Zhihuang Zhang, Yunsheng Ding, Zongquan Wu, Jun Yin, Liming Nie
Theranostics 2016; 6(12): 2170-2182. doi:10.7150/thno.16633
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Early Diagnosis of Brain Metastases Using a Biofluids-Metabolomics Approach in Mice
James R. Larkin, Alex M. Dickens, Timothy D. W. Claridge, Claire Bristow, Kleopatra Andreou, Daniel C. Anthony, Nicola R. Sibson
Theranostics 2016; 6(12): 2161-2169. doi:10.7150/thno.16538
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
A New Concept of Enhancing Immuno-Chemotherapeutic Effects Against B16F10 Tumor via Systemic Administration by Taking Advantages of the Limitation of EPR Effect
Yuting Yang, Xiaowei Tai, Kairong Shi, Shaobo Ruan, Yue Qiu, Zhirong Zhang, Bing Xiang, Qin He
Theranostics 2016; 6(12): 2141-2160. doi:10.7150/thno.16184
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Proto-Oncogenic Src Phosphorylates EB1 to Regulate the Microtubule-Focal Adhesion Crosstalk and Stimulate Cell Migration
Yijun Zhang, Youguang Luo, Rui Lyu, Jie Chen, Ruming Liu, Dengwen Li, Min Liu, Jun Zhou
Theranostics 2016; 6(12): 2129-2140. doi:10.7150/thno.16356
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Gelatin-based Hydrogel Degradation and Tissue Interaction in vivo: Insights from Multimodal Preclinical Imaging in Immunocompetent Nude Mice
Christoph Tondera, Sandra Hauser, Anne Krüger-Genge, Friedrich Jung, Axel T. Neffe, Andreas Lendlein, Robert Klopfleisch, Jörg Steinbach, Christin Neuber, Jens Pietzsch
Theranostics 2016; 6(12): 2114-2128. doi:10.7150/thno.16614
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Intracellular Trafficking Network of Protein Nanocapsules: Endocytosis, Exocytosis and Autophagy
Jinxie Zhang, Xudong Zhang, Gan Liu, Danfeng Chang, Xin Liang, Xianbing Zhu, Wei Tao, Lin Mei
Theranostics 2016; 6(12): 2099-2113. doi:10.7150/thno.16587
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Optimization of Early Response Monitoring and Prediction of Cancer Antiangiogenesis Therapy via Noninvasive PET Molecular Imaging Strategies of Multifactorial Bioparameters
Xiao Bao, Ming-Wei Wang, Jian-Min Luo, Si-Yang Wang, Yong-Ping Zhang, Ying-Jian Zhang
Theranostics 2016; 6(12): 2084-2098. doi:10.7150/thno.13917
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Crucial Role of miR-433 in Regulating Cardiac Fibrosis
Lichan Tao, Yihua Bei, Ping Chen, Zhiyong Lei, Siyi Fu, Haifeng Zhang, Jiahong Xu, Lin Che, Xiongwen Chen, Joost PG Sluijter, Saumya Das, Dragos Cretoiu, Bin Xu, Jiuchang Zhong, Junjie Xiao, Xinli Li
Theranostics 2016; 6(12): 2068-2083. doi:10.7150/thno.15007
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Blocking the 4-1BB Pathway Ameliorates Crystalline Silica-induced Lung Inflammation and Fibrosis in Mice
Chao Li, Sitong Du, Yiping Lu, Xiaowei Lu, Fangwei Liu, Ying Chen, Dong Weng, Jie Chen
Theranostics 2016; 6(12): 2052-2067. doi:10.7150/thno.16180
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Size Dependent Kinetics of Gold Nanorods in EPR Mediated Tumor Delivery
Xiao Tong, Zhantong Wang, Xiaolian Sun, Jibin Song, Orit Jacobson, Gang Niu, Dale O. Kiesewetter, Xiaoyuan Chen
Theranostics 2016; 6(12): 2039-2051. doi:10.7150/thno.17098
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Optical Imaging of Mesenchymal Epithelial Transition Factor (MET) for Enhanced Detection and Characterization of Primary and Metastatic Hepatic Tumors
Shadi A. Esfahani, Pedram Heidari, Sun A. Kim, Shuji Ogino, Umar Mahmood
Theranostics 2016; 6(12): 2028-2038. doi:10.7150/thno.15718
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Activation of GLP-1 Receptor Enhances Neuronal Base Excision Repair via PI3K-AKT-Induced Expression of Apurinic/Apyrimidinic Endonuclease 1
Jenq-Lin Yang, Wei-Yu Chen, Yin-Ping Chen, Chao-Ying Kuo, Shang-Der Chen
Theranostics 2016; 6(12): 2015-2027. doi:10.7150/thno.15993
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Magnetic Enrichment of Dendritic Cell Vaccine in Lymph Node with Fluorescent-Magnetic Nanoparticles Enhanced Cancer Immunotherapy
Honglin Jin, Yuan Qian, Yanfeng Dai, Sha Qiao, Chuan Huang, Lisen Lu, Qingming Luo, Jing Chen, Zhihong Zhang
Theranostics 2016; 6(11): 2000-2014. doi:10.7150/thno.15102
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Specific Inhibition of DNMT3A/ISGF3γ Interaction Increases the Temozolomide Efficiency to Reduce Tumor Growth
Mathilde Cheray, Romain Pacaud, Arulraj Nadaradjane, Lisa Oliver, François M Vallette, Pierre-François Cartron
Theranostics 2016; 6(11): 1988-1999. doi:10.7150/thno.9150
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Reversal of Vascular Calcification and Aneurysms in a Rat Model Using Dual Targeted Therapy with EDTA- and PGG-Loaded Nanoparticles
Nasim Nosoudi, Aniqa Chowdhury, Steven Siclari, Saketh Karamched, Vaideesh Parasaram, Joe Parrish, Patrick Gerard, Narendra Vyavahare
Theranostics 2016; 6(11): 1975-1987. doi:10.7150/thno.16547
[Abstract] [Full text] [PDF]

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD, Chief, Laboratory of Molecular Imaging and Nanomedicine, NIBIB, NIH*
* Dr. Chen is serving in his personal capacity.
Editor-in-chief profile
new Impact factor is 8.854, according to 2016 release of Journal Citation Reports®. Congratulations!

Cover image
Most Cited Paper Award for year 2015: Winners of this year are Chao Wang, Liang Cheng, Zhuang Liu, for the paper "Upconversion Nanoparticles for Photodynamic Therapy and Other Cancer Therapeutics". Details ...
Theme Issue on “Stem Cell Theranostics. Guest Editors: Kristopher Kilian, PhD, and Deok-Ho Kim, PhD
Theme Issue on “Biomolecular and biomimetic materials for theranostics. Guest Editors: Haiyun Song, PhD, and Chunhai Fan, PhD
Theme Issue on “Translational theranostics for infectious diseases. Guest Editor: Dr. Tony Y. Hu, Houston Methodist Research Institute
Theme Issue on “Light-Mediated Deep-Tissue Theranostics. Guest Editors: Dr. Gang Han, University of Massachusetts Medical School, and Dr. Jin Xie, University of Georgia
new Congratulations to Dr. Chen for receiving the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.
NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Published Special Issues