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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.

Latest articles:


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Research Paper
Targeting of Magnetic Nanoparticle-coated Microbubbles to the Vascular Wall Empowers Site-specific Lentiviral Gene Delivery in vivo
Yvonn Heun, Staffan Hildebrand, Alexandra Heidsieck, Bernhard Gleich, Martina Anton, Joachim Pircher, Andrea Ribeiro, Olga Mykhaylyk, Dietmar Eberbeck, Daniela Wenzel, Alexander Pfeifer, Markus Woernle, Florian Krötz, Ulrich Pohl, Hanna Mannell
Theranostics 2017; 7(2): 295-307. doi:10.7150/thno.16192
[Abstract] [Full text] [PDF]


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Research Paper
Visualization, Quantification and Characterization of Caerulein-Induced Acute Pancreatitis in Rats by 3.0T Clinical MRI, Biochemistry and Histomorphology
Ting Yin, Ronald Peeters, Yewei Liu, Yuanbo Feng, Xinyuan Zhang, Yansheng Jiang, Jie Yu, Steven Dymarkowski, Uwe Himmelreich, Raymond Oyen, Yicheng Ni
Theranostics 2017; 7(2): 285-294. doi:10.7150/thno.16282
[Abstract] [Full text] [PDF]


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Research Paper
Nanosized UCMSC-derived extracellular vesicles but not conditioned medium exclusively inhibit the inflammatory response of stimulated T cells: implications for nanomedicine
Marta Monguió-Tortajada, Santiago Roura, Carolina Gálvez-Montón, Josep Maria Pujal, Gemma Aran, Lucía Sanjurjo, Marcel·la Franquesa, Maria-Rosa Sarrias, Antoni Bayes-Genis, Francesc E. Borràs
Theranostics 2017; 7(2): 270-284. doi:10.7150/thno.16154
[Abstract] [Full text] [PDF]


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Research Paper
Enhancing Nanoparticle Accumulation and Retention in Desmoplastic Tumors via Vascular Disruption for Internal Radiation Therapy
Andrew B. Satterlee, Juan D. Rojas, Paul A. Dayton, Leaf Huang
Theranostics 2017; 7(2): 253-269. doi:10.7150/thno.16681
[Abstract] [Full text] [PDF]


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Research Paper
Comprehensive Metaproteomic Analyses of Urine in the Presence and Absence of Neutrophil-Associated Inflammation in the Urinary Tract
Yanbao Yu, Patricia Sikorski, Madeline Smith, Cynthia Bowman-Gholston, Nicolas Cacciabeve, Karen E. Nelson, Rembert Pieper
Theranostics 2017; 7(2): 238-252. doi:10.7150/thno.16086
[Abstract] [Full text] [PDF]


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Research Paper
Comparison of 68Ga-HBED-CC PSMA-PET/CT and multiparametric MRI for gross tumour volume detection in patients with primary prostate cancer based on slice by slice comparison with histopathology
Constantinos Zamboglou, Vanessa Drendel, Cordula A. Jilg, Hans C. Rischke, Teresa I. Beck, Wolfgang Schultze-Seemann, Tobias Krauss, Michael Mix, Florian Schiller, Ulrich Wetterauer, Martin Werner, Mathias Langer, Michael Bock, Philipp T. Meyer, Anca L. Grosu
Theranostics 2017; 7(1): 228-237. doi:10.7150/thno.16638
[Abstract] [Full text] [PDF]


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Research Paper
Genome-Wide lncRNA Microarray Profiling Identifies Novel Circulating lncRNAs for Detection of Gastric Cancer
Kecheng Zhang, Hongzhi Shi, Hongqing Xi, Xiaosong Wu, Jianxin Cui, Yunhe Gao, Wenquan Liang, Chong Hu, Yi Liu, Jiyang Li, Ning Wang, Bo Wei, Lin Chen
Theranostics 2017; 7(1): 213-227. doi:10.7150/thno.16044
[Abstract] [Full text] [PDF]


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Research Paper
[68Ga]Pentixafor-PET/CT for imaging of chemokine receptor CXCR4 expression in multiple myeloma - Comparison to [18F]FDG and laboratory values
Constantin Lapa, Martin Schreder, Andreas Schirbel, Samuel Samnick, Klaus Martin Kortüm, Ken Herrmann, Saskia Kropf, Herrmann Einsele, Andreas K. Buck, Hans-Jürgen Wester, Stefan Knop, Katharina Lückerath
Theranostics 2017; 7(1): 205-212. doi:10.7150/thno.16576
[Abstract] [Full text] [PDF]


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Research Paper
3-D Ultrasound Localization Microscopy for Identifying Microvascular Morphology Features of Tumor Angiogenesis at a Resolution Beyond the Diffraction Limit of Conventional Ultrasound
Fanglue Lin, Sarah E. Shelton, David Espíndola, Juan D. Rojas, Gianmarco Pinton, Paul A. Dayton
Theranostics 2017; 7(1): 196-204. doi:10.7150/thno.16899
[Abstract] [Full text] [PDF]


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Research Paper
Exosomes derived from miR-140-5p-overexpressing human synovial mesenchymal stem cells enhance cartilage tissue regeneration and prevent osteoarthritis of the knee in a rat model
Shi-Cong Tao, Ting Yuan, Yue-Lei Zhang, Wen-Jing Yin, Shang-Chun Guo, Chang-Qing Zhang
Theranostics 2017; 7(1): 180-195. doi:10.7150/thno.17133
[Abstract] [Full text] [PDF]


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Research Paper
Smart Cu(II)-aptamer complexes based gold nanoplatform for tumor micro-environment triggered programmable intracellular prodrug release, photodynamic treatment and aggregation induced photothermal therapy of hepatocellular carcinoma
Da Zhang, Aixian Zheng, Juan Li, Ming Wu, Lingjie Wu, Zuwu Wei, Naishun Liao, Xiaolong Zhang, Zhixiong Cai, Huanghao Yang, Gang Liu, Xiaolong Liu, Jingfeng Liu
Theranostics 2017; 7(1): 164-179. doi:10.7150/thno.17099
[Abstract] [Full text] [PDF]


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Research Paper
Mapping Sentinel Lymph Node Metastasis by Dual-probe Optical Imaging
Xiangyu Yang, Zhe Wang, Fuwu Zhang, Guizhi Zhu, Jibin Song, Gao-Jun Teng, Gang Niu, Xiaoyuan Chen
Theranostics 2017; 7(1): 153-163. doi:10.7150/thno.17085
[Abstract] [Full text] [PDF]


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Research Paper
Microbubble gas volume: A unifying dose parameter in blood-brain barrier opening by focused ultrasound
Kang-Ho Song, Alexander C. Fan, Joshua J. Hinkle, Joshua Newman, Mark A. Borden, Brandon K. Harvey
Theranostics 2017; 7(1): 144-152. doi:10.7150/thno.15987
[Abstract] [Full text] [PDF]


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Research Paper
Chromatin Remodeling Factor LSH is Upregulated by the LRP6-GSK3β-E2F1 Axis Linking Reversely with Survival in Gliomas
Desheng Xiao, Jun Huang, Yu Pan, Hao Li, Chunyan Fu, Chao Mao, Yan Cheng, Ying Shi, Ling Chen, Yiqun Jiang, Rui Yang, Yating Liu, Jianhua Zhou, Ya Cao, Shuang Liu, Yongguang Tao
Theranostics 2017; 7(1): 132-143. doi:10.7150/thno.17032
[Abstract] [Full text] [PDF]


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Research Paper
Pre-vascularization Enhances Therapeutic Effects of Human Mesenchymal Stem Cell Sheets in Full Thickness Skin Wound Repair
Lei Chen, Qi Xing, Qiyi Zhai, Mitchell Tahtinen, Fei Zhou, Lili Chen, Yingbin Xu, Shaohai Qi, Feng Zhao
Theranostics 2017; 7(1): 117-131. doi:10.7150/thno.17031
[Abstract] [Full text] [PDF]


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Research Paper
Heparin improves BMSC cell therapy: Anticoagulant treatment by heparin improves the safety and therapeutic effect of bone marrow-derived mesenchymal stem cell cytotherapy
Li Liao, Bingzheng Shi, Heran Chang, Xiaoxia Su, Lichao Zhang, Chunsheng Bi, Yi Shuai, Xiaoyan Du, Zhihong Deng, Yan Jin
Theranostics 2017; 7(1): 106-116. doi:10.7150/thno.16911
[Abstract] [Full text] [PDF]

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD, Chief, Laboratory of Molecular Imaging and Nanomedicine, NIBIB, NIH*
* Dr. Chen is serving in his personal capacity.
Editor-in-chief profile
new Impact factor is 8.854, according to 2016 release of Journal Citation Reports®. Congratulations!

Cover image
Most Cited Paper Award for year 2015: Winners of this year are Chao Wang, Liang Cheng, Zhuang Liu, for the paper "Upconversion Nanoparticles for Photodynamic Therapy and Other Cancer Therapeutics". Details ...
Theme Issue on “Stem Cell Theranostics. Guest Editors: Kristopher Kilian, PhD, and Deok-Ho Kim, PhD
Theme Issue on “Biomolecular and biomimetic materials for theranostics. Guest Editors: Haiyun Song, PhD, and Chunhai Fan, PhD
Theme Issue on “Translational theranostics for infectious diseases. Guest Editor: Dr. Tony Y. Hu, Houston Methodist Research Institute
Theme Issue on “Light-Mediated Deep-Tissue Theranostics. Guest Editors: Dr. Gang Han, University of Massachusetts Medical School, and Dr. Jin Xie, University of Georgia
new Congratulations to Dr. Chen for receiving the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.
NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Published Special Issues