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Volume 13 (15); 2023

Research Papers

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PET imaging of focused-ultrasound enhanced delivery of AAVs into the murine brain
Javier Ajenjo, Jai Woong Seo, Josquin Foiret, Bo Wu, Marina Nura Raie, James Wang, Brett Zain Fite, Nisi Zhang, Rim Malek, Corinne Beinat, Noeen Malik, David Alexander Anders, Katherine W. Ferrara
Theranostics 2023; 13(15): 5151-5169. doi:10.7150/thno.85549
Abstract Full text PDF PubMed PMC

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In vivo nanoparticle-based T cell imaging can predict therapy response towards adoptive T cell therapy in experimental glioma
Jessica Hunger, Katharina Schregel, Berin Boztepe, Dennis Alexander Agardy, Verena Turco, Kianush Karimian-Jazi, Ina Weidenfeld, Yannik Streibel, Manuel Fischer, Volker Sturm, Rachel Santarella-Mellwig, Michael Kilian, Kristine Jähne, Katharina Sahm, Wolfgang Wick, Lukas Bunse, Sabine Heiland, Theresa Bunse, Martin Bendszus, Michael Platten, Michael O. Breckwoldt
Theranostics 2023; 13(15): 5170-5182. doi:10.7150/thno.87248
Abstract Full text PDF PubMed PMC

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Upregulated FOXM1 stimulates chondrocyte senescence in Acot12-/-Nudt7-/- double knockout mice
Jinsoo Song, Ee Hyun Kim, Jun-Ho Yang, Donghyeon Kim, Akhmad Irhas Robby, Se-ah Kim, Sung Young Park, Ji Hyun Ryu, Eun-Jung Jin
Theranostics 2023; 13(15): 5207-5222. doi:10.7150/thno.89033
Abstract Full text PDF PubMed PMC

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Fe(III)-Shikonin supramolecular nanomedicines as immunogenic cell death stimulants and multifunctional immunoadjuvants for tumor vaccination
Wenjie Feng, Wanrui Shi, Yanqi Cui, Jiajun Xu, Shuwei Liu, Hang Gao, Shoujun Zhu, Yi Liu, Hao Zhang
Theranostics 2023; 13(15): 5266-5289. doi:10.7150/thno.81650
Abstract Full text PDF PubMed PMC

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1α,25(OH)2D3 ameliorates insulin resistance by alleviating γδ T cell inflammation via enhancing fructose-1,6-bisphosphatase 1 expression
Peng Li, Ke Li, Wenhui Yuan, Yuqi Xu, Ping Li, Ruan Wu, Jingru Han, Zhinan Yin, Ligong Lu, Yunfei Gao
Theranostics 2023; 13(15): 5290-5304. doi:10.7150/thno.84645
Abstract Full text PDF PubMed PMC

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Universal theranostic CRISPR/Cas13a RNA-editing system for glioma
Ye Wu, Yunfei Wang, Junhu Zhou, Jianhao Wang, Qi Zhan, Qixue Wang, Eryan Yang, Weili Jin, Fei Tong, Jixing Zhao, Biao Hong, Junrui Liu, Chunsheng Kang
Theranostics 2023; 13(15): 5305-5321. doi:10.7150/thno.84429
Abstract Full text PDF PubMed PMC

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Tet1 deficiency exacerbates oxidative stress in acute kidney injury by regulating superoxide dismutase
Yu Fan, Yangmian Yuan, Mingrui Xiong, Muchuan Jin, Donge Zhang, Dong Yang, Chengyu Liu, Robert B. Petersen, Kun Huang, Anlin Peng, Ling Zheng
Theranostics 2023; 13(15): 5348-5364. doi:10.7150/thno.87416
Abstract Full text PDF PubMed PMC

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Photocurable injectable Janus hydrogel with minimally invasive delivery for all-in-one treatment of gastric perforations and postoperative adhesions
Xiaoqi Wu, Zihan Wang, Jie Xu, Liu Yu, Maoyu Qin, Jianfeng Li, Sitian Liu, Weihan Zheng, Zeyu Li, Jun Ouyang, Yanbing Li, Guoxin Li, Ling Wang, Wenhua Huang, Yaobin Wu
Theranostics 2023; 13(15): 5365-5385. doi:10.7150/thno.87639
Abstract Full text PDF PubMed PMC

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Piezo1 specific deletion in macrophage protects the progression of liver fibrosis in mice
Shangfei Luo, Xiaoduo Zhao, Jintao Jiang, Bo Deng, Silin Liu, Honglin Xu, Qiaorui Tan, Yu'an Chen, Ziyan Zhang, Xianmei Pan, Rentao Wan, Xiaoting Chen, Youfen Yao, Jing Li
Theranostics 2023; 13(15): 5418-5434. doi:10.7150/thno.86103
Abstract Full text PDF PubMed PMC

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Inhalation of acidic nanoparticles prevents doxorubicin cardiotoxicity through improvement of lysosomal function
Yohan Santin, Karina Formoso, Fraha Haidar, Maria Del Pilar Oreja Fuentes, Florence Bourgailh, Nesrine Hifdi, Karim Hnia, Yosra Doghri, Jessica Resta, Camille Champigny, Séverine Lechevallier, Maximin Détrait, Grégoire Cousin, Malik Bisserier, Angelo Parini, Frank Lezoualc'h, Marc Verelst, Jeanne Mialet-Perez
Theranostics 2023; 13(15): 5435-5451. doi:10.7150/thno.86310
Abstract Full text PDF PubMed PMC

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Systemic delivery of glycosylated-PEG-masked oncolytic virus enhances targeting of antitumor immuno-virotherapy and modulates T and NK cell infiltration
Yuzhi Liang, Bing Wang, Qingjing Chen, Xingyue Fu, Chenwei Jiang, Zhiwen Lin, Qiuyu Zhuang, Yongyi Zeng, Xiaolong Liu, Da Zhang
Theranostics 2023; 13(15): 5452-5468. doi:10.7150/thno.87498
Abstract Full text PDF PubMed PMC

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Engineering CAR-T cells for radiohapten capture in imaging and radioimmunotherapy applications
Keifer Kurtz, Laura Eibler, Megan M. Dacek, Lukas M. Carter, Darren R. Veach, Samantha Lovibond, Emma Reynaud, Sarah Qureshy, Michael R. McDevitt, Christopher Bourne, Sebastien Monette, Blesida Punzalan, Shireen Khayat, Svena Verma, Adam L. Kesner, Nai-Kong V. Cheung, Heiko Schöder, Leah Gajecki, Sarah M. Cheal, Steven M. Larson, David A. Scheinberg, Simone Krebs
Theranostics 2023; 13(15): 5469-5482. doi:10.7150/thno.87489
Abstract Full text PDF PubMed PMC

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Nanobody-mediated SPECT/CT imaging reveals the spatiotemporal expression of programmed death-ligand 1 in response to a CD8+ T cell and iNKT cell activating mRNA vaccine
Thomas Ertveldt, Sofie Meulewaeter, Yannick De Vlaeminck, Oscar Olarte, Katrijn Broos, Serge Van Calenbergh, Stephanie Bourgeois, Joke Deprez, Yves Heremans, Cleo Goyvaerts, Willem Staels, Stefaan De Smedt, Heleen Dewitte, Nick Devoogdt, Marleen Keyaerts, Rein Verbeke, Kurt Barbé, Ine Lentacker, Karine Breckpot
Theranostics 2023; 13(15): 5483-5500. doi:10.7150/thno.85106
Abstract Full text PDF PubMed PMC

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Engineered oncolytic bacteria HCS1 exerts high immune stimulation and safety profiles for cancer therapy
Yujie Sun, Yanxia Guo, Xiaoqing Liu, Jinling Liu, Honglai Sun, Zhongying Li, Min Wen, Sheng-Nan Jiang, Wenzhi Tan, Jin Hai Zheng
Theranostics 2023; 13(15): 5546-5560. doi:10.7150/thno.87340
Abstract Full text PDF PubMed PMC

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Tat-NTS peptide protects neurons against cerebral ischemia-reperfusion injury via ANXA1 SUMOylation in microglia
Huijuan Zhou, Lulu Yan, Hezhou Huang, Xing Li, Qian Xia, Lu Zheng, Bin Shao, Qian Gao, Ning Sun, Jing Shi
Theranostics 2023; 13(15): 5561-5583. doi:10.7150/thno.85390
Abstract Full text PDF PubMed PMC

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Efficient PD-L1 imaging of murine glioblastoma with FUS-aided immunoPET by leveraging FcRn-antibody interaction
Céline Chevaleyre, Anthony Novell, Nicolas Tournier, Ambre Dauba, Steven Dubois, Dimitri Kereselidze, Erwan Selingue, Benoit Jego, Bernard Maillère, Benoit Larrat, Hervé Nozach, Charles Truillet
Theranostics 2023; 13(15): 5584-5596. doi:10.7150/thno.87168
Abstract Full text PDF PubMed PMC

Reviews

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Aptamer-engineered (nano)materials for theranostic applications
Navid Rabiee, Suxiang Chen, Sepideh Ahmadi, Rakesh N. Veedu
Theranostics 2023; 13(15): 5183-5206. doi:10.7150/thno.85419
Abstract Full text PDF PubMed PMC

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Visualizing vasculature and its response to therapy in the tumor microenvironment
Qiaoya Lin, Peter L. Choyke, Noriko Sato
Theranostics 2023; 13(15): 5223-5246. doi:10.7150/thno.84947
Abstract Full text PDF PubMed PMC

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The role of radiolabeling in BNCT tracers for enhanced dosimetry and treatment planning
Sajid Mushtaq, Park Ji Ae, Jung Young Kim, Kyo Chul Lee, Kwang Il Kim
Theranostics 2023; 13(15): 5247-5265. doi:10.7150/thno.88998
Abstract Full text PDF PubMed PMC

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Peptide-drug co-assembling: A potent armament against cancer
Can Wu, Manman Wang, Jinpan Sun, Yongyan Jia, Xiali Zhu, Gaizhi Liu, Yanhui Zhu, Yanbin Guan, Zhenqiang Zhang, Xin Pang
Theranostics 2023; 13(15): 5322-5347. doi:10.7150/thno.87356
Abstract Full text PDF PubMed PMC

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Stimuli-activatable nanomedicine meets cancer theranostics
Haonan Li, Yue Feng, Qiang Luo, Zhiqian Li, Xue Li, Huatian Gan, Zhongwei Gu, Qiyong Gong, Kui Luo
Theranostics 2023; 13(15): 5386-5417. doi:10.7150/thno.87854
Abstract Full text PDF PubMed PMC

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Theranostics with photodynamic therapy for personalized medicine: to see and to treat
Youchao Wang, Johannes Nikodemus Staudinger, Thomas L. Mindt, Gilles Gasser
Theranostics 2023; 13(15): 5501-5544. doi:10.7150/thno.87363
Abstract Full text PDF PubMed PMC

Errata

Long non-coding RNA DANCR stabilizes HIF-1α and promotes metastasis by interacting with NF90/NF45 complex in nasopharyngeal carcinoma: Erratum
Xin Wen, Xu Liu, Yan-Ping Mao, Xiao-Jing Yang, Ya-Qin Wang, Pan-Pan Zhang, Yuan Lei, Xiao-Hong Hong, Qing-Mei He, Jun Ma, Na Liu, Ying-Qin Li
Theranostics 2023; 13(15): 5545. doi:10.7150/thno.89706
Abstract Full text PDF PubMed PMC

Dual inhibition of PFKFB3 and VEGF normalizes tumor vasculature, reduces lactate production, and improves chemotherapy in glioblastoma: insights from protein expression profiling and MRI: Erratum
Junfeng Zhang, Wei Xue, Kai Xu, Liang Yi, Yu Guo, Tian Xie, Haipeng Tong, Bo Zhou, Shunan Wang, Qing Li, Heng Liu, Xiao Chen, Jingqin Fang, Weiguo Zhang
Theranostics 2023; 13(15): 5597-5598. doi:10.7150/thno.92042
Abstract Full text PDF

CXCL12-mediated monocyte transmigration into brain perivascular space leads to neuroinflammation and memory deficit in neuropathic pain: Erratum
Chun-Lin Mai, Zhi Tan, Ya-Nan Xu, Jing-Jun Zhang, Zhen-Hua Huang, Dong Wang, Hui Zhang, Wen-Shan Gui, Jun Zhang, Zhen-Jia Lin, Ying-Tong Meng, Xiao Wei, Ying-Tao Jie, Peter M. Grace, Long-Jun Wu, Li-Jun Zhou, Xian-Guo Liu
Theranostics 2023; 13(15): 5599-5600. doi:10.7150/thno.92433
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