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Volume 9 (17); 2019

Research Papers

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Second line chemotherapy and visceral metastases are associated with poor survival in patients with mCRPC receiving 177Lu-PSMA-617
Katharina Kessel, Robert Seifert, Michael Schäfers, Matthias Weckesser, Katrin Schlack, Martin Boegemann, Kambiz Rahbar
Theranostics 2019; 9(17): 4841-4848. doi:10.7150/thno.35759
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Rapid and Ultrasensitive Quantification of Multiplex Respiratory Tract Infection Pathogen via Lateral Flow Microarray based on SERS Nanotags
Di Zhang, Li Huang, Bing Liu, Qinyu Ge, Jian Dong, Xiangwei Zhao
Theranostics 2019; 9(17): 4849-4859. doi:10.7150/thno.35824
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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HIF-1α/Wnt signaling-dependent control of gene transcription regulates neuronal differentiation of glioblastoma stem cells
Daniele Boso, Elena Rampazzo, Carlo Zanon, Silvia Bresolin, Francesca Maule, Elena Porcù, Alice Cani, Alessandro Della Puppa, Luca Trentin, Giuseppe Basso, Luca Persano
Theranostics 2019; 9(17): 4860-4877. doi:10.7150/thno.35882
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Repurposing Brigatinib for the Treatment of Colorectal Cancer Based on Inhibition of ER-phagy
Zhe Zhang, Wei Gao, Li Zhou, Yan Chen, Siyuan Qin, Lu Zhang, Jiayang Liu, Yujia He, Yunlong Lei, Hai-Ning Chen, Junhong Han, Zong-Guang Zhou, Edouard C. Nice, Changlong Li, Canhua Huang, Xiawei Wei
Theranostics 2019; 9(17): 4878-4892. doi:10.7150/thno.36254
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Modulation of Respiration and Mitochondrial Dynamics by SMAC-Mimetics for Combination Therapy in Chemoresistant Cancer
Judith Hagenbuchner, Herbert Oberacher, Kathrin Arnhard, Ursula Kiechl-Kohlendorfer, Michael J. Ausserlechner
Theranostics 2019; 9(17): 4909-4922. doi:10.7150/thno.33758
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Rapamycin Increases Collateral Circulation in Rodent Brain after Focal Ischemia as detected by Multiple Modality Dynamic Imaging
Jixian Wang, Xiaojie Lin, Zhihao Mu, Fanxia Shen, Linyuan Zhang, Qing Xie, Yaohui Tang, Yongting Wang, Zhijun Zhang, Guo-Yuan Yang
Theranostics 2019; 9(17): 4923-4934. doi:10.7150/thno.32676
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Molecular portraits and trastuzumab responsiveness of estrogen receptor-positive, progesterone receptor-positive, and HER2-positive breast cancer
Shen Zhao, Xi-Yu Liu, Xi Jin, Ding Ma, Yi Xiao, Zhi-Ming Shao, Yi-Zhou Jiang
Theranostics 2019; 9(17): 4935-4945. doi:10.7150/thno.35730
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Integrative multi-omics analysis identifies a prognostic miRNA signature and a targetable miR-21-3p/TSC2/mTOR axis in metastatic pheochromocytoma/paraganglioma
Bruna Calsina, Luis Jaime Castro-Vega, Rafael Torres-Pérez, Lucía Inglada-Pérez, Maria Currás-Freixes, Juan María Roldán-Romero, Veronika Mancikova, Rocío Letón, Laura Remacha, María Santos, Nelly Burnichon, Charlotte Lussey-Lepoutre, Elena Rapizzi, Osvaldo Graña, Cristina Álvarez-Escolá, Aguirre A de Cubas, Javier Lanillos, Alfonso Cordero-Barreal, Ángel M Martínez-Montes, Alexandre Bellucci, Laurence Amar, Fabio Luiz Fernandes-Rosa, María Calatayud, Javier Aller, Cristina Lamas, Júlia Sastre-Marcos, Letizia Canu, Esther Korpershoek, Henri J Timmers, Jacques WM Lenders, Felix Beuschlein, Martin Fassnacht-Capeller, Graeme Eisenhofer, Massimo Mannelli, Fátima Al-Shahrour, Judith Favier, Cristina Rodríguez-Antona, Alberto Cascón, Cristina Montero-Conde, Anne-Paule Gimenez-Roqueplo, Mercedes Robledo
Theranostics 2019; 9(17): 4946-4958. doi:10.7150/thno.35458
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Sex modulates the ApoE ε4 effect on brain tau deposition measured by 18F-AV-1451 PET in individuals with mild cognitive impairment
Min Liu, Manish D Paranjpe, Xin Zhou, Phan Q. Duy, Manu S Goyal, Tammie L.S. Benzinger, Jie Lu, Rongfu Wang, Yun Zhou
Theranostics 2019; 9(17): 4959-4970. doi:10.7150/thno.35366
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Au Hollow Nanorods-Chimeric Peptide Nanocarrier for NIR-II Photothermal Therapy and Real-time Apoptosis Imaging for Tumor Theranostics
Weiyun Zhang, Kai Cai, Xuyu Li, Jin Zhang, Zhaoyu Ma, Mohamed F Foda, Yongli Mu, Xinxin Dai, Heyou Han
Theranostics 2019; 9(17): 4971-4981. doi:10.7150/thno.35560
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Regulating Bcl2L12 expression in mast cells inhibits food allergy
Peng-Yuan Zheng, Xiao-Rui Geng, Jing-Yi Hong, Gui Yang, Jiang-Qi Liu, Li-Hua Mo, Yan Feng, Yuan-Yi Zhang, Tao Liu, Pixin Ran, Zhi-Gang Liu, Ping-Chang Yang
Theranostics 2019; 9(17): 4982-4992. doi:10.7150/thno.34001
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Targeting Mechanics-Induced Fibroblast Activation through CD44-RhoA-YAP Pathway Ameliorates Crystalline Silica-Induced Silicosis
Siyi Li, Chao Li, Yiting Zhang, Xiu He, Xi Chen, Xinning Zeng, Fangwei Liu, Ying Chen, Jie Chen
Theranostics 2019; 9(17): 4993-5008. doi:10.7150/thno.35665
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Multiply clustered gold-based nanoparticles complexed with exogenous pDNA achieve prolonged gene expression in stem cells
Se Won Yi, Ji Sun Park, Hye Jin Kim, Jung Sun Lee, Dae Gyun Woo, Keun-Hong Park
Theranostics 2019; 9(17): 5009-5019. doi:10.7150/thno.34487
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Overcoming EZH2 Inhibitor Resistance by Taxane in PTEN-Mutated Cancer
Linlin Ma, Yuqian Yan, Yang Bai, Yinhui Yang, Yunqian Pan, Xiaokun Gang, R. Jeffrey Karnes, Jun Zhang, Qiubo Lv, Qiang Wu, Haojie Huang
Theranostics 2019; 9(17): 5020-5034. doi:10.7150/thno.34700
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Zwitterionic Polymer-Gated Au@TiO2 Core-Shell Nanoparticles for Imaging-Guided Combined Cancer Therapy
Tao Zheng, Wentao Wang, Fan Wu, Ming Zhang, Jian Shen, Yi Sun
Theranostics 2019; 9(17): 5035-5048. doi:10.7150/thno.35418
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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MRP4 sustains Wnt/β-catenin signaling for pregnancy, endometriosis and endometrial cancer
Jun-Jiang Chen, Zhi-Jie Xiao, Xiaojing Meng, Yan Wang, Mei Kuen Yu, Wen Qing Huang, Xiao Sun, Hao Chen, Yong-Gang Duan, Xiaohua Jiang, Maria Pik Wong, Hsiao Chang Chan, Fei Zou, Ye Chun Ruan
Theranostics 2019; 9(17): 5049-5064. doi:10.7150/thno.32097
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development
Min Zhang, Xueer Wang, Fukun Guo, Qin Jia, Nuyun Liu, Yinghua Chen, Yuan Yan, Mianbo Huang, Huiyi Tang, Ying Deng, Simin Huang, Zhitao Zhou, Lu Zhang, Lin Zhang
Theranostics 2019; 9(17): 5065-5084. doi:10.7150/thno.34014
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Enrichment of CD146+ Adipose-Derived Stem Cells in Combination with Articular Cartilage Extracellular Matrix Scaffold Promotes Cartilage Regeneration
Xu Li, Weimin Guo, Kangkang Zha, Xiaoguang Jing, Mingjie Wang, Yu Zhang, Chunxiang Hao, Shuang Gao, Mingxue Chen, Zhiguo Yuan, Zhenyong Wang, Xueliang Zhang, Shi Shen, Haojiang Li, Bin Zhang, Hai Xian, Yuan Zhang, Xiang Sui, Ling Qin, Jiang Peng, Shuyun Liu, Shibi Lu, Quanyi Guo
Theranostics 2019; 9(17): 5105-5121. doi:10.7150/thno.33904
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Reviews

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CD36 tango in cancer: signaling pathways and functions
Jingchun Wang, Yongsheng Li
Theranostics 2019; 9(17): 4893-4908. doi:10.7150/thno.36037
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Current and Future Imaging Methods for Evaluating Response to Immunotherapy in Neuro-Oncology
Benjamin B. Kasten, Neha Udayakumar, Jianmei W. Leavenworth, Anna M. Wu, Suzanne E. Lapi, Jonathan E. McConathy, Anna G. Sorace, Asim K. Bag, James M. Markert, Jason M. Warram
Theranostics 2019; 9(17): 5085-5104. doi:10.7150/thno.34415
[Abstract] [Full text] [PDF] [PubMed] [PMC]