Online advance articles

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The PROTAC selectively degrading BCL-XL represents a novel Hedgehog pathway inhibitor with capacity of combating resistance to Smoothened inhibitors while sparing bone growth
Shaoqing Zhang, Yue Chen, Zhongli Xu, Jun Yang, Renhong Sun, Juan Wang, Yiming Sun, Biao Jiang, Xiaobao Yang, Wenfu Tan
Theranostics 2022; doi:10.7150/thno.75421; accepted
[Author manuscript]

Artificial Intelligence in Pancreatic Cancer
Bowen Huang, Haoran Huang, Shuting Zhang, Dingyue Zhang, Qingya Shi, Junchao Guo
Theranostics 2022; doi:10.7150/thno.77949; accepted
[Author manuscript]

ERK inactivation enhances stemness of NSCLC cells via promoting Slug-mediated epithelial-to-mesenchymal transition
Shurui Cai, Na Li, Xuetao Bai, Lu Liu, Ananya Banerjee, Kousalya Lavudi, Xiaoli Zhang, Jihe Zhao, Monica Venere, Wenrui Duan, Junran Zhang, Meng X. Welliver, Kai He, Qi-En Wang
Theranostics 2022; doi:10.7150/thno.73099; accepted
[Author manuscript]

Yap1 modulates cardiomyocyte hypertrophy via impaired mitochondrial biogenesis in response to chronic mechanical stress overload
Peng Yue, Yue Zhang, Lei Liu, Kaiyu Zhou, Shutao Xia, Mou Peng, Hualin Yan, Xiaoqiang Tang, Zhan Chen, Donghui Zhang, Junling Guo, William T. Pu, Yuxuan Guo, Yimin Hua, Yifei Li
Theranostics 2022; doi:10.7150/thno.74563; accepted
[Author manuscript]

Self-immolative nanosensitizer for glutathione depletion-assisted sonodynamic therapy
Chan Ho Kim, Dong Gil You, Pramod Kumar E. K., Kyung Hee Han, Wooram Um, Jeongjin Lee, Jae Ah Lee, Jae Min Jung, Heegun Kang, and Jae Hyung Park
Theranostics 2022; doi:10.7150/thno.75007; accepted
[Author manuscript]

Depletion of gut microbiota improves the therapeutic efficacy of cancer nanomedicine
Ray Putra Prajnamitra, Yuan-Yuan Cheng, Chaw Yee Beh, Chien-Yi Lu, Jen-Hao Lin, Shu-Chian Ruan, Sheng-Lun Chen, Hung-Chih Chen, Ruey-Bing Yang, Patrick Ching-Ho Hsieh
Theranostics 2022; doi:10.7150/thno.73873; accepted
[Author manuscript]

Targeting PI4KA sensitizes refractory leukemia to chemotherapy by modulating the ERK/AMPK/OXPHOS axis
Xiuxing Jiang, Xiangtao Huang, Guoxun Zheng, Guanfei Jia, Zhiqiang Li, Xin Ding, Ling Lei, Liang Yuan, Shuangnian Xu and Ning Gao
Theranostics 2022; doi:10.7150/thno.76563; in press
[Author manuscript]

AKR1C3-dependent lipid droplet formation confers hepatocellular carcinoma cell adaptability to targeted therapy
Changqing Wu, Chaoliu Dai, Xinyu Li, Mingju Sun, Hongwei Chu, Qiuhui Xuan, Yalei Yin, Chengnan Fang, Fan Yang, Baofeng Zhao, Ke Cai, Shuijun Zhang, Ran Sun, Guowang Xu, Lihua Zhang, Siyu Sun, Yang Liu
Theranostics 2022; doi:10.7150/thno.74974; accepted
[Author manuscript]

Excretable IR-820 for in vivo NIR-II fluorescence cerebrovascular imaging and photothermal therapy of subcutaneous tumor: Errautm
Zhe Feng, Xiaoming Yu, Minxiao Jiang, Liang Zhu, Yi Zhang, Wei Yang, Wang Xi, Gonghui Li, Jun Qian
Theranostics 2022; doi:10.7150/thno.78444; accepted
[Author manuscript]

A sporadic Alzheimer’s blood-brain barrier model for developing ultrasound-mediated delivery of Aducanumab and anti-Tau antibodies
Joanna M. Wasielewska, Juliana C. S. Chaves, Rebecca L. Johnston, Laura A. Milton, Damián Hernández, Liyu Chen, Jae Song, Wendy Lee, Gerhard Leinenga, Rebecca M. Nisbet, Alice Pébay, Jürgen Götz, Anthony R. White and Lotta E. Oikari
Theranostics 2022; doi:10.7150/thno.72685; in press
[Author manuscript]

Advancing 89Zr-immuno-PET in neuroscience with a bispecific anti-amyloid-beta monoclonal antibody - The choice of chelator is essential
Thomas E. Wuensche, Natascha Stergiou, Iris Mes, Mariska Verlaan, Maxime Schreurs, Esther J. M. Kooijman, Bart Janssen, Albert D. Windhorst, Allan Jensen, Ayodeji A. Asuni, Benny Bang-Andersen, Wissam Beaino, Guus A. M. S. Dongen, Danielle J. Vugts, Amsterdam UMC location Vrije Universiteit Amsterdam, dept Radiology and Nuclear Medicine, De Boelelaan, Amsterdam, The Netherlands Amsterdam Neuroscience, Brain imaging, Amsterdam, The Netherlands Lundbeck AS, Valby, De
Theranostics 2022; doi:10.7150/thno.73509; accepted
[Author manuscript]

Identifying the E2F3-MEX3A-KLF4 signaling axis that sustains cancer cells in undifferentiated and proliferative state
Xu Yang, Guilin Li, Yuhua Tian, Xin Wang, Jiuzhi Xu, Ruiqi Liu, Min Deng, Chunlei Shao, Yuwei Pan, Xi Wu, Mengzhen Li, Chaowei Zhang, Rui Liu, Jun Qin, Chen Zhang, Zhanju Liu, Xin Wu, Maksim V. Plikus, Christopher J. Lengner, Zongheng Zheng, Cong Lv and Zhengquan Yu
Theranostics 2022; doi:10.7150/thno.76619; in press
[Author manuscript]

Addressing antimicrobial resistance with the IDentif.AI platform: rapidly optimizing clinically actionable combination therapy regimens against nontuberculous mycobacteria
Devika Mukherjee, Peter Wang, Lissa Hooi, Vedant Sandhu, Kui You, Agata Blasiak, Edward Kai-Hua Chow, Dean Ho, Pui Lai Rachel Ee
Theranostics 2022; doi:10.7150/thno.73078; in press
[Author manuscript]


Note: The manuscripts in this page haven't been copyedited by the journal and the contents may change before final publication.