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Research Paper Engineered CCR2 positive macrophages coordinate immunoregulation with neural regeneration and matrix remodeling after spinal cord injury Yuqi Zhao, Tao Xie, Yanming Ma, Yuhao Wang, Shenghang Liu, Hui Li, Youjun Liu, Renfeng Liu, Hailiang Xu, Cheng Ju, Weidong Wu, Yifan Wang, Siyuan He, Rongjin Luo, Dageng Huang, Shuaijun Jia, Chunping Hu, Liang Yan, Zhiyuan Wang, Lei Zhu Theranostics 2026; 16(13): 7388-7418. doi:10.7150/thno.134560 Full text PDF


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Research Paper Ion-Responsive Microneedles Delivering Subtype-Specific Mitochondrial Extracellular Vesicles from HEY1⁺ Cardiomyocytes for Cardiac Repair in Bama Minipigs with Myocardial Ischemia–Reperfusion Injury Peng Qu, Jiao Shi, Xue Li, Yao Gu, Jun Liu, Hongyan Zhang, MingZhi Zhou, Cui Ma, Xinghui Li, Wenjie Tian, Qi Liang, Gang Li, Panke Cheng Theranostics 2026; 16(13): 7367-7387. doi:10.7150/thno.123209 Full text PDF


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Review Sonogenetics for precision medicine: from molecular toolkit to clinical translation Xinrui Yu, Min Pu, Ruoli Wang, Haitao Ran Theranostics 2026; 16(13): 7345-7366. doi:10.7150/thno.134803 Full text PDF


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Review Biomechanical signaling of cytoskeleton and membrane reorganization in tumor immune chemotactic migration Qijie Zhao, Keliang Chen, Minglu Zhou, Jing Jin Theranostics 2026; 16(13): 7324-7344. doi:10.7150/thno.134995 Full text PDF


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Research Paper Targeted RNA Therapy Reprograms Fibrotic Macrophages to Reverse Pulmonary Fibrosis Zhimin Song, Jingjing Chen, Jiaying Fan, Tinghong Zhang, Xing Peng, Yao Pan, Yun Zhang, Yaofeng Wang, Jinling Qin, Shu Meng Theranostics 2026; 16(13): 7308-7323. doi:10.7150/thno.132296 Full text PDF


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Research Paper P-glycoprotein 1 as a shared target for resensitizing drug-resistant tumor cells and preventing fibronectin-driven metastasis Li-Tzu Huang, Li-Hsin Cheng, Chin-Ho Kuo, Chin-Yun Cheng, Shane-Rong Sheu, Cheng-Han Yang, Pei-Chu Shih, Yi-Syuan Li, Lin Tseng, Wei-Ting Hsueh, Lyh-Jyh Hao, Hung-Chi Cheng Theranostics 2026; 16(13): 7288-7307. doi:10.7150/thno.131375 Full text PDF

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Issue 10; 2026

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Founding Editor-in-Chief:
Prof. Xiaoyuan (Shawn) Chen, PhD
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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.



Sonogenetics for precision medicine: from molecular toolkit to clinical translation

Sonogenetics is an emerging technology for precise biological modulation. It utilizes ultrasound waves for remote, noninvasive, and spatiotemporally precise functional intervention in target cells genetically engineered for acoustic sensitivity. This review systematically summarizes the three core components comprising sonogenetics: sound-responsive agents for modulating cellular functions, highly efficient vectors for targeted gene delivery, and ...

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