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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.


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Research Paper
USP32 confers cancer cell resistance to YM155 via promoting ER-associated degradation of solute carrier protein SLC35F2
Arun Pandian Chandrasekaran, Kamini Kaushal, Chang-Hwan Park, Kye-Seong Kim, Suresh Ramakrishna
Theranostics 2021; 11(20): 9752-9771. doi:10.7150/thno.63806
[Abstract] [Full text] [PDF]


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Research Paper
Osteoblast-derived EGFL6 couples angiogenesis to osteogenesis during bone repair
Kai Chen, Shijie Liao, Yicheng Li, Haibo Jiang, Yun Liu, Chao Wang, Vincent Kuek, Jacob Kenny, Boxiang Li, Qian Huang, Jianxin Hong, Yan Huang, Shek Man Chim, Jennifer Tickner, Nathan J. Pavlos, Jinmin Zhao, Qian Liu, An Qin, Jiake Xu
Theranostics 2021; 11(20): 9738-9751. doi:10.7150/thno.60902
[Abstract] [Full text] [PDF]


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Research Paper
Practical considerations for quantitative clinical SPECT/CT imaging of alpha particle emitting radioisotopes
Nadia Benabdallah, William Scheve, Nicholas Dunn, Delynn Silvestros, Paul Schelker, Diane Abou, Uday Jammalamadaka, Richard Laforest, Zekun Li, Jonathan Liu, David H. Ballard, Nichole M. Maughan, Hiram Gay, Brian C. Baumann, Robert F. Hobbs, Buck Rogers, Amir Iravani, Abhinav K. Jha, Farrokh Dehdashti, Daniel L. J. Thorek
Theranostics 2021; 11(20): 9721-9737. doi:10.7150/thno.63860
[Abstract] [Full text] [PDF]


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Research Paper
Proteomic analysis of lung cancer cells reveals a critical role of BCAT1 in cancer cell metastasis
Lin Mao, Jin Chen, Xue Lu, Canlin Yang, Yi Ding, Mingming Wang, Yunpeng Zhang, Yuying Tian, Xing Li, Yunyun Fu, Yueying Yang, Yunyun Gu, Fei Gao, Junxing Huang, Lujian Liao
Theranostics 2021; 11(19): 9705-9720. doi:10.7150/thno.61731
[Abstract] [Full text] [PDF]


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Research Paper
Inhibition of tumor progression and M2 microglial polarization by extracellular vesicle-mediated microRNA-124 in a 3D microfluidic glioblastoma microenvironment
Soohyun Hong, Jae Young You, Kyurim Paek, Jubin Park, Su Jin Kang, Eun Hee Han, Nakwon Choi, Seok Chung, Won Jong Rhee, Jeong Ah Kim
Theranostics 2021; 11(19): 9687-9704. doi:10.7150/thno.60851
[Abstract] [Full text] [PDF]


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Research Paper
Tumor microenvironment-based screening repurposes drugs targeting cancer stem cells and cancer-associated fibroblasts
Pei-Jung Lee, Chao-Chi Ho, Hao Ho, Wan-Jiun Chen, Chiu-Hua Lin, Yi-Hua Lai, Yi-Chen Juan, Wen-Chung Chu, Jia-Hua Lee, Sheng-Fang Su, Hsuan-Yu Chen, Jeremy J. W. Chen, Gee-Chen Chang, Ker-Chau Li, Pan-Chyr Yang, Huei-Wen Chen
Theranostics 2021; 11(19): 9667-9686. doi:10.7150/thno.62676
[Abstract] [Full text] [PDF]


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Research Paper
Polyamino acid calcified nanohybrids induce immunogenic cell death for augmented chemotherapy and chemo-photodynamic synergistic therapy
Wei Qiu, Mengyun Liang, Yuan Gao, Xuelian Yang, Xingyao Zhang, Xiaoli Zhang, Peng Xue, Yuejun Kang, Zhigang Xu
Theranostics 2021; 11(19): 9652-9666. doi:10.7150/thno.64354
[Abstract] [Full text] [PDF]


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Research Paper
A novel lncRNA linc-AhRA negatively regulates innate antiviral response in murine microglia upon neurotropic herpesvirus infection
Yiliang Wang, Weisheng Luo, Lianzhou Huang, Ji Xiao, Xiaowei Song, Feng Li, Yuying Ma, Xiaohui Wang, Fujun Jin, Ping Liu, Yexuan Zhu, Kaio Kitazato, Yifei Wang, Zhe Ren
Theranostics 2021; 11(19): 9623-9651. doi:10.7150/thno.64880
[Abstract] [Full text] [PDF]


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Research Paper
Visualization of endogenous p27 and Ki67 reveals the importance of a c-Myc-driven metabolic switch in promoting survival of quiescent cancer cells
Ting La, Song Chen, Tao Guo, Xiao Hong Zhao, Liu Teng, Dandan Li, Michael Carnell, Yuan Yuan Zhang, Yu Chen Feng, Nicole Cole, Alexandra C. Brown, Didi Zhang, Qihan Dong, Jenny Y. Wang, Huixia Cao, Tao Liu, Rick F. Thorne, Feng-Min Shao, Xu Dong Zhang, Lei Jin
Theranostics 2021; 11(19): 9605-9622. doi:10.7150/thno.63763
[Abstract] [Full text] [PDF]


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Research Paper
Lysyl hydroxylase 1 (LH1) deficiency promotes angiotensin II (Ang II)-induced dissecting abdominal aortic aneurysm
Hao Li, Haochen Xu, Hongyan Wen, Hongyue Wang, Ranxu Zhao, Yingying Sun, Congxia Bai, Jiedan Ping, Li Song, Mingyao Luo, Jingzhou Chen
Theranostics 2021; 11(19): 9587-9604. doi:10.7150/thno.65277
[Abstract] [Full text] [PDF]


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Research Paper
The Polo-like kinase 1 inhibitor onvansertib represents a relevant treatment for head and neck squamous cell carcinoma resistant to cisplatin and radiotherapy
Anais Hagege, Damien Ambrosetti, Julien Boyer, Alexandre Bozec, Jérôme Doyen, Emmanuel Chamorey, Xingkang He, Isabelle Bourget, Julie Rousset, Esma Saada, Olivia Rastoin, Julien Parola, Frederic Luciano, Yihai Cao, Gilles Pagès, Maeva Dufies
Theranostics 2021; 11(19): 9571-9586. doi:10.7150/thno.61711
[Abstract] [Full text] [PDF]


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Research Paper
Effects of contrast-enhanced ultrasound treatment on neoadjuvant chemotherapy in breast cancer
Anne Rix, Marion Piepenbrock, Barbara Flege, Saskia von Stillfried, Patrick Koczera, Tatjana Opacic, Nina Simons, Peter Boor, Sven Thoröe-Boveleth, Roel Deckers, Jan-Niklas May, Twan Lammers, Georg Schmitz, Elmar Stickeler, Fabian Kiessling
Theranostics 2021; 11(19): 9557-9570. doi:10.7150/thno.64767
[Abstract] [Full text] [PDF]


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Review
Benefits of functional assays in personalized cancer medicine: more than just a proof-of-concept
Christophe Bounaix Morand du Puch, Mathieu Vanderstraete, Stéphanie Giraud, Christophe Lautrette, Niki Christou, Muriel Mathonnet
Theranostics 2021; 11(19): 9538-9556. doi:10.7150/thno.55954
[Abstract] [Full text] [PDF]


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Research Paper
Glycoproteome remodeling in MLL-rearranged B-cell precursor acute lymphoblastic leukemia
Tiago Oliveira, Mingfeng Zhang, Eun Ji Joo, Hisham Abdel-Azim, Chun-Wei Chen, Lu Yang, Chih-Hsing Chou, Xi Qin, Jianjun Chen, Kathirvel Alagesan, Andreia Almeida, Francis Jacob, Nicolle H Packer, Mark von Itzstein, Nora Heisterkamp, Daniel Kolarich
Theranostics 2021; 11(19): 9519-9537. doi:10.7150/thno.65398
[Abstract] [Full text] [PDF]


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Research Paper
The kinase PDK1 regulates regulatory T cell survival via controlling redox homeostasis
Peiran Feng, Quanli Yang, Liang Luo, Yadong Sun, Wenkai Lv, Shuo Wan, Zerong Guan, Zhiqiang Xiao, Feng Liu, Zehua Li, Zhongjun Dong, Meixiang Yang
Theranostics 2021; 11(19): 9503-9518. doi:10.7150/thno.63992
[Abstract] [Full text] [PDF]


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Research Paper
Neuroprotective effects of minocycline and KML29, a potent inhibitor of monoacylglycerol lipase, in an experimental stroke model: a small-animal positron emission tomography study
Tomoteru Yamasaki, Akiko Hatori, Yiding Zhang, Wakana Mori, Yusuke Kurihara, Masanao Ogawa, Hidekatsu Wakizaka, Jian Rong, Lu Wang, Steven Liang, Ming-Rong Zhang
Theranostics 2021; 11(19): 9492-9502. doi:10.7150/thno.64320
[Abstract] [Full text] [PDF]

More ...

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD
Editor-in-chief profile

new Latest Impact Factor 11.556.

Nanotheranostics is indexed in MEDLINE and PubMed Central ...

Research Paper
Metal-Organic Frameworks for Bioimaging: Strategies and Challenges
Yanfei Liu, Ting Jiang, Zhenbao Liu
Nanotheranostics 2022; 6(2): 143-160. doi:10.7150/ntno.63458
[Abstract] [Full text] [PDF]


Research Paper
Dendrimer-2PMPA selectively blocks upregulated microglial GCPII activity and improves cognition in a mouse model of multiple sclerosis
Kristen R. Hollinger, Anjali Sharma, Carolyn Tallon, Lyndah Lovell, Ajit G. Thomas, Xiaolei Zhu, Robyn Wiseman, Ying Wu, Siva P. Kambhampati, Kevin Liaw, Rishi Sharma, Camilo Rojas, Rana Rais, Sujatha Kannan, Rangaramanujam M. Kannan, Barbara S. Slusher
Nanotheranostics 2022; 6(2): 126-142. doi:10.7150/ntno.63158
[Abstract] [Full text] [PDF]


In Memory
The brightest stars - a tribute to Moritz Kircher
Chrysafis Andreou
Nanotheranostics 2022; 6(1): 121-122. doi:10.7150/ntno.63531
[Abstract] [Full text] [PDF]

Special Issue: Osteoarthritis Theranostics. Guest Editors: Dr. WEN, CHUNYI, Dr. Magali Cucchiarini.
Special Issue: Extracellular vesicles in pathogenesis, diagnosis, or therapeutics of human diseases. Guest Editor: Ming-Lin Liu, Perelman School of Medicine, University of Pennsylvania.
Special Issue: Noble-metal Nanostructures for Theranostics. Guest Editors: Xiaohu Xia, University of Central Florida and Hui Wei, Nanjing University
Special Issue Targeting the Cancer Stem Cells. Guest Editor: Fei Chen, PhD, Professor, Wayne State University
Special Issue Progress in Gene Editing Nanotheranostics. Guest Editors: Gang Han (University of Massachusetts Medical School), Wen Xue (University of Massachusetts Medical School), Qiaobing Xu (Tufts University)
Special Issue Progress in Supramolecular Nanotheranostics. Guest Editors: Xiaoyuan (Shawn) Chen (NIBIB/NIH); Gang Zheng (University of Toronto); Jianjun Cheng (University of Illinois Urbana-Champaign); Yi-Yan Yang (Institute of Bioengineering and Nanotechnology, Singapore)

Congratulations to Dr. Chen for being elected as AIMBE fellow: https://aimbe.org/college-of-fellows/cof-2103/

Dr. Chen was recognized as Selected Highly Prolific Authors  (most published articles in the past 5 years) for 3 ACS journals (ACS Nano, Bioconjugate Chemistry, and Molecular Pharmaceutics). More details: http://journalstars.acs.org/

Dr. Chen received the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.

NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Published Special Issues