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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.


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Review
Copper incorporated biomaterial-based technologies for multifunctional wound repair
Zhenhe Zhang, Hang Xue, Yuan Xiong, Yongtao Geng, Adriana C. Panayi, Samuel Knoedler, Guandong Dai, Mohammad-Ali Shahbazi, Bobin Mi, Gouhui Liu
Theranostics 2024; 14(2): 547-570. doi:10.7150/thno.87193
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Research Paper
Targeted modulation of intestinal epithelial regeneration and immune response in ulcerative colitis using dual-targeting bilirubin nanoparticles
Zewei Zhuo, Kehang Guo, Yujun Luo, Qi Yang, Huihuan Wu, Ruijie Zeng, Rui Jiang, Jingwei Li, Rui Wei, Qizhou Lian, Weihong Sha, Yuliang Feng, Hao Chen
Theranostics 2024; 14(2): 528-546. doi:10.7150/thno.87739
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Research Paper
Exosomes derived from CD271+CD56+ bone marrow mesenchymal stem cell subpopoulation identified by single-cell RNA sequencing promote axon regeneration after spinal cord injury
Yi Sun, Quanbo Liu, Yiming Qin, Yan Xu, Jinyun Zhao, Yong Xie, Chengjun Li, Tian Qin, Yuxin Jin, Liyuan Jiang, Yong Cao, Hongbin Lu, Jianzhong Hu
Theranostics 2024; 14(2): 510-527. doi:10.7150/thno.89008
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Research Paper
Generic design principles for antibody-based tumour necrosis factor (TNF) receptor 2 (TNFR2) agonists with FcγR-independent agonism
Mohamed A. Anany, Stefanie Haack, Isabell Lang, Julia Dahlhoff, Juan Gamboa Vargas, Tim Steinfatt, Lea Päckert, Daniela Weisenberger, Olena Zaitseva, Juliane Medler, Kirstin Kucka, Tengyu Zhang, Tom Van Belle, Luc van Rompaey, Andreas Beilhack, Harald Wajant
Theranostics 2024; 14(2): 496-509. doi:10.7150/thno.84404
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Research Paper
Cerebellar Purkinje cell firing promotes conscious recovery from anesthesia state through coordinating neuronal communications with motor cortex
Jinpiao Zhu, Chang Chen, Xiaodong Liu, Mengying He, Yuanyuan Fang, Li Wang, Junke Jia, Juan Guo, Ziyue Zhao, Chenyi Gao, Jingang He, Chengshi Xu, Fuqiang Xu, Daqing Ma, Jie Wang, Zongze Zhang
Theranostics 2024; 14(2): 480-495. doi:10.7150/thno.89592
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Research Paper
Differential effect of cancer-associated fibroblast-derived extracellular vesicles on cisplatin resistance in oral squamous cell carcinoma via miR-876-3p
Soo Hyun Kang, Su Young Oh, Kah-Young Lee, Heon-Jin Lee, Mee-Seon Kim, Tae-Geon Kwon, Jin-Wook Kim, Sung-Tak Lee, So-Young Choi, Su-Hyung Hong
Theranostics 2024; 14(2): 460-479. doi:10.7150/thno.87329
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Research Paper
Long-term Nephrotoxicity after PRRT: Myth or Reality
Richard P. Baum, Xin Fan, Vivianne Jakobsson, Fei Yu, Christiane Schuchardt, Xiaoyuan Chen, Jingjing Zhang
Theranostics 2024; 14(2): 451-459. doi:10.7150/thno.92487
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Research Paper
Vitamin D binding protein (VDBP) hijacks twist1 to inhibit vasculogenic mimicry in hepatocellular carcinoma
Lu-ning Qin, Heng Zhang, Qing-qing Li, Ting Wu, Shan-bin Cheng, Kai-wen Wang, Yue Shi, Hao-ran Ren, Xue-wu Xing, Cheng Yang, Tao Sun
Theranostics 2024; 14(1): 436-450. doi:10.7150/thno.90322
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Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD
Editor-in-chief profile



Special Issue: Osteoarthritis Theranostics. Guest Editors: Dr. WEN, CHUNYI, Dr. Magali Cucchiarini.


CFP: Special issue on mRNA-based vaccine and therapy. Guest Editors: Guocan Yu (Tsinghua University, China), Qiaobing Xu (Tufts University, USA), Wei Tao (Harvard Medical School, USA)


Rationale: The therapeutic benefits of bilirubin in the treatment of ulcerative colitis (UC) are considerable, whereas the underlying mechanism of bilirubin on UC remains unclear remains unexplored. In addition, the weak hydrophilicity and toxicity have limited its translational applications. Methods: We have developed a colon dual-targeting nanoparticle, for orally delivering bilirubin through hydrogel encapsulation of hyaluronic acid (HA)-modified poly (lactic-co-glycolic acid) (PLGA) nanoparticles (HA-PLGABilirubin). Confocal microscopy and in vivo imaging were used to evaluate the uptake and....
Rationale: Spinal cord injury (SCI) results in neural tissue damage. However, the limited regenerative capacity of adult mammals' axons upon SCI leads to persistent neurological dysfunction. Thus, exploring the pathways that can enhance axon regeneration in injured spinal cord is of great significance. Methods: Through the utilization of single-cell RNA sequencing in this research, a distinct subpopulation of bone marrow mesenchymal stem cells (BMSCs) that exhibits the capacity to facilitate axon regeneration has been discovered. Subsequently, the CD271+CD56+ BMSCs subpopulation was isolated using....

Nanotheranostics is indexed in MEDLINE and PubMed Central ...

Research Paper
Theranostic Phthalocyanine and Naphthalocyanine Nanoparticles for Photoacoustic Imaging and Photothermal Therapy of Tumors
Yiran Tian, Nicole Carrillo-Malani, Kailin Feng, Joann Miller, Theresa M. Busch, Karthik M. Sundaram, Zhiliang Cheng, Ahmad Amirshaghaghi, Andrew Tsourkas
Nanotheranostics 2024; 8(1): 100-111. doi:10.7150/ntno.88892
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