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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.


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Research Paper
Low-dose total body irradiation facilitates antitumoral Th1 immune responses
Dominik Sonanini, Christoph M. Griessinger, Barbara F. Schörg, Philipp Knopf, Klaus Dittmann, Martin Röcken, Bernd J. Pichler, Manfred Kneilling
Theranostics 2021; 11(16): 7700-7714. doi:10.7150/thno.61459
[Abstract] [Full text] [PDF]


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Research Paper
Attenuation of tonic inhibition prevents chronic neurovascular impairments in a Thy1-ChR2 mouse model of repeated, mild traumatic brain injury
James R Mester, Paolo Bazzigaluppi, Adrienne Dorr, Tina Beckett, Matthew Burke, JoAnne McLaurin, John G Sled, Bojana Stefanovic
Theranostics 2021; 11(16): 7685-7699. doi:10.7150/thno.60190
[Abstract] [Full text] [PDF]


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Research Paper
Snail1 expression in endothelial cells controls growth, angiogenesis and differentiation of breast tumors
David Cabrerizo-Granados, Raúl Peña, Laura Palacios, Laura Carrillo-Bosch, Josep Lloreta-Trull, Laura Comerma, Mar Iglesias, Antonio García de Herreros
Theranostics 2021; 11(16): 7671-7684. doi:10.7150/thno.61881
[Abstract] [Full text] [PDF]


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Research Paper
STK39 promotes breast cancer invasion and metastasis by increasing SNAI1 activity upon phosphorylation
Zhaoping Qiu, Bo Dong, Weijie Guo, Rychahou Piotr, Greg Longmore, Xiuwei Yang, Zhiyong Yu, Jiong Deng, B. Mark Evers, Yadi Wu
Theranostics 2021; 11(16): 7658-7670. doi:10.7150/thno.62406
[Abstract] [Full text] [PDF]


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Research Paper
Silencing of METTL3 effectively hinders invasion and metastasis of prostate cancer cells
Yabing Chen, Chun Pan, Xiaotong Wang, Dihui Xu, Yuhan Ma, Jianhang Hu, Peilin Chen, Zou Xiang, Qiu Rao, Xiaodong Han
Theranostics 2021; 11(16): 7640-7657. doi:10.7150/thno.61178
[Abstract] [Full text] [PDF]


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Research Paper
Fiber scaffold bioartificial liver therapy relieves acute liver failure and extrahepatic organ injury in pigs
Jun Weng, Xu Han, Fanhong Zeng, Yue Zhang, Lei Feng, Lei Cai, Kangyan Liang, Shusong Liu, Shao Li, Gongbo Fu, Min Zeng, Yi Gao
Theranostics 2021; 11(16): 7620-7639. doi:10.7150/thno.58515
[Abstract] [Full text] [PDF]


Erratum
Crucial Role of miR-433 in Regulating Cardiac Fibrosis: Erratum
Lichan Tao, Yihua Bei, Ping Chen, Zhiyong Lei, Siyi Fu, Haifeng Zhang, Jiahong Xu, Lin Che, Xiongwen Chen, Joost PG Sluijter, Saumya Das, Dragos Cretoiu, Bin Xu, Jiuchang Zhong, Junjie Xiao, Xinli Li
Theranostics 2021; 11(15): 7618-7619. doi:10.7150/thno.63330
[Abstract] [Full text] [PDF] [PMC]


Erratum
Serum exosomes can restore cellular function in vitro and be used for diagnosis in dysferlinopathy: Erratum
Xue Dong, Xianjun Gao, Yi Dai, Ning Ran, HaiFang Yin
Theranostics 2021; 11(15): 7616-7617. doi:10.7150/thno.62181
[Abstract] [Full text] [PDF] [PMC]


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Research Paper
Elevated IgE promotes cardiac fibrosis by suppressing miR-486a-5p
Hongmei Zhao, Hongqin Yang, Chi Geng, Yang Chen, Yaqin Tang, Zhiwei Li, Junling Pang, Ting Shu, Yu Nie, Yongshuo Liu, Kegang Jia, Jing Wang
Theranostics 2021; 11(15): 7600-7615. doi:10.7150/thno.47845
[Abstract] [Full text] [PDF] [PMC]


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Research Paper
A platelet-mimicking theranostic platform for cancer interstitial brachytherapy
Meng Lyu, Mingzhu Chen, Lujie Liu, Daoming Zhu, Xianjia Wu, Yang Li, Lang Rao, Zhirong Bao
Theranostics 2021; 11(15): 7589-7599. doi:10.7150/thno.61259
[Abstract] [Full text] [PDF] [PMC]


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Research Paper
Lactate dehydrogenase B regulates macrophage metabolism in the tumor microenvironment
Ann-Christin Frank, Rebecca Raue, Dominik C. Fuhrmann, Evelyn Sirait-Fischer, Carsten Reuse, Andreas Weigert, Dieter Lütjohann, Karsten Hiller, Shahzad Nawaz Syed, Bernhard Brüne
Theranostics 2021; 11(15): 7570-7588. doi:10.7150/thno.58380
[Abstract] [Full text] [PDF] [PMC]


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Review
Recent strategies for nano-based PTT combined with immunotherapy: from a biomaterial point of view
Xingyue Huang, Yang Lu, Mingxue Guo, Shouying Du, Ning Han
Theranostics 2021; 11(15): 7546-7569. doi:10.7150/thno.56482
[Abstract] [Full text] [PDF] [PMC]


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Research Paper
Arginine starvation elicits chromatin leakage and cGAS-STING activation via epigenetic silencing of metabolic and DNA-repair genes
Sheng-Chieh Hsu, Chia-Lin Chen, Mei-Ling Cheng, Cheng-Ying Chu, Chun A. Changou, Yen-Ling Yu, Shauh-Der Yeh, Tse-Chun Kuo, Cheng-Chin Kuo, Chih-Pin Chuu, Chien-Feng Li, Lu-Hai Wang, Hong-Wu Chen, Yun Yen, David K. Ann, Hung-Jung Wang, Hsing-Jien Kung
Theranostics 2021; 11(15): 7527-7545. doi:10.7150/thno.54695
[Abstract] [Full text] [PDF] [PMC]


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Research Paper
Circular RNA circRHOBTB3 represses metastasis by regulating the HuR-mediated mRNA stability of PTBP1 in colorectal cancer
Jiaxin Chen, Yizheng Wu, Xin Luo, Dongai Jin, Wei Zhou, Zhenyu Ju, Di Wang, Qing Meng, Huijuan Wang, Xiaotian Fu, Jianbin Xu, Zhangfa Song
Theranostics 2021; 11(15): 7507-7526. doi:10.7150/thno.59546
[Abstract] [Full text] [PDF] [PMC]


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Research Paper
Microbial and genetic-based framework identifies drug targets in inflammatory bowel disease
Zhihan Wang, Kai Guo, Pan Gao, Qinqin Pu, Ping Lin, Shugang Qin, Na Xie, Junguk Hur, Changlong Li, Canhua Huang, Min Wu
Theranostics 2021; 11(15): 7491-7506. doi:10.7150/thno.59196
[Abstract] [Full text] [PDF] [PMC]


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Editorial
Mycobiota dysbiosis and gastric tumorigenesis
Nicolas Papon, Tobias M. Hohl, Bing Zhai
Theranostics 2021; 11(15): 7488-7490. doi:10.7150/thno.61480
[Abstract] [Full text] [PDF] [PMC]

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD
Editor-in-chief profile

new Latest Impact Factor 8.579

Nanotheranostics is indexed in MEDLINE and PubMed Central ...

Research Paper
Photoactive Silver Nanoagents for Backgroundless Monitoring and Precision Killing of Multidrug-Resistant Bacteria
Zhiwen Xu, Cai Zhang, Yunjian Yu, Wenshuai Li, Zhuang Ma, Jingjing Wang, Xinge Zhang, Hongmei Gao, Dingbin Liu
Nanotheranostics 2021; 5(4): 472-487. doi:10.7150/ntno.62364
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Review
Nanotheranostic Application of Fluorescent Protein-Gold Nanocluster Hybrid Materials: A Mini-review
Han Ding, Zhijun Chen
Nanotheranostics 2021; 5(4): 461-471. doi:10.7150/ntno.58060
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Research Paper
Carbohydrate based biomarkers enable hybrid near infrared fluorescence and 64Cu based radio-guidance for improved surgical precision
Wenbo Wang, Anders E. Hansen, Hongmei Sun, Frederikke P. Fliedner, Andreas Kjaer, Andreas I. Jensen, Thomas L. Andresen, Jonas R. Henriksen
Nanotheranostics 2021; 5(4): 448-460. doi:10.7150/ntno.60295
[Abstract] [Full text] [PDF] [PubMed] [PMC]

CFP - Special Issue: Extracellular vesicles in pathogenesis, diagnosis, or therapeutics of human diseases. Guest Editor: Ming-Lin Liu, Perelman School of Medicine, University of Pennsylvania.
Special Issue: Noble-metal Nanostructures for Theranostics. Guest Editors: Xiaohu Xia, University of Central Florida and Hui Wei, Nanjing University
Special Issue Targeting the Cancer Stem Cells. Guest Editor: Fei Chen, PhD, Professor, Wayne State University
Special Issue Progress in Gene Editing Nanotheranostics. Guest Editors: Gang Han (University of Massachusetts Medical School), Wen Xue (University of Massachusetts Medical School), Qiaobing Xu (Tufts University)
Special Issue Progress in Supramolecular Nanotheranostics. Guest Editors: Xiaoyuan (Shawn) Chen (NIBIB/NIH); Gang Zheng (University of Toronto); Jianjun Cheng (University of Illinois Urbana-Champaign); Yi-Yan Yang (Institute of Bioengineering and Nanotechnology, Singapore)

Congratulations to Dr. Chen for being elected as AIMBE fellow: https://aimbe.org/college-of-fellows/cof-2103/

Dr. Chen was recognized as Selected Highly Prolific Authors  (most published articles in the past 5 years) for 3 ACS journals (ACS Nano, Bioconjugate Chemistry, and Molecular Pharmaceutics). More details: http://journalstars.acs.org/

Dr. Chen received the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.

NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Published Special Issues