Research Paper
Shh agonist enhances maturation in homotypic Lgr5-positive inner ear organoids
Nathaniel T Carpena, So-Young Chang, Seyoung Mun, Kyung Wook Kim, Hyun C Yoon, Phil-Sang Chung, Ji-Hun Mo, Jin-Chul Ahn, Ji On Park, Kyudong Han, Ji Eun Choi, Jae Yun Jung, Min Young Lee
Theranostics 2025; 15(12): 5543-5565. doi:10.7150/thno.107345
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Research Paper
Bispecific Siglec-15/T cell antibody (STAB) activates T cells and suppresses pancreatic ductal adenocarcinoma and non-small cell lung tumors in vivo
Limei Shen, Alison Schaefer, Justin Huckaby, Whitney Wolf, Samuel K. Lai
Theranostics 2025; 15(12): 5529-5542. doi:10.7150/thno.103372
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Research Paper
Pilot first-in-human CCR2 PET/CT to detect abdominal aortic aneurysm wall instability
Santiago Elizondo-Benedetto, Deborah Sultan, Ryan Wahidi, Mahdjoub Hamdi, Mohamed S. Zaghloul, Shahab Hafezi, Batool Arif, Laura K. McDonald, Kitty Harrison, Dakkota Thies, Gyu Seong Heo, Hannah Luehmann, Lisa Detering, J. Westley Ohman, Zachary J. Wanken, Luis A. Sanchez, Joseph E. Ippolito, Jie Zheng, Robert J. Gropler, Richard Laforest, Yongjian Liu, Mohamed A. Zayed
Theranostics 2025; 15(12): 5518-5528. doi:10.7150/thno.108656
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Research Paper
Nitric oxide-primed engineered extracellular vesicles restore bioenergetics in acute kidney injury via mitochondrial transfer
Fei Peng, Xiaoniao Chen, Lingling Wu, Jiayi He, Zongjin Li, Quan Hong, Qiang Zhao, Meng Qian, Xu Wang, Wanjun Shen, Tingting Qi, Yiyu Huang, Guangyan Cai, Chuyue Zhang, Xiangmei Chen
Theranostics 2025; 15(11): 5499-5517. doi:10.7150/thno.113741
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Research Paper
BARD1-mediated stabilization of METTL14 promotes retinal neovascularization by m6A-modifying MXD1 mRNA on a YTHDF2-dependent manner
Xianyang Liu, Shuhao Zeng, Jiayu Meng, Qian Zhou, Fan Cao, Baorui Chu, Chao Wu, Yakun Wang, Hui Feng, Xiaorui Bi, Xinyuan Chen, Wenxian Yang, Meng Tian, Hui Yang, Ke Hu, Shengping Hou
Theranostics 2025; 15(11): 5481-5498. doi:10.7150/thno.110122
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Review
Nano drug delivery systems for advanced immune checkpoint blockade therapy
Chenqi Guo, Ling Lin, Yihan Wang, Jing Jing, Qiyong Gong, Kui Luo
Theranostics 2025; 15(11): 5440-5480. doi:10.7150/thno.112475
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Founding Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD
EIC profile
Congratulations! Professor Chen has been elected as a member of the Academia Europaea.
Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.