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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.


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Review
Ferritins as natural and artificial nanozymes for theranostics
Bing Jiang, Long Fang, Kongming Wu, Xiyun Yan, Kelong Fan
Theranostics 2020; 10(2): 687-706. doi:10.7150/thno.39827
[Abstract] [Full text] [PDF]


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Review
Carbon Dots as Potent Antimicrobial Agents
Xiuli Dong, Weixiong Liang, Mohammed J. Meziani, Ya-Ping Sun, Liju Yang
Theranostics 2020; 10(2): 671-686. doi:10.7150/thno.39863
[Abstract] [Full text] [PDF]


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Research Paper
A supramolecular protein chaperone for vaccine delivery
Zhongyan Wang, Yuna Shang, Zhaoqi Tan, Xiaoyan Li, Guoliang Li, Chunhua Ren, Fuqiang Wang, Zhimou Yang, Jianfeng Liu
Theranostics 2020; 10(2): 657-670. doi:10.7150/thno.39132
[Abstract] [Full text] [PDF]


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Research Paper
Rod-shape theranostic nanoparticles facilitate antiretroviral drug biodistribution and activity in human immunodeficiency virus susceptible cells and tissues
Bhavesh D. Kevadiya, Brendan Ottemann, Insiya Z. Mukadam, Laura Castellanos, Kristen Sikora, James R. Hilaire, Jatin Machhi, Jonathan Herskovitz, Dhruvkumar Soni, Mahmudul Hasan, Wenting Zhang, Sarella Anandakumar, Jered Garrison, JoEllyn McMillan, Benson Edagwa, R. Lee Mosley, Richard W. Vachet, Howard E. Gendelman
Theranostics 2020; 10(2): 630-656. doi:10.7150/thno.39847
[Abstract] [Full text] [PDF]


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Research Paper
Supramolecular nanomaterials based on hollow mesoporous drug carriers and macrocycle-capped CuS nanogates for synergistic chemo-photothermal therapy
Jie Yang, Dihua Dai, Xinyue Lou, Lianjun Ma, Bailiang Wang, Ying-Wei Yang
Theranostics 2020; 10(2): 615-629. doi:10.7150/thno.40066
[Abstract] [Full text] [PDF]


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Research Paper
Mdig promotes oncogenic gene expression through antagonizing repressive histone methylation markers
Qian Zhang, Chitra Thakur, Yao Fu, Zhuoyue Bi, Priya Wadgaonkar, Liping Xu, Zhipeng Liu, Wanqing Liu, Jian Wang, Benjamin L. Kidder, Fei Chen
Theranostics 2020; 10(2): 602-614. doi:10.7150/thno.36220
[Abstract] [Full text] [PDF]


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Research Paper
In vivo liposomal delivery of PPARα/γ dual agonist tesaglitazar in a model of obesity enriches macrophage targeting and limits liver and kidney drug effects
Victoria Osinski, Dustin K. Bauknight, Siva Sai Krishna Dasa, Matthew J. Harms, Tobias Kroon, Melissa A. Marshall, James C. Garmey, Anh T. Nguyen, Julia Hartman, Aditi Upadhye, Prasad Srikakulapu, Andrea Zhou, Gavin O'Mahony, Alexander L. Klibanov, Kimberly A. Kelly, Jeremie Boucher, Coleen A. McNamara
Theranostics 2020; 10(2): 585-601. doi:10.7150/thno.36572
[Abstract] [Full text] [PDF]


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Research Paper
Delivery of polymeric nanostars for molecular imaging and endoradiotherapy through the enhanced permeability and retention (EPR) effect
Jeroen A.C.M. Goos, Andrew Cho, Lukas M. Carter, Thomas R. Dilling, Maria Davydova, Komal Mandleywala, Simon Puttick, Abhishek Gupta, William S. Price, John F. Quinn, Michael R. Whittaker, Jason S. Lewis, Thomas P. Davis
Theranostics 2020; 10(2): 567-584. doi:10.7150/thno.36777
[Abstract] [Full text] [PDF]


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Research Paper
NFATc3-dependent expression of miR-153-3p promotes mitochondrial fragmentation in cardiac hypertrophy by impairing mitofusin-1 expression
Tao Wang, Mei Zhai, Sheng Xu, Murugavel Ponnusamy, Yan Huang, Cui-Yun Liu, Man Wang, Chan Shan, Pei-Pei Shan, Xiang-Qian Gao, Kai Wang, Xin-Zhe Chen, Jing Liu, Jing-Yi Xie, De-Yu Zhang, Lu-yu Zhou, Kun Wang
Theranostics 2020; 10(2): 553-566. doi:10.7150/thno.37181
[Abstract] [Full text] [PDF]


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Research Paper
WNT signaling inducing activity in ascites predicts poor outcome in ovarian cancer
Anna Kotrbová, Petra Ovesná, Tomáš Gybel', Tomasz Radaszkiewicz, Markéta Bednaříková, Jitka Hausnerová, Eva Jandáková, Luboš Minář, Igor Crha, Vít Weinberger, Luděk Záveský, Vítězslav Bryja, Vendula Pospíchalová
Theranostics 2020; 10(2): 537-552. doi:10.7150/thno.37423
[Abstract] [Full text] [PDF]


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Research Paper
ANKRD22, a novel tumor microenvironment-induced mitochondrial protein promotes metabolic reprogramming of colorectal cancer cells
Tianhui Pan, Jingwen Liu, Song Xu, Qiao Yu, Hongping Wang, Hongxiang Sun, Jia Wu, Yue Zhu, Jianwei Zhou, Yongliang Zhu
Theranostics 2020; 10(2): 516-536. doi:10.7150/thno.37472
[Abstract] [Full text] [PDF]


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Research Paper
Targeting the STING pathway in tumor-associated macrophages regulates innate immune sensing of gastric cancer cells
Lei Miao, Jingjing Qi, Qi Zhao, Qi-Nian Wu, Da-Liang Wei, Xiao-Li Wei, Jia Liu, Jun Chen, Zhao-Lei Zeng, Huai-Qiang Ju, Hui-yan Luo, Rui-Hua Xu
Theranostics 2020; 10(2): 498-515. doi:10.7150/thno.37745
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Research Paper
A tumor suppressor enhancing module orchestrated by GATA4 denotes a therapeutic opportunity for GATA4 deficient HCC patients
Feng Lu, Qian Zhou, Lu Liu, Guandi Zeng, Weimin Ci, Wanting Liu, Gong Zhang, Zhiyi Zhang, Peng Wang, Aiqun Zhang, Yunfei Gao, Lei Yu, Qingyu He, Liang Chen
Theranostics 2020; 10(2): 484-497. doi:10.7150/thno.38060
[Abstract] [Full text] [PDF]


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Review
Micro/nano-bubble-assisted ultrasound to enhance the EPR effect and potential theranostic applications
Lei Duan, Li Yang, Juan Jin, Fang Yang, Dong Liu, Ke Hu, Qinxin Wang, Yuanbin Yue, Ning Gu
Theranostics 2020; 10(2): 462-483. doi:10.7150/thno.37593
[Abstract] [Full text] [PDF]


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Review
Advances in GLP-1 receptor targeting radiolabeled agent development and prospective of theranostics
Irina Velikyan, Olof Eriksson
Theranostics 2020; 10(1): 437-461. doi:10.7150/thno.38366
[Abstract] [Full text] [PDF]


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Review
Type H blood vessels in bone modeling and remodeling
Yi Peng, Song Wu, Yusheng Li, Janet L. Crane
Theranostics 2020; 10(1): 426-436. doi:10.7150/thno.34126
[Abstract] [Full text] [PDF]

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD
Editor-in-chief profile

newNanotheranostics is indexed in MEDLINE and PubMed Central ...

Research Paper
Nano-Antagonist Alleviates Inflammation and Allows for MRI of Atherosclerosis
Brian Mog, Courteney Asase, Alice Chaplin, Huiyun Gao, Sanjay Rajagopalan, Andrei Maiseyeu
Nanotheranostics 2019; 3(4): 342-355. doi:10.7150/ntno.37391
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Research Paper
Microbubble enhanced ultrasound for the antivascular treatment and monitoring of hepatocellular carcinoma
Julia C. D'Souza, Laith R. Sultan, Stephen J. Hunt, Terence P. Gade, Mrigendra B. Karmacharya, Susan M. Schultz, Angela K. Brice, Andrew K. W. Wood, Chandra M. Sehgal
Nanotheranostics 2019; 3(4): 331-341. doi:10.7150/ntno.39514
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Research Paper
Enhanced blood-brain-barrier penetrability and tumor-targeting efficiency by peptide-functionalized poly(amidoamine) dendrimer for the therapy of gliomas
Changliang Liu, Zijian Zhao, Houqian Gao, Iman Rostami, Qing You, Xinru Jia, Chen Wang, Ling Zhu, Yanlian Yang
Nanotheranostics 2019; 3(4): 311-330. doi:10.7150/ntno.38954
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Research Paper
Theranostic nanoparticles enhance the response of glioblastomas to radiation
Wei Wu, Jessica L. Klockow, Suchismita Mohanty, Kimberly S. Ku, Maryam Aghighi, Stavros Melemenidis, Zixin Chen, Kai Li, Goreti Ribeiro Morais, Ning Zhao, Jürgen Schlegel, Edward E. Graves, Jianghong Rao, Paul M. Loadman, Robert A. Falconer, Sudip Mukherjee, Frederick T. Chin, Heike E. Daldrup-Link
Nanotheranostics 2019; 3(4): 299-310. doi:10.7150/ntno.35342
[Abstract] [Full text] [PDF] [PubMed] [PMC]

new CFP - Special Issue: Noble-metal Nanostructures for Theranostics. Guest Editors: Xiaohu Xia, University of Central Florida and Hui Wei, Nanjing University
Special Issue Targeting the Cancer Stem Cells. Guest Editor: Fei Chen, PhD, Professor, Wayne State University
Special Issue Progress in Critical Reviews of Immunotheranostics. Guest Editors: Xiaoyuan (Shawn) Chen (NIBIB/NIH), Mingnan Chen (University of Utah)
Special Issue Progress in Gene Editing Nanotheranostics. Guest Editors: Gang Han (University of Massachusetts Medical School), Wen Xue (University of Massachusetts Medical School), Qiaobing Xu (Tufts University)
Special Issue The EPR effect and beyond: Strategies to improve tumor targeting and nanomedicine efficacy. Guest Editors: Yang Shi (RWTH Aachen University), Roy van der Meel (Eindhoven University of Technology), Twan Lammers (RWTH Aachen University), Xiaoyuan (Shawn) Chen (NIBIB/NIH)
Special Issue Progress in Supramolecular Nanotheranostics. Guest Editors: Xiaoyuan (Shawn) Chen (NIBIB/NIH); Gang Zheng (University of Toronto); Jianjun Cheng (University of Illinois Urbana-Champaign); Yi-Yan Yang (Institute of Bioengineering and Nanotechnology, Singapore)

Congratulations to Dr. Chen for being elected as AIMBE fellow: http://aimbe.org/college-of-fellows/cof-2103/

Dr. Chen was recognized as Selected Highly Prolific Authors  (most published articles in the past 5 years) for 3 ACS journals (ACS Nano, Bioconjugate Chemistry, and Molecular Pharmaceutics). More details: http://journalstars.acs.org/

Dr. Chen received the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.

NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Published Special Issues