Research Paper ecPICK: A deep learning-enabled spatial diagnostic platform for direct ecDNA identification and clinical prognosis across pan-cancer histopathology Full text PDF
Review Stimuli-responsive nanomaterials for wound healing: advances and emerging directions Full text PDF
Research Paper Converting focused ultrasound–based boiling histotripsy into a systemic cancer vaccine using antigen-capturing microparticles Full text PDF
Research Paper BMAL1 regulates tubular epithelial-derived exosomal miR-27a-3p to inhibit macrophage–myofibroblast transition and alleviate ischemia/reperfusion-induced renal fibrosis Full text PDF
Research Paper First-in-human ex-vivo validation of carbonic anhydrase IX-PET for high-risk renal cancer (CAT-VHL - PNRR-POC-2023-12377493) Full text PDF
Review Integrating the hallmarks of cancer into autophagy: a perspective from underlying mechanisms to therapeutic strategies Full text PDF
Issue 10; 2026
Founding Editor-in-Chief:
Prof. Xiaoyuan (Shawn) Chen, PhD
Profile
Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.
Background: Tumors with an immunosuppressive tumor microenvironment (TME) limit effective anti-tumor immunity. Focused ultrasound–based boiling histotripsy (HT) is a noninvasive technique that mechanically ablates tumors while generating acellular lysates with preserved tumor antigens in situ. However, HT alone elicits insufficient anti-tumor immune activation to induce regression of both local and metastatic tumors, particularly in immunoresistant ...