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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.


Editorial
Emerging evidence of myocardial injury in COVID-19: A path through the smoke
Gregorio Tersalvi, Giacomo Veronese, Dario Winterton
Theranostics 2020; 10(21): 9888-9889. doi:10.7150/thno.50788
[Abstract] [Full text] [PDF]


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Research Paper
Targeted Manganese doped silica nano GSH-cleaner for treatment of Liver Cancer by destroying the intracellular redox homeostasis
Hongxia Tang, Chaoqun Li, Yue Zhang, Hongyue Zheng, Ying Cheng, Jingjing Zhu, Xiaojie Chen, Zhihong Zhu, Ji-Gang Piao, Fanzhu Li
Theranostics 2020; 10(21): 9865-9887. doi:10.7150/thno.46771
[Abstract] [Full text] [PDF]


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Review
Exquisite design of injectable Hydrogels in Cartilage Repair
Jiawei Wu, Qi Chen, Chao Deng, Baoping Xu, Zeiyan Zhang, Yang Yang, Tingli Lu
Theranostics 2020; 10(21): 9843-9864. doi:10.7150/thno.46450
[Abstract] [Full text] [PDF]


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Research Paper
O-GlcNAcylation of SIX1 enhances its stability and promotes Hepatocellular Carcinoma Proliferation
Yi Chu, Mingzuo Jiang, Nan Wu, Bing Xu, Wenjiao Li, Haiming Liu, Song Su, Yanting Shi, Hao Liu, Xiaoliang Gao, Xin Fu, Di Chen, Xiaowei Li, Weijie Wang, Jie Liang, Yongzhan Nie, Daiming Fan
Theranostics 2020; 10(21): 9830-9842. doi:10.7150/thno.45161
[Abstract] [Full text] [PDF]


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Research Paper
Efficacy-shaping nanomedicine by loading Calcium Peroxide into Tumor Microenvironment-responsive Nanoparticles for the Antitumor Therapy of Prostate Cancer
Di Wu, Zi-Qiang Zhu, Hai-Xiao Tang, Zhi-En Shi, Jian Kang, Qiang Liu, Jun Qi
Theranostics 2020; 10(21): 9808-9829. doi:10.7150/thno.43631
[Abstract] [Full text] [PDF]


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Research Paper
Low-intensity Pulsed Ultrasound regulates alveolar bone homeostasis in experimental Periodontitis by diminishing Oxidative Stress
Siqi Ying, Minmin Tan, Ge Feng, Yunchun Kuang, Duanjing Chen, Jie Li, Jinlin Song
Theranostics 2020; 10(21): 9789-9807. doi:10.7150/thno.42508
[Abstract] [Full text] [PDF]


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Research Paper
Prediction of clinically relevant Pancreatico-enteric Anastomotic Fistulas after Pancreatoduodenectomy using deep learning of Preoperative Computed Tomography
Wei Mu, Chang Liu, Feng Gao, Yafei Qi, Hong Lu, Zaiyi Liu, Xianyi Zhang, Xiaoli Cai, Ruo Yun Ji, Yang Hou, Jie Tian, Yu Shi
Theranostics 2020; 10(21): 9779-9788. doi:10.7150/thno.49671
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Research Paper
Plasma protein-based signature predicts distant metastasis and induction chemotherapy benefit in Nasopharyngeal Carcinoma
Yelin Liang, Junyan Li, Qian Li, Linglong Tang, Lei Chen, Yanping Mao, Qingmei He, Xiaojing Yang, Yuan Lei, Xiaohong Hong, Yin Zhao, Shiwei He, Ying Guo, Yaqin Wang, Panpan Zhang, Na Liu, Yingqin Li, Jun Ma
Theranostics 2020; 10(21): 9767-9778. doi:10.7150/thno.47882
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Review
P21-Activated Kinase 1: Emerging biological functions and potential therapeutic targets in Cancer
Dahong Yao, Chenyang Li, Muhammad Shahid Riaz Rajoka, Zhendan He, Jian Huang, Jinhui Wang, Jin Zhang
Theranostics 2020; 10(21): 9741-9766. doi:10.7150/thno.46913
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Research Paper
HI-511 overcomes melanoma drug resistance via targeting AURKB and BRAF V600E
Xiaoyu Chang, Tianshun Zhang, Qiushi Wang, Moeez Ghani Rathore, Kanamata Reddy, Hanyong Chen, Seung Ho Shin, Wei-ya Ma, Ann M Bode, Zigang Dong
Theranostics 2020; 10(21): 9721-9740. doi:10.7150/thno.44342
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Research Paper
Fibrinogen-like protein 2 aggravates nonalcoholic steatohepatitis via interaction with TLR4, eliciting inflammation in macrophages and inducing hepatic lipid metabolism disorder
Junjian Hu, Hongwu Wang, Xitang Li, Yonggang Liu, Yuqiang Mi, Hongyan Kong, Dong Xi, Weiming Yan, Xiaoping Luo, Qin Ning, Xiaojing Wang
Theranostics 2020; 10(21): 9702-9720. doi:10.7150/thno.44297
[Abstract] [Full text] [PDF]


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Research Paper
Retinoic acid promotes metabolic maturation of human Embryonic Stem Cell-derived Cardiomyocytes
Shumei Miao, Dandan Zhao, Xiaoxiao Wang, Xuan Ni, Xing Fang, Miao Yu, Lingqun Ye, Jingsi Yang, Hongchun Wu, Xinglong Han, Lina Qu, Lei Li, Feng Lan, Zhenya Shen, Wei Lei, Zhen-Ao Zhao, Shijun Hu
Theranostics 2020; 10(21): 9686-9701. doi:10.7150/thno.44146
[Abstract] [Full text] [PDF]


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Research Paper
GSK-3β activation accelerates early-stage consumption of Hippocampal Neurogenesis in senescent mice
Fei Liu, Na Tian, Hua-Qiu Zhang, Shi-Hong Li, Qiu-Zhi Zhou, Ying Yang, Jie Zheng, Jian-Zhi Wang
Theranostics 2020; 10(21): 9674-9685. doi:10.7150/thno.43829
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Research Paper
Myocardial injury and COVID-19: Serum hs-cTnI level in risk stratification and the prediction of 30-day fatality in COVID-19 patients with no prior cardiovascular disease
Jiatian Cao, Yan Zheng, Zhe Luo, Zhendong Mei, Yumeng Yao, Zilong Liu, Chao Liang, Hongbo Yang, Yanan Song, Kaihuan Yu, Yan Gao, Chouwen Zhu, Zheyong Huang, Juying Qian, Junbo Ge
Theranostics 2020; 10(21): 9663-9673. doi:10.7150/thno.47980
[Abstract] [Full text] [PDF]


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Research Paper
HDAC3 inhibition ameliorates ischemia/reperfusion-induced brain injury by regulating the microglial cGAS-STING pathway
Yajin Liao, Jinbo Cheng, Xiangxi Kong, Shuoshuo Li, Xiaoheng Li, Meijuan Zhang, He Zhang, Tianli Yang, Yuan Dong, Jun Li, Yun Xu, Zengqiang Yuan
Theranostics 2020; 10(21): 9644-9662. doi:10.7150/thno.47651
[Abstract] [Full text] [PDF]


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Research Paper
LncRNA-SLC16A1-AS1 induces metabolic reprogramming during Bladder Cancer progression as target and co-activator of E2F1
Stella Logotheti, Stephan Marquardt, Shailendra K. Gupta, Christin Richter, Berdien A.H. Edelhäuser, David Engelmann, Julia Brenmoehl, Christoph Söhnchen, Nico Murr, Michael Alpers, Krishna P. Singh, Olaf Wolkenhauer, Dirk Heckl, Alf Spitschak, Brigitte M. Pützer
Theranostics 2020; 10(21): 9620-9643. doi:10.7150/thno.44176
[Abstract] [Full text] [PDF]

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD
Editor-in-chief profile

new Latest Impact Factor 8.579

Nanotheranostics is indexed in MEDLINE and PubMed Central ...

Research Paper
Histologic evaluation of activation of acute inflammatory response in a mouse model following ultrasound-mediated blood-brain barrier using different acoustic pressures and microbubble doses
Aurea Pascal, Ningrui Li, Kendra J. Lechtenberg, Jarrett Rosenberg, Raag D. Airan, Michelle L. James, Donna M. Bouley, Kim Butts Pauly
Nanotheranostics 2020; 4(4): 210-223. doi:10.7150/ntno.49898
[Abstract] [Full text] [PDF]


Research Paper
A Gold Nanoparticle Bouquet held on plasma membrane: An ultrasensitive dark-field imaging approach for Cancer Cell Analysis
Yue Cao, Jie Wang, Qiao-Yan Jiang, Li Hu, You-Jia Yu, Yan-Fang Yu, Feng Chen
Nanotheranostics 2020; 4(4): 201-209. doi:10.7150/ntno.41639
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Research Paper
Brain iron deposition after Ferumoxytol-enhanced MRI: A study of Porcine Brains
Ashok Joseph Theruvath, Maryam Aghighi, Michael Iv, Hossein Nejadnik, Jonathan Lavezo, Laura Jean Pisani, Heike Elisabeth Daldrup-Link
Nanotheranostics 2020; 4(4): 195-200. doi:10.7150/ntno.46356
[Abstract] [Full text] [PDF] [PubMed] [PMC]

CFP - Special Issue: Extracellular vesicles in pathogenesis, diagnosis, or therapeutics of human diseases. Guest Editor: Ming-Lin Liu, Perelman School of Medicine, University of Pennsylvania.
Special Issue: Noble-metal Nanostructures for Theranostics. Guest Editors: Xiaohu Xia, University of Central Florida and Hui Wei, Nanjing University
Special Issue Targeting the Cancer Stem Cells. Guest Editor: Fei Chen, PhD, Professor, Wayne State University
Special Issue Progress in Gene Editing Nanotheranostics. Guest Editors: Gang Han (University of Massachusetts Medical School), Wen Xue (University of Massachusetts Medical School), Qiaobing Xu (Tufts University)
Special Issue Progress in Supramolecular Nanotheranostics. Guest Editors: Xiaoyuan (Shawn) Chen (NIBIB/NIH); Gang Zheng (University of Toronto); Jianjun Cheng (University of Illinois Urbana-Champaign); Yi-Yan Yang (Institute of Bioengineering and Nanotechnology, Singapore)

Congratulations to Dr. Chen for being elected as AIMBE fellow: http://aimbe.org/college-of-fellows/cof-2103/

Dr. Chen was recognized as Selected Highly Prolific Authors  (most published articles in the past 5 years) for 3 ACS journals (ACS Nano, Bioconjugate Chemistry, and Molecular Pharmaceutics). More details: http://journalstars.acs.org/

Dr. Chen received the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.

NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Published Special Issues