ISSN: 1838-7640Theranostics
Global reach, higher impact
Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.
Review
Advances in subpopulation separation and detection of extracellular vesicles: for liquid biopsy and downstream research
Zi-Xiu Liu, Gang Chen, Zi-Li Yu
Theranostics 2025; 15(3): 1135-1155. doi:10.7150/thno.106459
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Research Paper
Drug repositioning of mesalamine via supramolecular nanoassembly for the treatment of drug-induced acute liver failure
Byeongmin Park, Eun Hye Kim, Hochung Jang, Yelee Kim, Youngri Ryu, Jiwoong Choi, Dongwon Shin, Myung Chul Lee, Yoosoo Yang, Kwangmeyung Kim, Sangmin Lee, Sun Hwa Kim, Man Kyu Shim
Theranostics 2025; 15(3): 1122-1134. doi:10.7150/thno.101358
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Research Paper
Non-invasive volumetric ultrasound localization microscopy detects vascular changes in mice with Alzheimer's disease
Rebecca M. Jones, Ryan M. DeRuiter, Mohanish Deshmukh, Paul A. Dayton, Gianmarco F. Pinton
Theranostics 2025; 15(3): 1110-1121. doi:10.7150/thno.99097
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Research Paper
A specific and adaptable approach to track CD206+ macrophages by molecular MRI and fluorescence imaging
Cuihua Wang, Negin Jalali Motlagh, Gregory R. Wojtkiewicz, Hongzhi Yang, Hyung-Hwan Kim, John W. Chen
Theranostics 2025; 15(3): 1094-1109. doi:10.7150/thno.96488
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Research Paper
Perfluorocarbon-polyepinephrine core-shell nanoparticles as a near-infrared light activatable theranostic platform for bimodal imaging-guided photothermal/chemodynamic synergistic cancer therapy
Kyung Kwan Lee, Kyung-Woo Park, Sang Cheon Lee, Chang-Soo Lee
Theranostics 2025; 15(3): 1077-1093. doi:10.7150/thno.102743
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Research Paper
Bisphosphonate-mineralized nano-IFNγ suppresses residual tumor growth caused by incomplete radiofrequency ablation through metabolically remodeling tumor-associated macrophages
Zhicheng Yan, Bing Wang, Yuhan Shen, Junji Ren, Meifang Chen, Yunhui Jiang, Hao Wu, Wenbing Dai, Hua Zhang, Xueqing Wang, Qiang Zhang, Wei Yang, Bing He
Theranostics 2025; 15(3): 1057-1076. doi:10.7150/thno.100998
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Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD
Editor-in-chief profile
Congratulations! Professor Chen has been elected as a member of the Academia Europaea.
- Theranostics is indexed by Science Citation Index (SCI) and MEDLINE. (Full index information)
- Full texts of articles in PubMed Central and Europe PMC. Abstracts in PubMed.
Alzheimer's Disease (AD) is the most common form of dementia and one of the leading causes of death. AD is known to be correlated to tortuosity in the microvasculature as well as decreases in blood flow throughout the brain. However, the mechanisms behind these changes and their causal relation to AD are poorly understood. Methods: Here, we use volumetric ultrasound localization microscopy (ULM) to non-invasively and quantitatively compare the microvascular morphology and flow dynamics of five wildtype (WT) and five APPNL-G-F Knock-in mice, a mouse model of AD, across a 1cmx1cmx1cm brain volume....
Rationale: The mannose receptor (CD206, expressed by the gene Mrc1) is a surface marker overexpressed by anti-inflammatory and pro-tumoral macrophages. As such, CD206+ macrophages play key roles in the immune response to different pathophysiological conditions and represent a promising diagnostic and therapeutic target. However, methods to specifically target these cells remain challenging. In this study, we describe a multi-mannose approach to develop CD206-targeting fluorescent and MRI agents that specifically and sensitively detect and monitor CD206+ macrophage immune response in different disease....
Nanotheranostics is indexed in MEDLINE and PubMed Central ...
Research Paper
Therapeutic Potential of Feline Adipose-Derived Stem Cell Exosomes in the Treatment of Feline Idiopathic Cystitis: A Characterization and Functional Analysis of miRNA Content
Andrea Rubini, Federica Zanotti, Danilo Licastro, Giulia Calogero, Gisella Bettini, Cristiana Piccoli, Giuseppe Rubini, Luca Lovatti, Barbara Zavan
Nanotheranostics 2025; 9(1): 38-51.
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