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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.

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Review
Harnessing glucose metabolism with nanomedicine for cancer treatment
Xudong Wang, Liping Wang, Qingyi Hao, Meng Cai, Xueting Wang, Wenlin An
Theranostics 2024; 14(17): 6831-6882. doi:10.7150/thno.100036
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Research Paper
Real-time monitoring of single dendritic cell maturation using deep learning-assisted surface-enhanced Raman spectroscopy
Cai Zhang, Mengling Wang, Houde Wu, Hongmei Gao, Pengyun Wu, Li Guo, Dingbin Liu
Theranostics 2024; 14(17): 6818-6830. doi:10.7150/thno.100298
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Research Paper
DNASE1L3-mediated PANoptosis enhances the efficacy of combination therapy for advanced hepatocellular carcinoma
Jingchun Wang, Yu Chen, Yanquan Xu, Jiangang Zhang, Shuai Yang, Yu Zhou, Juan Lei, Ran Ren, Yang Chen, Huakan Zhao, Yongsheng Li, Shiming Yang
Theranostics 2024; 14(17): 6798-6817. doi:10.7150/thno.102995
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Research Paper
Low hepatic artery blood flow mediates NET extravasation through the regulation of PIEZO1/SRC signaling to induce biliary complications after liver transplantation
Hongqiang Yu, Yujun Zhang, Ling Shuai, Cong Peng, Changchun Zhao, Yan Jiang, Ling Yao, Jiejuan Lai, Zhiyu Chen, Leida Zhang, Xiang Xiong, Xiaojun Wang
Theranostics 2024; 14(17): 6783-6797. doi:10.7150/thno.99514
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Research Paper
Role of damaged mitochondrial transfer in alpha-particle generator 212Pb radiation-induced bystander effect
Mengdie Yang, Lusheng Wang, Shanshan Qin, Xiongxin Dai, Jianguo Li, Liwei An, Lijuan Song, Jie Gao, Zongtai Han, Fei Yu
Theranostics 2024; 14(17): 6768-6782. doi:10.7150/thno.101922
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Review
Targeting sirtuins for cancer therapy: epigenetics modifications and beyond
Hui Shen, Xinyi Qi, Yue Hu, Yi Wang, Jin Zhang, Zhongyu Liu, Zheng Qin
Theranostics 2024; 14(17): 6726-6767. doi:10.7150/thno.100667
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Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD
Editor-in-chief profile

Congratulations! Professor Chen has been elected as a member of the Academia Europaea.

Rationale: 212Pb, a promising in vivo alpha-particle generator of 212Bi, has aroused much interest as a therapeutic radionuclide. For the development of targeted alpha therapy (TAT), it is important to determine the contribution of targeted effects in irradiated cells, and also of non-targeted effects in non-irradiated bystander cells. Currently, the critical roles of mitochondrial transfer in cellular crosstalk have garnered significant attention. However, the specific involvement of damaged mitochondrial transfer in orchestrating this alpha-particle radiation-induced bystander effect (RIBE) needs....
Background: Dynamic real-time detection of dendritic cell (DC) maturation is pivotal for accurately predicting immune system activation, assessing vaccine efficacy, and determining the effectiveness of immunotherapy. The heterogeneity of cells underscores the significance of assessing the maturation status of each individual cell, while achieving real-time monitoring of DC maturation at the single-cell level poses significant challenges. Surface-enhanced Raman spectroscopy (SERS) holds great potential for providing specific fingerprinting information of DCs to detect biochemical alterations and....

Nanotheranostics is indexed in MEDLINE and PubMed Central ...

Research Paper
Unraveling In vivo Potential of Curcumin-loaded Graphene Quantum Dots on Drug Delivery and Release Kinetics Aspects of Cancer Treatment
Mochamad Z. Fahmi, Siti F. A. Sugito, Aswandi Wibrianto, Siska Novania, Shinta Widyastuti, Musbahu Adam Ahmad, Satya C. W. Sakti, Lee H. Voon
Nanotheranostics 2024; 8(4): 521-534.
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