Cover image

Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.


Graphic abstract

Review
Targeting ferroptosis-based cancer therapy using nanomaterials: strategies and applications
Lianxiang Luo, Han Wang, Wen Tian, Xiaoling Li, Zheng Zhu, Riming Huang, Hui Luo
Theranostics 2021; 11(20): 9937-9952. doi:10.7150/thno.65480
[Abstract] [Full text] [PDF]


Graphic abstract

Research Paper
CRTC3, a sensor and key regulator for melanogenesis, as a tunable therapeutic target for pigmentary disorders
Hanju Yoo, Ha-Ri Lee, Ki-Hyun Kim, Min-Ah Kim, Seunghyun Bang, Young-Ho Kang, Woo-hyung Kim, Youngsup Song, Sung Eun Chang
Theranostics 2021; 11(20): 9918-9936. doi:10.7150/thno.66378
[Abstract] [Full text] [PDF]


Graphic abstract

Research Paper
Clinically translatable gold nanozymes with broad spectrum antioxidant and anti-inflammatory activity for alleviating acute kidney injury
Dong-Yang Zhang, Tianhui Tu, Muhammad Rizwan Younis, Kathy S. Zhu, Hengke Liu, Shan Lei, Junle Qu, Jing Lin, Peng Huang
Theranostics 2021; 11(20): 9904-9917. doi:10.7150/thno.66518
[Abstract] [Full text] [PDF]


Graphic abstract

Research Paper
Establishment of tumor inflammasome clusters with distinct immunogenomic landscape aids immunotherapy
Qingyu Liang, Jianqi Wu, Xin Zhao, Shuai Shen, Chen Zhu, Tianqi Liu, Xiao Cui, Ling Chen, Chunmi Wei, Peng Cheng, Wen Cheng, Anhua Wu
Theranostics 2021; 11(20): 9884-9903. doi:10.7150/thno.63202
[Abstract] [Full text] [PDF]


Graphic abstract

Research Paper
Biological relevance of Granzymes A and K during E. coli sepsis
Iratxe Uranga-Murillo, Elena Tapia, Marcela Garzón-Tituaña, Ariel Ramirez-Labrada, Llipsy Santiago, Cecilia Pesini, Patricia Esteban, Francisco J Roig, Eva M Galvez, Phillip I Bird, Julián Pardo, Maykel Arias
Theranostics 2021; 11(20): 9873-9883. doi:10.7150/thno.59418
[Abstract] [Full text] [PDF]


Graphic abstract

Research Paper
Estimating dynamic vascular perfusion based on Er-based lanthanide nanoprobes with enhanced down-conversion emission beyond 1500 nm
Qian Jia, Zheng Li, Mingli Bai, Haohao Yan, Ruili Zhang, Yu Ji, Yanbin Feng, Zuo Yang, Zhongliang Wang, Jianxiong Li
Theranostics 2021; 11(20): 9859-9872. doi:10.7150/thno.65771
[Abstract] [Full text] [PDF]


Graphic abstract

Research Paper
Multiple regression analysis of a comprehensive transcriptomic data assembly elucidates mechanically- and biochemically-driven responses to focused ultrasound blood-brain barrier disruption
Alexander S. Mathew, Catherine M. Gorick, Richard J. Price
Theranostics 2021; 11(20): 9847-9858. doi:10.7150/thno.65064
[Abstract] [Full text] [PDF]


Graphic abstract

Research Paper
A programmable hierarchical-responsive nanoCRISPR elicits robust activation of endogenous target to treat cancer
Chao Liu, Ning Wang, Rui Luo, Lu Li, Wen Yang, Xiye Wang, Meiling Shen, Qinjie Wu, Changyang Gong
Theranostics 2021; 11(20): 9833-9846. doi:10.7150/thno.62449
[Abstract] [Full text] [PDF]


Graphic abstract

Research Paper
CST6 protein and peptides inhibit breast cancer bone metastasis by suppressing CTSB activity and osteoclastogenesis
Xiaoxun Li, Yajun Liang, Cheng Lian, Fangli Peng, Yansen Xiao, Yunfei He, Chengxin Ma, Yuan Wang, Peiyuan Zhang, Yuhan Deng, Yunpeng Su, Cheng Luo, Xiangyin Kong, Qingcheng Yang, Tong Liu, Guohong Hu
Theranostics 2021; 11(20): 9821-9832. doi:10.7150/thno.62187
[Abstract] [Full text] [PDF]


Graphic abstract

Research Paper
Interleukin-4 and interleukin-13 induce different metabolic profiles in microglia and macrophages that relate with divergent outcomes after spinal cord injury
Jesus Amo-Aparicio, Joana Garcia-Garcia, Isaac Francos-Quijorna, Andrea Urpi, Anna Esteve-Codina, Marta Gut, Albert Quintana, Ruben Lopez-Vales
Theranostics 2021; 11(20): 9805-9820. doi:10.7150/thno.65203
[Abstract] [Full text] [PDF]


Graphic abstract

Research Paper
CLEC-2-dependent platelet subendothelial accumulation by flow disturbance contributes to atherogenesis in mice
Chaojun Tang, Lei Wang, Yulan Sheng, Zhong Zheng, Zhanli Xie, Fan Wu, Tao You, Lijie Ren, Lijun Xia, Changgeng Ruan, Li Zhu
Theranostics 2021; 11(20): 9791-9804. doi:10.7150/thno.64601
[Abstract] [Full text] [PDF]


Graphic abstract

Research Paper
Identification of three tumor antigens and immune subtypes for mRNA vaccine development in diffuse glioma
Quanwei Zhou, Xuejun Yan, Hecheng Zhu, Zhaoqi Xin, Jin Zhao, Wenyue Shen, Wen Yin, Youwei Guo, Hongjuan Xu, Ming Zhao, Weidong Liu, Xingjun Jiang, Caiping Ren
Theranostics 2021; 11(20): 9775-9790. doi:10.7150/thno.61677
[Abstract] [Full text] [PDF]


Erratum
Inhibition of miR-331-3p and miR-9-5p ameliorates Alzheimer's disease by enhancing autophagy: Erratum
Meng-Lu Chen, Chun-Gu Hong, Tao Yue, Hong-Ming Li, Ran Duan, Wen-Bao Hu, Jia Cao, Zhen-Xing Wang, Chun-Yuan Chen, Xiong-Ke Hu, Ben Wu, Hao-Ming Liu, Yi-Juan Tan, Jiang-Hua Liu, Zhong-Wei Luo, Yan Zhang, Shan-Shan Rao, Ming-Jie Luo, Hao Yin, Yi-Yi Wang, Kun Xia, Si-Yuan Tang, Hui Xie, Zheng-Zhao Liu
Theranostics 2021; 11(20): 9774. doi:10.7150/thno.67227
[Abstract] [Full text] [PDF]


Erratum
Nanosonosensitizers for Highly Efficient Sonodynamic Cancer Theranostics: Erratum
Ju Huang, Fengqiu Liu, Xiaoxia Han, Liang Zhang, Zhongqian Hu, Qinqin Jiang, Zhigang Wang, Haitao Ran, Dong Wang, Pan Li
Theranostics 2021; 11(20): 9772-9773. doi:10.7150/thno.67168
[Abstract] [Full text] [PDF]


Graphic abstract

Research Paper
USP32 confers cancer cell resistance to YM155 via promoting ER-associated degradation of solute carrier protein SLC35F2
Arun Pandian Chandrasekaran, Kamini Kaushal, Chang-Hwan Park, Kye-Seong Kim, Suresh Ramakrishna
Theranostics 2021; 11(20): 9752-9771. doi:10.7150/thno.63806
[Abstract] [Full text] [PDF]


Graphic abstract

Research Paper
Osteoblast-derived EGFL6 couples angiogenesis to osteogenesis during bone repair
Kai Chen, Shijie Liao, Yicheng Li, Haibo Jiang, Yun Liu, Chao Wang, Vincent Kuek, Jacob Kenny, Boxiang Li, Qian Huang, Jianxin Hong, Yan Huang, Shek Man Chim, Jennifer Tickner, Nathan J. Pavlos, Jinmin Zhao, Qian Liu, An Qin, Jiake Xu
Theranostics 2021; 11(20): 9738-9751. doi:10.7150/thno.60902
[Abstract] [Full text] [PDF]

More ...

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD
Editor-in-chief profile

new Latest Impact Factor 11.556.

Nanotheranostics is indexed in MEDLINE and PubMed Central ...

Research Paper
Flavin Adenine Dinucleotide (FAD) Pegylated (PEG)-Complexes: Proof of Concept (PoC) of theranostic tool on a Murine Breast Cancer Model
Celia Arib, Hui Liu, Qiqian Liu, Anne-Marie Cieutat, Didier Paleni, Xiaowu Li, Jolanda Spadavecchia
Nanotheranostics 2022; 6(2): 175-183. doi:10.7150/ntno.63496
[Abstract] [Full text] [PDF]


Research Paper
Development of CD44E/s dual-targeting DNA aptamer as nanoprobe to deliver treatment in hepatocellular carcinoma
Cario Wing-Sze Lo, Cecilia Ka Wing Chan, Jianqing Yu, Mian He, Chung Hang Jonathan Choi, James Yun Wong Lau, Nathalie Wong
Nanotheranostics 2022; 6(2): 161-174. doi:10.7150/ntno.62639
[Abstract] [Full text] [PDF]


Research Paper
Metal-Organic Frameworks for Bioimaging: Strategies and Challenges
Yanfei Liu, Ting Jiang, Zhenbao Liu
Nanotheranostics 2022; 6(2): 143-160. doi:10.7150/ntno.63458
[Abstract] [Full text] [PDF]

Special Issue: Osteoarthritis Theranostics. Guest Editors: Dr. WEN, CHUNYI, Dr. Magali Cucchiarini.
Special Issue: Extracellular vesicles in pathogenesis, diagnosis, or therapeutics of human diseases. Guest Editor: Ming-Lin Liu, Perelman School of Medicine, University of Pennsylvania.
Special Issue: Noble-metal Nanostructures for Theranostics. Guest Editors: Xiaohu Xia, University of Central Florida and Hui Wei, Nanjing University
Special Issue Targeting the Cancer Stem Cells. Guest Editor: Fei Chen, PhD, Professor, Wayne State University
Special Issue Progress in Gene Editing Nanotheranostics. Guest Editors: Gang Han (University of Massachusetts Medical School), Wen Xue (University of Massachusetts Medical School), Qiaobing Xu (Tufts University)
Special Issue Progress in Supramolecular Nanotheranostics. Guest Editors: Xiaoyuan (Shawn) Chen (NIBIB/NIH); Gang Zheng (University of Toronto); Jianjun Cheng (University of Illinois Urbana-Champaign); Yi-Yan Yang (Institute of Bioengineering and Nanotechnology, Singapore)

Congratulations to Dr. Chen for being elected as AIMBE fellow: https://aimbe.org/college-of-fellows/cof-2103/

Dr. Chen was recognized as Selected Highly Prolific Authors  (most published articles in the past 5 years) for 3 ACS journals (ACS Nano, Bioconjugate Chemistry, and Molecular Pharmaceutics). More details: http://journalstars.acs.org/

Dr. Chen received the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.

NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Published Special Issues