Theranostics

Research Paper Piezocatalytic microneedle platform for biocompatible and antibacterial ROS therapy of infected wounds Zesheng Chen, Fanghan Li, Wenwen Cheng, Ye Yang, Zhengyao Zhang, Wang Wang, Weikang Hu, Weijun Liu, Zijian Wang Theranostics 2027; 17(1): 627-645. doi:10.7150/thno.142353 Full text PDF

Research Paper Z-Scheme interface engineering in bimetallic sulfide sonozymes to dismantle tumor antioxidant defenses for ferroptosis-driven sono-immunotherapy Yang Yang, Xiuwei Wu, Zhenlin Zhang, Dengyu Pan, Bijiang Geng, Yunsheng Cheng Theranostics 2027; 17(1): 604-626. doi:10.7150/thno.140120 Full text PDF

Research Paper Bidirectional ROS cascade amplification in a TME-activatable nanoplatform for MRI-guided sono-chemodynamic cancer therapy Linrong Shi, Chenhui He, Zhezhu Nan, Yang Liu, Jiayue Li, Mingxi Wan, Ping Li, Yi Feng Theranostics 2027; 17(1): 589-603. doi:10.7150/thno.139788 Full text PDF

Research Paper Targeted delivery of selenomethionine by RGD-functionalized liposomes inhibits AAD progression through dual modulation of inflammation and BRD4 lactylation Jiamin Xu, Xi Tan, Ke Hu, Xu Zhou, Xiaohan Fan, Lihua Tian, Heng Wu, Zhongnan Xia, Ya Wang, Xuemei Zhang, Changzhao Liu, Hongbo Chen, Lixing Wu, Yuhua Lei, Jing Zhang, Jiaxin Hu Theranostics 2027; 17(1): 573-588. doi:10.7150/thno.139857 Full text PDF

Research Paper Continuous generation of functional human iPSC-derived NK cells in a scalable hematopoietic organoid system Fawaz Saleh, Lucas Rebuffet, Roland Jacobs, Agnes Bonifacius, Berislav Čuvalo, Edwin Emilio Valdivia Malqui, Adrien Mazuel, Reinhold Förster, Britta Eiz-Vesper, Greta Meyer, Svenja Gaedcke, Sabine Buyny, Dominik Schmiedel, Duck Cho, Marco Carvalho Oliveira, Christine Falk, Adan C. Jirmo, Gesine Hansen, Eric Vivier, Nico Lachmann Theranostics 2027; 17(1): 551-572. doi:10.7150/thno.135792 Full text PDF

Research Paper Therapeutic decoupling of restenosis prevention from impaired vascular healing with regenerative nanovesicle-eluting bioresorbable scaffolds Min-Kyu Kang, Ji Won Kim, Yu-Jeong Lee, Dong-Sung Won, Gi Wook Lee, Weiqiang Liu, Chae-lin Kim, Su-Hyun Park, Ju-El Kim, Tae-Hyun Heo, Seung Jin Eo, Gun-Jae Jeong, Ilkoo Noh, Min-Ho Kang, Han Young Kim, Young Min Shin, Jung Bok Lee, Minseo Park, Hyun-Ji Park, Rosaire Mongrain, Hyung Il Kim, Jung-Hoon Park, Jeong-Kee Yoon Theranostics 2027; 17(1): 524-550. doi:10.7150/thno.138957 Full text PDF

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Issue 14; 2026

Founding Editor-in-Chief:
Prof. Xiaoyuan (Shawn) Chen, PhD
Profile

Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.

Theranostics is indexed by Science Citation Index (SCI) and MEDLINE. (Full index information)
Full texts of articles in PubMed Central and Europe PMC. Abstracts in PubMed.
(For NIH-funded researchers) Save time by submitting your paper to us - this journal is in full compliance with NIH Public Access Requirement.

Special Issue - Advanced Cell and Gene Therapy Strategies for Precision Treatment of Autoimmune Diseases. Theme issue editors: Weisheng Guo (Guangzhou Medical University), Xiaoyuan Chen (Shandong Cancer Hospital and Institute).

Continuous generation of functional human iPSC-derived NK cells in a scalable hematopoietic organoid system

Rationale: Induced pluripotent stem cell (iPSC)-derived natural killer (iNK) cells offer an off-the-shelf platform for cancer immunotherapy, but scalable production and consistent functionality remain key challenges. Deeper analytical and bioprocess insights into scalable manufacturing is needed to improve the quality, consistency, and affordability of cell products. Here we aimed to develop and characterize a scalable bioprocess for the continuous ...