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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.


Erratum
Microporous polysaccharide multilayer coated BCP composite scaffolds with immobilised calcitriol promote osteoporotic bone regeneration both in vitro and in vivo: Erratum
Qian Tang, Zhichao Hu, Haiming Jin, Gang Zheng, XingFang Yu, Gang Wu, Haixiao Liu, Zhenzhong Zhu, Huazi Xu, Changqing Zhang, Liyan Shen
Theranostics 2021; 11(13): 6524-6525. doi:10.7150/thno.61641
[Abstract] [Full text] [PDF]


Erratum
Acidic Microenvironment Up-Regulates Exosomal miR-21 and miR-10b in Early-Stage Hepatocellular Carcinoma to Promote Cancer Cell Proliferation and Metastasis: Erratum
Xiao-Peng Tian, Chen-Yuan Wang, Xiao-Han Jin, Mei Li, Feng-Wei Wang, Wei-Juan Huang, Jing-Ping Yun, Rui-Hua Xu, Qing-Qing Cai, Dan Xie
Theranostics 2021; 11(13): 6522-6523. doi:10.7150/thno.60140
[Abstract] [Full text] [PDF]


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Research Paper
Targeted delivery of neural progenitor cell-derived extracellular vesicles for anti-inflammation after cerebral ischemia
Tian Tian, Lei Cao, Chuan He, Qing Ye, Ruyu Liang, Weiyan You, Huixin Zhang, Jiahuan Wu, Jinhai Ye, Bakhos A. Tannous, Jun Gao
Theranostics 2021; 11(13): 6507-6521. doi:10.7150/thno.56367
[Abstract] [Full text] [PDF]


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Research Paper
Apilimod alters TGFβ signaling pathway and prevents cardiac fibrotic remodeling
Mathieu Cinato, Laurie Guitou, Amira Saidi, Andrei Timotin, Erwan Sperazza, Thibaut Duparc, Sergey N. Zolov, Sai Srinivas Panapakkam Giridharan, Lois S. Weisman, Laurent O. Martinez, Jerome Roncalli, Oksana Kunduzova, Helene Tronchere, Frederic Boal
Theranostics 2021; 11(13): 6491-6506. doi:10.7150/thno.55821
[Abstract] [Full text] [PDF]


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Research Paper
Intelligent phototriggered nanoparticles induce a domino effect for multimodal tumor therapy
Xiao Xu, Chao Han, Can Zhang, Dan Yan, Chunling Ren, Lingyi Kong
Theranostics 2021; 11(13): 6477-6490. doi:10.7150/thno.55708
[Abstract] [Full text] [PDF]


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Research Paper
Single-cell transcriptome profiling reveals vascular endothelial cell heterogeneity in human skin
Qingyang Li, Zhenlai Zhu, Lei Wang, Yiting Lin, Hui Fang, Jie Lei, Tianyu Cao, Gang Wang, Erle Dang
Theranostics 2021; 11(13): 6461-6476. doi:10.7150/thno.54917
[Abstract] [Full text] [PDF]


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Research Paper
Phosphatidylserine-exposing tumor-derived microparticles exacerbate coagulation and cancer cell transendothelial migration in triple-negative breast cancer
Cong Zhang, Zhuowen Yang, Peng Zhou, Muxin Yu, Baorong Li, Yingmiao Liu, Jiaqi Jin, Wenhui Liu, Haijiao Jing, Jingwen Du, Jie Tian, Zhiyu Zhao, Jianxin wang, Yinzhu Chu, ChunMei Zhang, Valerie A Novakovic, Jialan Shi, Changjun Wu
Theranostics 2021; 11(13): 6445-6460. doi:10.7150/thno.53637
[Abstract] [Full text] [PDF]


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Research Paper
Neoantigen landscape in metastatic nasopharyngeal carcinoma
Mei Lin, Xiao-Long Zhang, Rui You, Qi Yang, Xiong Zou, Kai Yu, You-Ping Liu, Ru-Hai Zou, Yi-Jun Hua, Pei-Yu Huang, Jin Wang, Qi Zhao, Xiao-Bing Jiang, Jun Tang, Yang-Kui Gu, Tao Yu, Gui-Ping He, Yu-Long Xie, Zhi-Qiang Wang, Ting Liu, Si-Yuan Chen, Zhi-Xiang Zuo, Ming-Yuan Chen
Theranostics 2021; 11(13): 6427-6444. doi:10.7150/thno.53229
[Abstract] [Full text] [PDF]


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Review
Metal-phenolic networks: facile assembled complexes for cancer theranostics
Wensheng Xie, Zhenhu Guo, Lingyun Zhao, Yen Wei
Theranostics 2021; 11(13): 6407-6426. doi:10.7150/thno.58711
[Abstract] [Full text] [PDF]


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Research Paper
Human endoglin-CD3 bispecific T cell engager antibody induces anti-tumor effect in vivo
Liping Zhong, Wei Shi, Lu Gan, Xiuli Liu, Yu Huo, Pan Wu, Zhikun Zhang, Tao Wu, Hongmei Peng, Yong Huang, Yongxiang Zhao, Yulin Yuan, Zhiming Deng, Hongliang Tang
Theranostics 2021; 11(13): 6393-6406. doi:10.7150/thno.53121
[Abstract] [Full text] [PDF]


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Review
Recent progress in nanomedicine for enhanced cancer chemotherapy
Guoqing Wei, Yu Wang, Guang Yang, Yi Wang, Rong Ju
Theranostics 2021; 11(13): 6370-6392. doi:10.7150/thno.57828
[Abstract] [Full text] [PDF]


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Research Paper
DEPTOR stabilizes ErbB2 to promote the proliferation and survival of ErbB2-positive breast cancer cells
Yanli Bi, Xiaoyu Chen, Bajin Wei, Linchen Wang, Longyuan Gong, Haomin Li, Xiufang Xiong, Yongchao Zhao
Theranostics 2021; 11(13): 6355-6369. doi:10.7150/thno.51286
[Abstract] [Full text] [PDF]


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Review
Multifunctional nanoplatforms co-delivering combinatorial dual-drug for eliminating cancer multidrug resistance
Xiao Wei, Mingzhu Song, Weijie Li, Jing Huang, Guang Yang, Yi Wang
Theranostics 2021; 11(13): 6334-6354. doi:10.7150/thno.59342
[Abstract] [Full text] [PDF]


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Research Paper
CircUbe3a from M2 macrophage-derived small extracellular vesicles mediates myocardial fibrosis after acute myocardial infarction
Yan Wang, Chaofu Li, Ranzun Zhao, Zhimei Qiu, Changyin Shen, Zhenglong Wang, Weiwei Liu, Wei Zhang, Junbo Ge, Bei Shi
Theranostics 2021; 11(13): 6315-6333. doi:10.7150/thno.52843
[Abstract] [Full text] [PDF]


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Review
Perspectives on metals-based radioimmunotherapy (RIT): moving forward
Jordan M. White, Freddy E. Escorcia, Nerissa T. Viola
Theranostics 2021; 11(13): 6293-6314. doi:10.7150/thno.57177
[Abstract] [Full text] [PDF]


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Research Paper
KAT6A, a novel regulator of β-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1
Wenxue Liu, Zhiyan Zhan, Meiying Zhang, Bowen Sun, Qiqi Shi, Fei Luo, Mingda Zhang, Weiwei Zhang, Yanli Hou, Xiuying Xiao, Yanxin Li, Haizhong Feng
Theranostics 2021; 11(13): 6278-6292. doi:10.7150/thno.57455
[Abstract] [Full text] [PDF]

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD
Editor-in-chief profile

new Latest Impact Factor 8.579

Nanotheranostics is indexed in MEDLINE and PubMed Central ...

Research Paper
A Pegylated Flavin Adenine Dinucleotide PEG Complex to Boost Immunogenic and Therapeutic Effects in a Liver Cancer Model
Celia Arib, Hui Liu, Qiqian Liu, Anne-Marie Cieutat, Didier Paleni, Xiaowu Li, Jolanda Spadavecchia
Nanotheranostics 2021; 5(4): 405-416. doi:10.7150/ntno.59290
[Abstract] [Full text] [PDF]


Research Paper
Therapeutic Efficacy of Lactonic Sophorolipids: Nanoceria-Assisted Combination Therapy of NSCLC using HDAC and Hsp90 Inhibitors
Shuguftha Naz, Tuhina Banerjee, Filbert Totsingan, Kalee Woody, Richard A. Gross, Santimukul Santra
Nanotheranostics 2021; 5(4): 391-404. doi:10.7150/ntno.57675
[Abstract] [Full text] [PDF]


Research Paper
Engineering Extracellular Vesicles to Target Pancreatic Tissue In Vivo
Hiroaki Komuro, Yuki Kawai-Harada, Shakhlo Aminova, Nathaniel Pascual, Anshu Malik, Christopher H. Contag, Masako Harada
Nanotheranostics 2021; 5(4): 378-390. doi:10.7150/ntno.54879
[Abstract] [Full text] [PDF]

CFP - Special Issue: Osteoarthritis Theranostics. Guest Editors: Dr. WEN, CHUNYI, Dr. Magali Cucchiarini.
CFP - Special Issue: Extracellular vesicles in pathogenesis, diagnosis, or therapeutics of human diseases. Guest Editor: Ming-Lin Liu, Perelman School of Medicine, University of Pennsylvania.
Special Issue: Noble-metal Nanostructures for Theranostics. Guest Editors: Xiaohu Xia, University of Central Florida and Hui Wei, Nanjing University
Special Issue Targeting the Cancer Stem Cells. Guest Editor: Fei Chen, PhD, Professor, Wayne State University
Special Issue Progress in Gene Editing Nanotheranostics. Guest Editors: Gang Han (University of Massachusetts Medical School), Wen Xue (University of Massachusetts Medical School), Qiaobing Xu (Tufts University)
Special Issue Progress in Supramolecular Nanotheranostics. Guest Editors: Xiaoyuan (Shawn) Chen (NIBIB/NIH); Gang Zheng (University of Toronto); Jianjun Cheng (University of Illinois Urbana-Champaign); Yi-Yan Yang (Institute of Bioengineering and Nanotechnology, Singapore)

Congratulations to Dr. Chen for being elected as AIMBE fellow: https://aimbe.org/college-of-fellows/cof-2103/

Dr. Chen was recognized as Selected Highly Prolific Authors  (most published articles in the past 5 years) for 3 ACS journals (ACS Nano, Bioconjugate Chemistry, and Molecular Pharmaceutics). More details: http://journalstars.acs.org/

Dr. Chen received the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.

NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Published Special Issues