Theranostics
13.3
Impact Factor
23.90
CiteScore
< 5 days
First Decision
Global reach, higher impact
Theranostics 2012; 2(2):139-147. doi:10.7150/thno.3696 This issue Cite
Review
Enzymatic Self-Assembly of Nanostructures for Theranostics
CAS Key Laboratory of Soft Matter Chemistry, Department of Chemistry, University of Science and Technology of China, 96 Jinzhai Road, Hefei, Anhui 230026, China
Citation:
Chen Y, Liang G. Enzymatic Self-Assembly of Nanostructures for Theranostics. Theranostics 2012; 2(2):139-147. doi:10.7150/thno.3696. https://www.thno.org/v02p0139.htm
Other stylesAbstract
Self-assembly of small molecules or macromolecules through non-covalent or covalent bonds to build up supramolecular nanostructures is a prevalent and important process in nature. While most chemists use small molecules to assemble nanostructures with physical or chemical perturbations, nature adopts enzymes to catalyze the reaction to assemble biological, functional nanostructures with high efficiency and specificity. Although enzymatic self-assembly of nanostructures has been remained challenging for chemists, there are still a few examples of using important enzymes to initiate the self-assembly of nanostructures for diagnosis or therapy of certain diseases because down-regulation or overexpression of certain enzymes always associates with abnormalities of tissues/organs or diseases in living body. Herein, we introduce the concept of enzymatic self-assembly and illustrate the design and application of enzyme-catalyzed or -regulated formation of nanostructures for theranostics.
Keywords: Enzyme, Self-assembly, Nanostructures, Diagnosis, Therapy, Theranostics.
Citation styles
APA
Chen, Y., Liang, G. (2012). Enzymatic Self-Assembly of Nanostructures for Theranostics. Theranostics, 2(2), 139-147. https://doi.org/10.7150/thno.3696.
ACS
Chen, Y.; Liang, G. Enzymatic Self-Assembly of Nanostructures for Theranostics. Theranostics 2012, 2 (2), 139-147. DOI: 10.7150/thno.3696.
NLM
Chen Y, Liang G. Enzymatic Self-Assembly of Nanostructures for Theranostics. Theranostics 2012; 2(2):139-147. doi:10.7150/thno.3696. https://www.thno.org/v02p0139.htm
CSE
Chen Y, Liang G. 2012. Enzymatic Self-Assembly of Nanostructures for Theranostics. Theranostics. 2(2):139-147.
This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) License. See http://ivyspring.com/terms for full terms and conditions.