Theranostics 2023; 13(15):5183-5206. doi:10.7150/thno.85419 This issue Cite

Review

Aptamer-engineered (nano)materials for theranostic applications

Navid Rabiee1,2✉, Suxiang Chen1,2, Sepideh Ahmadi3,4, Rakesh N. Veedu1,2✉

1. Centre for Molecular Medicine and Innovative Therapeutics, Health Futures Institute, Murdoch University, Perth, WA 6150, Australia.
2. Perron Institute for Neurological and Translational Science, Perth, WA 6009, Australia.
3. Student Research Committee, Department of Medical Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
4. Cellular and Molecular Biology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Citation:
Rabiee N, Chen S, Ahmadi S, Veedu RN. Aptamer-engineered (nano)materials for theranostic applications. Theranostics 2023; 13(15):5183-5206. doi:10.7150/thno.85419. https://www.thno.org/v13p5183.htm
Other styles

File import instruction

Abstract

Graphic abstract

A diverse array of organic and inorganic materials, including nanomaterials, has been extensively employed in multifunctional biomedical applications. These applications encompass drug/gene delivery, tissue engineering, biosensors, photodynamic and photothermal therapy, and combinatorial sciences. Surface and bulk engineering of these materials, by incorporating biomolecules and aptamers, offers several advantages such as decreased cytotoxicity, improved stability, enhanced selectivity/sensitivity toward specific targets, and expanded multifunctional capabilities. In this comprehensive review, we specifically focus on aptamer-modified engineered materials for diverse biomedical applications. We delve into their mechanisms, advantages, and challenges, and provide an in-depth analysis of relevant literature references. This critical evaluation aims to enhance the scientific community's understanding of this field and inspire new ideas for future research endeavors.

Keywords: nanomaterials, aptamer, aptamer modified materials, biosensors, biomedical engineering


Citation styles

APA
Rabiee, N., Chen, S., Ahmadi, S., Veedu, R.N. (2023). Aptamer-engineered (nano)materials for theranostic applications. Theranostics, 13(15), 5183-5206. https://doi.org/10.7150/thno.85419.

ACS
Rabiee, N.; Chen, S.; Ahmadi, S.; Veedu, R.N. Aptamer-engineered (nano)materials for theranostic applications. Theranostics 2023, 13 (15), 5183-5206. DOI: 10.7150/thno.85419.

NLM
Rabiee N, Chen S, Ahmadi S, Veedu RN. Aptamer-engineered (nano)materials for theranostic applications. Theranostics 2023; 13(15):5183-5206. doi:10.7150/thno.85419. https://www.thno.org/v13p5183.htm

CSE
Rabiee N, Chen S, Ahmadi S, Veedu RN. 2023. Aptamer-engineered (nano)materials for theranostic applications. Theranostics. 13(15):5183-5206.

This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.
Popup Image