Theranostics 2020; 10(17):7836-7840. doi:10.7150/thno.48022


Interleukin-22 acts as a mitochondrial protector

Seonghwan Hwang, Dechun Feng, Bin Gao

Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892, USA.

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Hwang S, Feng D, Gao B. Interleukin-22 acts as a mitochondrial protector. Theranostics 2020; 10(17):7836-7840. doi:10.7150/thno.48022. Available from

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Interleukin (IL)-22 has been increasingly recognized as a promising therapeutic option for various types of diseases. This commentary summarizes the novel mechanistic aspects of IL-22 for the treatment of liver diseases including the study by Chen et al. published in the recent issue of the Theranostics that elucidated the novel function of IL-22 as a mitochondrial protector for the adaptive defense against liver injury.

Keywords: Interleukin (IL)-22, mitochondrial protector