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Volume 14 (17); 2024

Research Papers

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Whole-body fluorescence cryotomography identifies a fast-acting, high-contrast, durable contrast agent for fluorescence-guided surgery Augustino V. Scorzo, Brook K. Byrd, Caleb Y. Kwon, Rendall R. Strawbridge, Kimberley S. Samkoe, P. Jack Hoopes, Keith D. Paulsen, David W. Roberts, Scott C. Davis Theranostics 2024; 14(17): 6426-6445. doi:10.7150/thno.100802 Full text PDF PubMed PMC

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Mitochondrial transfer balances cell redox, energy and metabolic homeostasis in the osteoarthritic chondrocyte preserving cartilage integrity Angela C. Court, Ana María Vega-Letter, Eliseo Parra-Crisóstomo, Francesca Velarde, Cynthia García, Alexander Ortoloff, Rolando Vernal, Carolina Pradenas, Patricia Luz-Crawford, Maroun Khoury, Fernando E. Figueroa Theranostics 2024; 14(17): 6471-6486. doi:10.7150/thno.96723 Full text PDF PubMed PMC

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Targeting the smooth muscle cell Keap1-Nrf2-GSDMD-pyroptosis axis by cryptotanshinone prevents abdominal aortic aneurysm formation Jiaojiao Wang, Weile Ye, Jiami Zou, Pinglian Yang, Mei Jin, Zhihua Zheng, Chunhong Zhou, Wanlu Qiu, Jing Lu, Chengzhi Li, Shuai Guo, Yiming Xu, Zunnan Huang, Peiqing Liu, Zhiping Liu Theranostics 2024; 14(17): 6516-6542. doi:10.7150/thno.98400 Full text PDF PubMed PMC

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SPOP downregulation promotes bladder cancer progression based on cancer cell-macrophage crosstalk via STAT3/CCL2/IL-6 axis and is regulated by VEZF1 Meiqian Li, Yangyan Cui, Qi Qi, Jiakuan Liu, Jiaxuan Li, Guifang Huang, Jiale Yang, Jingya Sun, Zhihui Ma, Shengjie Liang, Dianzheng Zhang, Jun Jiang, Rujian Zhu, Qiuli Liu, Ruimin Huang, Jun Yan Theranostics 2024; 14(17): 6543-6559. doi:10.7150/thno.101575 Full text PDF PubMed PMC

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Supramolecularly engineered bacteria mediated calcium overload and immunotherapy of tumors Beibei Xie, Linmiao Dong, Leo Wang, Ruibing Wang, Chunlai Li Theranostics 2024; 14(17): 6560-6570. doi:10.7150/thno.99931 Full text PDF PubMed PMC

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Biomineralized in situ catalytic nanoreactor integrated microneedle patch for on demand immunomodulator supply to combat psoriasis Xiaodie Li, Minglong Chen, Xinni He, Jinghang Cong, Wanchen Zhao, Yanping Fu, Chao Lu, Chuanbin Wu, Xin Pan, Guilan Quan Theranostics 2024; 14(17): 6571-6586. doi:10.7150/thno.101845 Full text PDF PubMed PMC

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Tumor-derived EV miRNA signatures surpass total EV miRNA in supplementing mammography for precision breast cancer diagnosis Young Kim, Jee Ye Kim, Sol Moon, Hyojung Lee, Suji Lee, Joon Ye Kim, Min Woo Kim, Seung Il Kim Theranostics 2024; 14(17): 6587-6604. doi:10.7150/thno.99245 Full text PDF PubMed PMC

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Hypothalamic P62 (SQSTM1) regulates energy balance by modulating leptin signaling Shan Yang, Yang Li, Mingyuan Tian, Wuquan Deng, Dongfang Liu, Chen Chen, Zhiming Zhu, Hongting Zheng, Gangyi Yang, Ling Li, Mengliu Yang Theranostics 2024; 14(17): 6605-6624. doi:10.7150/thno.96480 Full text PDF PubMed PMC

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Brain-to-heart cholinergic synapse-calcium signaling mediates ischemic stroke-induced atrial fibrillation Yingran Liang, Gongxin Wang, Siwen Fan, Junyi Zhang, Shuang He, Guixiang Pan, Guoliang Hao, Yan Zhu Theranostics 2024; 14(17): 6625-6651. doi:10.7150/thno.99065 Full text PDF PubMed PMC

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Macrophage membrane‒biomimetic nanoparticles target inflammatory microenvironment for epilepsy treatment Chao Geng, Xinghui Ren, Peipei Cao, Xiaoqi Chu, Penghu Wei, Quanlei Liu, Yongchang Lu, Bin Fu, Wenyou Li, Yuhao Li, Guoguang Zhao Theranostics 2024; 14(17): 6652-6670. doi:10.7150/thno.99260 Full text PDF PubMed PMC

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Lactoferrin docking NIR-II cyanine dye as a potentiated phototheranostic for synchronous multimodal bioimaging and tumor photo-immunotherapy Lifeng Hang, Haijian Li, Meng Li, Yiqiang Sun, Wenjiao Wu, Laiping Fang, Yanzhao Diao, Hong Qu, Tao Zhang, Shumei Li, Guihua Jiang Theranostics 2024; 14(17): 6671-6691. doi:10.7150/thno.102663 Full text PDF PubMed PMC

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Platelets camouflaged nanovehicle improved bladder cancer immunotherapy by triggering pyroptosis Jiale Tian, Mingde Gao, Jinfeng Zhu, Haifei Xu, Hao Ji, Donglin Xia, Xiaolin Wang Theranostics 2024; 14(17): 6692-6707. doi:10.7150/thno.99040 Full text PDF PubMed PMC

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Intracalvariosseous administration of donepezil microspheres protects against cognitive impairment by virtue of long-lasting brain exposure in mice Ji Hee Kang, Jin-Kyoung Yang, Kyo Hee Cho, O Hyun Lee, Hayoon Kwon, Sun Yeou Kim, Sehoon Kim, Young Tag Ko Theranostics 2024; 14(17): 6708-6725. doi:10.7150/thno.100986 Full text PDF PubMed PMC

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Role of damaged mitochondrial transfer in alpha-particle generator 212Pb radiation-induced bystander effect Mengdie Yang, Lusheng Wang, Shanshan Qin, Xiongxin Dai, Jianguo Li, Liwei An, Lijuan Song, Jie Gao, Zongtai Han, Fei Yu Theranostics 2024; 14(17): 6768-6782. doi:10.7150/thno.101922 Full text PDF PubMed PMC

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Low hepatic artery blood flow mediates NET extravasation through the regulation of PIEZO1/SRC signaling to induce biliary complications after liver transplantation Hongqiang Yu, Yujun Zhang, Ling Shuai, Cong Peng, Changchun Zhao, Yan Jiang, Ling Yao, Jiejuan Lai, Zhiyu Chen, Leida Zhang, Xiang Xiong, Xiaojun Wang Theranostics 2024; 14(17): 6783-6797. doi:10.7150/thno.99514 Full text PDF PubMed PMC

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DNASE1L3-mediated PANoptosis enhances the efficacy of combination therapy for advanced hepatocellular carcinoma Jingchun Wang, Yu Chen, Yanquan Xu, Jiangang Zhang, Shuai Yang, Yu Zhou, Juan Lei, Ran Ren, Yang Chen, Huakan Zhao, Yongsheng Li, Shiming Yang Theranostics 2024; 14(17): 6798-6817. doi:10.7150/thno.102995 Full text PDF PubMed PMC

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Real-time monitoring of single dendritic cell maturation using deep learning-assisted surface-enhanced Raman spectroscopy Cai Zhang, Mengling Wang, Houde Wu, Hongmei Gao, Pengyun Wu, Li Guo, Dingbin Liu Theranostics 2024; 14(17): 6818-6830. doi:10.7150/thno.100298 Full text PDF PubMed PMC

Reviews

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Aspects and prospects of preclinical theranostic radiopharmaceutical development Bryce J.B. Nelson, Viktoria Krol, Aditya Bansal, Jan D. Andersson, Frank Wuest, Mukesh K. Pandey Theranostics 2024; 14(17): 6446-6470. doi:10.7150/thno.100339 Full text PDF PubMed PMC

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Engineering mesenchymal stem cells for premature ovarian failure: overcoming challenges and innovating therapeutic strategies Zijun Yuan, Yinping Zhang, Xinyu He, Xiang Wang, Xingyue Wang, Siqi Ren, Jiahong Su, Jing Shen, Xiang Li, Zhangang Xiao Theranostics 2024; 14(17): 6487-6515. doi:10.7150/thno.102641 Full text PDF PubMed PMC

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Targeting sirtuins for cancer therapy: epigenetics modifications and beyond Hui Shen, Xinyi Qi, Yue Hu, Yi Wang, Jin Zhang, Zhongyu Liu, Zheng Qin Theranostics 2024; 14(17): 6726-6767. doi:10.7150/thno.100667 Full text PDF PubMed PMC

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Harnessing glucose metabolism with nanomedicine for cancer treatment Xudong Wang, Liping Wang, Qingyi Hao, Meng Cai, Xueting Wang, Wenlin An Theranostics 2024; 14(17): 6831-6882. doi:10.7150/thno.100036 Full text PDF PubMed PMC

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