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Volume 16 (16); 2026

Research Papers

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mRNA-dendritic cell antigen vaccine potentiates CD38 CAR-T Cell therapy for relapsed/refractory acute myeloid leukemia Yu Lu, Xin Cai, Yanhui Li, Yuyuan Lv, Yutong Tang, Yuanyuan Li, Jiazi Zhou, Ailin Zhang, Pengchen Gu, Ziyi Hao, Qingya Cui, Jianhong Chu, Depei Wu, Xiaowen Tang Theranostics 2026; 16(16): 9061-9079. doi:10.7150/thno.139339 Full text PDF


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Visualizing the distribution of durvalumab targeting PD-L1 using quantitative fluorescence imaging in patients with esophageal cancer Anne M. van der Waaij, Ymke J. van Ginkel, Pia Volkmer, Gursah Kats-Ugurlu, Henrik K. Huizinga, Sara Hone Lopez, Jacco J. de Haan, Rina Bijlsma, Laurens A. van der Waaij, Christina T. Muijs, Anne G.H. Niezink, Boudewijn van Etten, Jessie Westerhof, Massimiliano di Pietro, Dominic J. Robinson, Marjolijn N. Lub-de Hooge, Wouter B. Nagengast Theranostics 2026; 16(16): 9080-9092. doi:10.7150/thno.136523 Full text PDF


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Oral inulin prebiotic encapsulating Cortex Fraxini extracellular vesicles alleviates colitis and associated renal stress via reinforcing intestinal barriers and remodeling microbiota Meihong Chai, Junlong Fu, Mengjie Zhang, Xing Pei, Xingzhou Liu, Bing Xiao, Bowen Gao, Jingya Wei, Baosen Yue, Mingxin Zhang, Mingzhen Zhang, Juan Jin Theranostics 2026; 16(16): 9093-9112. doi:10.7150/thno.139484 Full text PDF


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A nanoengineered MSC therapeutic for synergistic therapy of lupus nephritis via cfDNA clearance and targeted immunomodulation Jiang Tian, Qinyao Xu, Zexin Wang, Zeyu Wang, Haofang Zhu, Lingyun Sun, Zhongwei Gu Theranostics 2026; 16(16): 9145-9164. doi:10.7150/thno.136356 Full text PDF


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DCTN2 inhibited cellular senescence through targeting TRIM21 mediated MST2 ubiquitination and activation in hepatocellular carcinoma Yanbo Wang, Yaomei He, Qin Yu, Ningrui Wang, Qiaoling Ruan, Haiyan Wang, Hanqing Zhao, Yonglin Zhang, Yang Ke, Caie Tang, Liqi Lang, Yuxia Tang, Lixia Liu, Hao Zhang, Shan Yan, Aimin Wang, Qiushuo Shen, Ceshi Chen Theranostics 2026; 16(16): 9165-9184. doi:10.7150/thno.137790 Full text PDF


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Triple glutathione depletion-augmented disulfide and lipid peroxide accumulation to potentiate disulfidptosis and ferroptosis Shulin Du, Moyi Zhang, Hao Zheng, Ran Gao, Jinrong Chen, Rouyu Lin, Jing Li, Mengsi Zhang, Hao Zhang Theranostics 2026; 16(16): 9185-9199. doi:10.7150/thno.137256 Full text PDF


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Scalable manufacturing of human iPSC-derived functional liver organoids for acute liver failure treatment Xiaoshan Deng, Yunzhong Nie, Yoshihito Hayashi, Na Luo, Yang Li, Riana Plummer, Qinglin Li, Toshiharu Kasai, Takashi Okumura, Yu Kamishibahara, Takemasa Komoto, Takuya Ohkuma, Yasuhiro Yamada, Yumiko Isobe, Kiyoshi Yamaguchi, Satoshi Okamoto, Yasuharu Ueno, Naoki Tanimizu, Yoichi Furukawa, Hideki Taniguchi Theranostics 2026; 16(16): 9277-9294. doi:10.7150/thno.137714 Full text PDF


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ARG2 drives osteoblast senescence by repressing mitophagy via the IκB–NF-κB–TXN2 signaling axis: implications for age-associated osteoporosis Jinli Li, Liyao Zhang, Yuanyuan Ren, Junxuan Wang, Pan Zhang, Qianran Shen, Yaqi Wang, Yi Yu, Zi Cheng, Qiang Wang, Haiying Wang, Yuyan Xiong Theranostics 2026; 16(16): 9295-9321. doi:10.7150/thno.129818 Full text PDF


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Early micro- and nanoscale microglial responses to blood–brain barrier modulation by transcranial focused ultrasound Elisa Gonçalves de Andrade, Jared VanderZwaag, Rikke Hahn Kofoed, Katherine Picard, Keelin Henderson Pekarik, Micaël Carrier, Fernando González Ibáñez, Mohammadparsa Khakpour, Kullervo Hynynen, Isabelle Aubert, Marie-Ève Tremblay Theranostics 2026; 16(16): 9322-9345. doi:10.7150/thno.131051 Full text PDF


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A dual CEST-fluorescent reporter enables cross-validated tracking of hematopoietic engraftment in deep bone marrow Tehila Alter, Narmeen Haj, Doaa Ali-Naffaa, Maya Rom, Ramez Daniel, Galit Saar, Assaf A. Gilad, Katrien Vandoorne Theranostics 2026; 16(16): 9416-9433. doi:10.7150/thno.140697 Full text PDF

Reviews

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Targeted molecular CT imaging of atherosclerosis and abdominal aortic aneurysm Jannis Marchand, Felix Stefan Reuter, Hannah Lichtmannegger, Keno Kyrill Bressem, Lisa Christine Adams, Franz Pfeiffer, Avan Kader, Marcus Richard Makowski Theranostics 2026; 16(16): 9041-9060. doi:10.7150/thno.137688 Full text PDF


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Atherosclerosis nanotheranostics: a perspective from macrophages Caiyan Zhao, Jiakun Zhang, Rujie Wang, Shen’ao Wang, Hongzhang Deng Theranostics 2026; 16(16): 9113-9144. doi:10.7150/thno.121239 Full text PDF


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Cell-derived biomimetic nanomedicines: Emerging theranostic platforms for precision management of atherosclerosis Xingji Liu, Zhiyue Wang, Jiaqi Lu, Jie Sheng, Longjiang Zhang Theranostics 2026; 16(16): 9200-9220. doi:10.7150/thno.133733 Full text PDF


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Ultrasound-induced luminescence imaging for deep tissues Qiuyu Cheng, Jinlan Luo, Yandi Tan, Tong Xu, Yufeng Sun, Rui Geng, Hanbin Xu, Xiangmin Zhang, Lingwen Ding, Gege Wu, Xinwu Cui, Yijing Liu Theranostics 2026; 16(16): 9221-9260. doi:10.7150/thno.133393 Full text PDF


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Hybrid exosome–liposome nanovesicles as delivery platforms for therapeutic applications: merging the best of both worlds Jian Yu, Lujiao Yu, Fei Ren, Kai Cui, Gongping Sun, Hong Pan Theranostics 2026; 16(16): 9261-9276. doi:10.7150/thno.135691 Full text PDF


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Organelle-targeted precision cancer theranostics: From molecular design to NIR-II imaging Dandan Chen, Beiling Zheng, Zhixiang Lu, Yaohui He, Pengfei Lyu Theranostics 2026; 16(16): 9346-9383. doi:10.7150/thno.137525 Full text PDF


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Recent advances in CRISPR technologies for biomedical applications and disease treatment Xue Wu, Xiaorong Kou, Liping Bai, Chao Liu, Qinjie Wu, Ming Zhang, Ning Wang, Changyang Gong Theranostics 2026; 16(16): 9384-9415. doi:10.7150/thno.136062 Full text PDF


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Harnessing ultrasound-responsive technologies for precision periodontitis therapy: a perspective Chao Xing, Sibtain Muhammad, Bing Guo Theranostics 2026; 16(16): 9434-9483. doi:10.7150/thno.138283 Full text PDF

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