Theranostics 2018; 8(22):6355-6356. doi:10.7150/thno.30953 This issue Cite

Editorial

Deficiency of TLR4 ameliorates hypoperfusion-induced brain pathology

Yang Liu1,2,3✉, Klaus Fassbender1,2

1. Department of Neurology, Saarland University, 66421 Homburg, Germany;
2. German Institute for Dementia Prevention (DIDP), Saarland University, 66421 Homburg, Germany
3. Department of Clinical Laboratory, Tongji Hospital, Tongji University Medical School, 200065 Shanghai, China

Citation:
Liu Y, Fassbender K. Deficiency of TLR4 ameliorates hypoperfusion-induced brain pathology. Theranostics 2018; 8(22):6355-6356. doi:10.7150/thno.30953. https://www.thno.org/v08p6355.htm
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Commentary-article in Theranostics, Volume 8, 5434

Abstract

Microglial inflammatory activation contributes to chronic cerebral hypoperfusion-induced brain pathology. This editorial highlights a study by Qin et al. (Theranostics 2018; 8(19):5434-5451. doi:10.7150/thno.27882) that deficiency of TLR4 attenuates cognitive dysfunction and white matter injury by reducing autophagy and pro-inflammatory activation in microglia.

Keywords: chronic cerebral hypoperfusion, microglia, inflammation, autophagy, TLR4.


Citation styles

APA
Liu, Y., Fassbender, K. (2018). Deficiency of TLR4 ameliorates hypoperfusion-induced brain pathology. Theranostics, 8(22), 6355-6356. https://doi.org/10.7150/thno.30953.

ACS
Liu, Y.; Fassbender, K. Deficiency of TLR4 ameliorates hypoperfusion-induced brain pathology. Theranostics 2018, 8 (22), 6355-6356. DOI: 10.7150/thno.30953.

NLM
Liu Y, Fassbender K. Deficiency of TLR4 ameliorates hypoperfusion-induced brain pathology. Theranostics 2018; 8(22):6355-6356. doi:10.7150/thno.30953. https://www.thno.org/v08p6355.htm

CSE
Liu Y, Fassbender K. 2018. Deficiency of TLR4 ameliorates hypoperfusion-induced brain pathology. Theranostics. 8(22):6355-6356.

This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) license (https://creativecommons.org/licenses/by-nc/4.0/). See http://ivyspring.com/terms for full terms and conditions.
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