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Volume 16 (12); 2026

Research Papers

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Scalable differentiation of human cardiac organoids from iPSCs generates cardiac tissues for cardiac cell therapy Sarkawt Hamad, Ebru Aksoy, Maria Kalil, Daina Martínez-Falguera, Christian Jüngst, Katharina Zahn, Felix Gaedke, Gabriel Peinkofer, Bastiaan J Boukens, Rezwan Firuzi, Rebecca Prause, Julia Aranyo, Felipe Bisbal, Oriol Iborra-Egea, Esther Jorge, Georgina Iraola-Picornell, Albert Teis, Martina de Raffele, Victoria Delgado, Frank Nitsche, Agapios Sachinidis, Markus Khalil, Fatma Alhashimi, Astrid Schauss, Antoni Bayes-Genis, Carolina Gálvez-Montón, Kurt P Pfannkuche Theranostics 2026; 16(12): 6437-6462. doi:10.7150/thno.127654 Full text PDF


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Development and in vivo evaluation of 18F-labeled PET tracers covalently targeting KRAS-G12C for noninvasive cancer diagnosis and therapy monitoring Michael Willmann, Jens P. Bankstahl, Frank M. Bengel, Christine Drechsler, Christina Esdar, Kathrin Gläser, Andrea U. Lopez, Tatjana Ross, Hanno Schieferstein, Tobias L. Ross Theranostics 2026; 16(12): 6485-6496. doi:10.7150/thno.123741 Full text PDF


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Localized and sustained release of Botulinum Toxin A from supramolecular peptide hydrogel for strabismus treatment Wei Guo, Hui Zhu, Yuchen Yao, Dan Huang, Tiantian Zhou, Xiaoqi Zhu, Jiaying Zhang, Gaolin Liang, Wenjun Zhan, Hu Liu Theranostics 2026; 16(12): 6497-6508. doi:10.7150/thno.128115 Full text PDF


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On-demand sIPN microneedles promote infected burn wound healing via microenvironment remodeling and activation of the Wnt–KLF5 regenerative axis Xiang Fang, Boquan Qin, Aaron Qi Zhang, Zhiyuan Zhang, Tingli Wang, Shizhou Wu, Hui Zhang, Hong Duan Theranostics 2026; 16(12): 6509-6528. doi:10.7150/thno.130253 Full text PDF


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A dual functional theranostic microneedle patch for immunomodulation and real time monitoring in diabetic wound therapy Shuai Fan, Junlong Zhong, Yeke Chen, Kang Chen, Zhiming Liu, Xinmin Yang, Wen Tan, Wenlong Tang, Wanhui Zhou, Degui Wu, Jiachao Xiong, Zhenhai Zhou, Fanrong Ai, Kai Cao Theranostics 2026; 16(12): 6529-6553. doi:10.7150/thno.133451 Full text PDF


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Mitochondria-targeting organoselenium theranostic radioprotectors for simultaneous treatment and imaging of radiation-induced liver injury Zifei Wu, Xie Huang, Mingquan Gao, Liting Wang, Zaizhi Du, Ziqian Shang, Xudong Yu, Xiaojiao Wang, Shuyue Deng, Xinrui Yang, Binghui Lu, Jing Liu, Weidong Wang, Rong Li, Shenglin Luo Theranostics 2026; 16(12): 6554-6575. doi:10.7150/thno.133714 Full text PDF

Reviews

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Human Multi-Organ-on-a-Chip Platforms for Next-Generation Drug Delivery Strategies Cosmo S. Mitchell, Hong-Il Yoo, Carolina Gracia Diaz, Jordan J. Green, Deok-Ho Kim Theranostics 2026; 16(12): 6463-6484. doi:10.7150/thno.130030 Full text PDF


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The CXCR4-targeted theranostics era: a comprehensive review of a decade of progress (2015–2025) Biao Yang, Wenzhu Hu, Xiao Zhang, Yongkang Gai, Rui An, Chunxia Qin, Mengting Li, Xiaoli Lan Theranostics 2026; 16(12): 6576-6599. doi:10.7150/thno.130266 Full text PDF


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Bacterial extracellular vesicles as multifaceted regulators of human diseases and emerging therapeutic platforms Jing Wang, Shuwen Wang, Yanzheng Wang, Ting Zhang, Xu Zhang Theranostics 2026; 16(12): 6600-6633. doi:10.7150/thno.132287 Full text PDF


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Functionalized metallic nanomaterials, nanozymes and nanomotors for emerging tumor diagnosis and treatment: from design to theranostics strategies Ze Wang, Dongzhou Wang, Bingya Zhang, Tong Sha, Di You, Mikhail I. Voevoda, Guokun Zhang, Bai Yang, Wenlai Guo, Quan Lin, Wenrui Qu Theranostics 2026; 16(12): 6634-6670. doi:10.7150/thno.131873 Full text PDF


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Efferocytosis in heart failure: Mechanisms, dysregulation and therapeutic potential Otega Oviri, Shijie Liu, Hongye Huang, Xiaoyuan Bai, Jingke Yao, Zufeng Ding Theranostics 2026; 16(12): 6671-6690. doi:10.7150/thno.132477 Full text PDF

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