Theranostics 2020; 10(9):4277-4289. doi:10.7150/thno.40249 This issue Cite

Review

Quantitative ultrasound approaches for diagnosis and monitoring hepatic steatosis in nonalcoholic fatty liver disease

Amir M. Pirmoazen1, Aman Khurana2, Ahmed El Kaffas3, Aya Kamaya1✉

1. Department of Radiology, School of Medicine, Stanford University, Stanford, California
2. Department of Radiology, University of Kentucky, Lexington, Kentucky
3. Department of Radiology, Molecular Imaging Program at Stanford, School of Medicine, Stanford University, Stanford, California

Citation:
Pirmoazen AM, Khurana A, El Kaffas A, Kamaya A. Quantitative ultrasound approaches for diagnosis and monitoring hepatic steatosis in nonalcoholic fatty liver disease. Theranostics 2020; 10(9):4277-4289. doi:10.7150/thno.40249. https://www.thno.org/v10p4277.htm
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Abstract

Graphic abstract

Nonalcoholic fatty liver disease is a major global health concern with increasing prevalence, associated with obesity and metabolic syndrome. Recently, quantitative ultrasound-based imaging techniques have dramatically improved the ability of ultrasound to detect and quantify hepatic steatosis. These newer ultrasound techniques possess many inherent advantages similar to conventional ultrasound such as universal availability, real-time capability, and relatively low cost along with quantitative rather than a qualitative assessment of liver fat. In addition, quantitative ultrasound-based imaging techniques are less operator dependent than traditional ultrasound. Here we review several different emerging quantitative ultrasound-based approaches used for detection and quantification of hepatic steatosis in patients at risk for nonalcoholic fatty liver disease. We also briefly summarize other clinically available imaging modalities for evaluating hepatic steatosis such as MRI, CT, and serum analysis.

Keywords: nonalcoholic fatty liver disease, nonalcoholic steatohepatitis, quantitative ultrasound, noninvasive assessment, hepatic steatosis


Citation styles

APA
Pirmoazen, A.M., Khurana, A., El Kaffas, A., Kamaya, A. (2020). Quantitative ultrasound approaches for diagnosis and monitoring hepatic steatosis in nonalcoholic fatty liver disease. Theranostics, 10(9), 4277-4289. https://doi.org/10.7150/thno.40249.

ACS
Pirmoazen, A.M.; Khurana, A.; El Kaffas, A.; Kamaya, A. Quantitative ultrasound approaches for diagnosis and monitoring hepatic steatosis in nonalcoholic fatty liver disease. Theranostics 2020, 10 (9), 4277-4289. DOI: 10.7150/thno.40249.

NLM
Pirmoazen AM, Khurana A, El Kaffas A, Kamaya A. Quantitative ultrasound approaches for diagnosis and monitoring hepatic steatosis in nonalcoholic fatty liver disease. Theranostics 2020; 10(9):4277-4289. doi:10.7150/thno.40249. https://www.thno.org/v10p4277.htm

CSE
Pirmoazen AM, Khurana A, El Kaffas A, Kamaya A. 2020. Quantitative ultrasound approaches for diagnosis and monitoring hepatic steatosis in nonalcoholic fatty liver disease. Theranostics. 10(9):4277-4289.

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