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Volume 10 (8); 2020

Research Papers

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Targeting GRP78-dependent AR-V7 protein degradation overcomes castration-resistance in prostate cancer therapy
Yuning Liao, Yuan Liu, Xiaohong Xia, Zhenlong Shao, Chuyi Huang, Jinchan He, Lili Jiang, Daolin Tang, Jinbao Liu, Hongbiao Huang
Theranostics 2020; 10(8): 3366-3381. doi:10.7150/thno.41849
[Abstract] [Full text] [PDF]


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N6-methyladenosine-induced ERRγ triggers chemoresistance of cancer cells through upregulation of ABCB1 and metabolic reprogramming
Zhuojia Chen, Long Wu, Jiawang Zhou, Xinyao Lin, Yanxi Peng, Lichen Ge, Cheng-Ming Chiang, Hui Huang, Hongsheng Wang, Weiling He
Theranostics 2020; 10(8): 3382-3396. doi:10.7150/thno.40144
[Abstract] [Full text] [PDF]


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Novel calreticulin-nanoparticle in combination with focused ultrasound induces immunogenic cell death in melanoma to enhance antitumor immunity
Sri Nandhini Sethuraman, Mohit Pratap Singh, Girish Patil, Shitao Li, Steven Fiering, P. Jack Hoopes, Chandan Guha, Jerry Malayer, Ashish Ranjan
Theranostics 2020; 10(8): 3397-3412. doi:10.7150/thno.42243
[Abstract] [Full text] [PDF]


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Tuned near infrared fluorescent hyaluronic acid conjugates for delivery to pancreatic cancer for intraoperative imaging
Bowen Qi, Ayrianne J. Crawford, Nicholas E. Wojtynek, Geoffrey A. Talmon, Michael A. Hollingsworth, Quan P. Ly, Aaron M. Mohs
Theranostics 2020; 10(8): 3413-3429. doi:10.7150/thno.40688
[Abstract] [Full text] [PDF]


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Smart Sorting of Tumor Phenotype with Versatile Fluorescent Ag Nanoclusters by Sensing Specific Reactive Oxygen Species
Xin Chen, Tiegong Wang, Wenjun Le, Xin Huang, Minghui Gao, Qian Chen, Shuogui Xu, Detao Yin, Qingge Fu, Chengwei Shao, Bingdi Chen, Donglu Shi
Theranostics 2020; 10(8): 3430-3450. doi:10.7150/thno.38422
[Abstract] [Full text] [PDF]


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A hypermethylation strategy utilized by enhancer-bound CARM1 to promote estrogen receptor α-dependent transcriptional activation and breast carcinogenesis
Bing-ling Peng, Wen-juan Li, Jian-cheng Ding, Yao-hui He, Ting Ran, Bing-lan Xie, Zi-rui Wang, Hai-feng Shen, Rong-quan Xiao, Wei-wei Gao, Tian-yi Ye, Xiang Gao, Wen Liu
Theranostics 2020; 10(8): 3451-3473. doi:10.7150/thno.39241
[Abstract] [Full text] [PDF]


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Tumor cell-derived exosomes home to their cells of origin and can be used as Trojan horses to deliver cancer drugs
Li Qiao, Shiqi Hu, Ke Huang, Teng Su, Zhenhua Li, Adam Vandergriff, Jhon Cores, Phuong-Uyen Dinh, Tyler Allen, Deliang Shen, Hongxia Liang, Yongjun Li, Ke Cheng
Theranostics 2020; 10(8): 3474-3487. doi:10.7150/thno.39434
[Abstract] [Full text] [PDF]


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Metabolic remodeling by TIGAR overexpression is a therapeutic target in esophageal squamous-cell carcinoma
Jiahui Chu, Xiangjie Niu, Jiang Chang, Mingming Shao, Linna Peng, Yiyi Xi, Ai Lin, Chengcheng Wang, Qionghua Cui, Yingying Luo, Wenyi Fan, Yamei Chen, Yanxia Sun, Wenjia Guo, Wen Tan, Dongxin Lin, Chen Wu
Theranostics 2020; 10(8): 3488-3502. doi:10.7150/thno.41427
[Abstract] [Full text] [PDF]


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Concurrent imaging of vascularization and metabolism in a mouse model of paraganglioma under anti-angiogenic treatment
Caterina Facchin, Mailyn Perez-Liva, Anikitos Garofalakis, Thomas Viel, Anais Certain, Daniel Balvay, Thulaciga Yoganathan, Justine Woszczyk, Kelly De Sousa, Joevin Sourdon, Jean Provost, Mickael Tanter, Charlotte Lussey-Lepoutre, Judith Favier, Bertrand Tavitian
Theranostics 2020; 10(8): 3518-3532. doi:10.7150/thno.40687
[Abstract] [Full text] [PDF]

Review

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Circular RNA-protein interactions: functions, mechanisms, and identification
Anqing Huang, Haoxiao Zheng, Zhiye Wu, Minsheng Chen, Yuli Huang
Theranostics 2020; 10(8): 3503-3517. doi:10.7150/thno.42174
[Abstract] [Full text] [PDF]