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Volume 14 (3); 2024
Research Papers
[89Zr]-CD8 ImmunoPET imaging of glioblastoma multiforme response to combination oncolytic viral and checkpoint inhibitor immunotherapy reveals CD8 infiltration differential changes in preclinical models Carlos A. Gallegos, Yun Lu, Jennifer C. Clements, Patrick N. Song, Shannon E. Lynch, Alessandro Mascioni, Fang Jia, Yolanda E. Hartman, Adriana V. F. Massicano, Hailey A. Houson, Suzanne E. Lapi, Jason M. Warram, James M. Markert, Anna G. Sorace
Theranostics 2024; 14(3): 911-923. doi:10.7150/thno.89206
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Macroscale pseudo-spheroids fabricated using methacrylated collagen-coated cells SooJung Chae, Hyeongjin Lee, Dongryeol Ryu, GeunHyung Kim
Theranostics 2024; 14(3): 924-939. doi:10.7150/thno.92193
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Endometrial organoids: a reservoir of functional mitochondria for uterine repair Sun-Young Hwang, Danbi Lee, Gaeun Lee, Jungho Ahn, Yu-Gyeong Lee, Hwa Seon Koo, Youn-Jung Kang
Theranostics 2024; 14(3): 954-972. doi:10.7150/thno.90538
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Deep learning for automatic organ and tumor segmentation in nanomedicine pharmacokinetics Alex Dhaliwal, Jun Ma, Mark Zheng, Qing Lyu, Maneesha A. Rajora, Shihao Ma, Laura Oliva, Anthony Ku, Michael Valic, Bo Wang, Gang Zheng
Theranostics 2024; 14(3): 973-987. doi:10.7150/thno.90246
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Palmitoylation of PKCδ by ZDHHC5 in hypothalamic microglia presents as a therapeutic target for fatty liver disease Yan-Hang Wang, Xin Chen, Yi-Zhen Bai, Peng Gao, Zhuo Yang, Qiang Guo, Ying-Yuan Lu, Jiao Zheng, Dan Liu, Jun Yang, Peng-Fei Tu, Ke-Wu Zeng
Theranostics 2024; 14(3): 988-1009. doi:10.7150/thno.89602
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Blockade of CD93 in pleural mesothelial cells fuels anti-lung tumor immune responses Chengyan Zhang, Xi Nan, Bei Zhang, Hao Wu, Xianchang Zeng, Zhengbo Song, Shumin Li, Jiaoli Wang, Shaofang Xie, Gensheng Zhang, Huiqing Xiu, Jianli Wang, Jufeng Guo, Pingli Wang, Zhijian Cai, Yunfang Zhen, Yingying Shen
Theranostics 2024; 14(3): 1010-1028. doi:10.7150/thno.89144
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Keratinocyte-to-macrophage communication exacerbate psoriasiform dermatitis via LRG1-enriched extracellular vesicles Wenjuan Jiang, Tingting Zhang, Yueqi Qiu, Qianmei Liu, Xiaoyun Chen, Qiaolin Wang, Xiaoli Min, Lianlian Ouyang, Sujie Jia, Qianjin Lu, Yuan He, Ming Zhao
Theranostics 2024; 14(3): 1049-1064. doi:10.7150/thno.89180
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Integrated analysis of single-cell and bulk transcriptomics develops a robust neuroendocrine cell-intrinsic signature to predict prostate cancer progression Tingting Zhang, Faming Zhao, Yahang Lin, Mingsheng Liu, Hongqing Zhou, Fengzhen Cui, Yang Jin, Liang Chen, Xia Sheng
Theranostics 2024; 14(3): 1065-1080. doi:10.7150/thno.92336
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Quantitative visualization of myocardial ischemia-reperfusion-induced cardiac lesions via ferroptosis magnetic particle imaging Wenwen Yang, Yueqi Wang, Changgeng Fu, Changjian Li, Feng Feng, Hongzheng Li, Ling Tan, Hua Qu, Hui Hui, Jingjing Wang, Jie Tian, Linzi Long
Theranostics 2024; 14(3): 1081-1097. doi:10.7150/thno.89190
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Morphine- and foot shock-responsive neuronal ensembles in the VTA possess different connectivity and biased GPCR signaling pathway Fan Wang, Chao-bao Liu, Yi Wang, Xi-xi Wang, Yuan-yao Yang, Chang-you Jiang, Qiu-min Le, Xing Liu, Lan Ma, Fei-fei Wang
Theranostics 2024; 14(3): 1126-1146. doi:10.7150/thno.90792
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Midline-1 regulates effector T cell motility in experimental autoimmune encephalomyelitis via mTOR/microtubule pathway Yingying Wei, Wenjuan Li, Jie Huang, Zachary Braunstein, Xinxin Liu, Xinlu Li, Jeffrey Deiuliis, Jun Chen, Xinwen Min, Handong Yang, Quan Gong, Leya He, Zheng Liu, Lingli Dong, Jixin Zhong
Theranostics 2024; 14(3): 1168-1180. doi:10.7150/thno.87130
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Discovery of novel antibacterial agent for the infected wound treatment: all-hydrocarbon stapling optimization of LL-37 Yanan Zhang, Mengjun Zheng, Zhe Wang, Zhinan Liu, Sumeng Chen, Xiang Li, Yejiao Shi, Honggang Hu
Theranostics 2024; 14(3): 1181-1194. doi:10.7150/thno.87916
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The combination of calreticulin-targeting L-ASNase and anti-PD-L1 antibody modulates the tumor immune microenvironment to synergistically enhance the antitumor efficacy of radiotherapy Ying Zhang, Venu Akhil, Ho Seong Seo, Hae Ran Park, Soo Hyun Kim, Sung-Hwan You, Zhipeng Liu, So-young Kim, Rukhsora D. Sultonova, Jung-Joon Min, Yeongjin Hong
Theranostics 2024; 14(3): 1195-1211. doi:10.7150/thno.90376
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A novel approach to guide GD2-targeted therapy in pediatric tumors by PET and [64Cu]Cu-NOTA-ch14.18/CHO Nils Florian Trautwein, Johannes Schwenck, Christian Seitz, Ferdinand Seith, Eduardo Calderón, Sebastian von Beschwitz, Stephan Singer, Gerald Reischl, Rupert Handgretinger, Jürgen Schäfer, Peter Lang, Bernd J. Pichler, Johannes H. Schulte, Christian la Fougère, Helmut Dittmann
Theranostics 2024; 14(3): 1212-1223. doi:10.7150/thno.92481
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Tumor cell senescence-induced macrophage CD73 expression is a critical metabolic immune checkpoint in the aging tumor microenvironment Yue Deng, Qinyan Chen, Xiao Yang, Yajie Sun, Bin Zhang, Wenwen Wei, Suke Deng, Jingshu Meng, Yan Hu, Yijun Wang, Zhanjie Zhang, Lu Wen, Fang Huang, Chao Wan, Kunyu Yang
Theranostics 2024; 14(3): 1224-1240. doi:10.7150/thno.91119
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Single-cell RNA sequencing reveals S100a9hi macrophages promote the transition from acute inflammation to fibrotic remodeling after myocardial ischemia‒reperfusion Shichun Shen, Meng Zhang, Xiaohe Wang, Qiaoling Liu, Huimin Su, Bingyi Sun, Zhiqing Guo, Beiduo Tian, Hong Gan, Chen Gong, Likun Ma
Theranostics 2024; 14(3): 1241-1259. doi:10.7150/thno.91180
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Gut ribotoxic stress responses facilitate dyslipidemia via metabolic reprogramming: an environmental health prediction Juil Kim, Hoyoung Jeong, Navin Ray, Ki-Hyung Kim, Yuseok Moon
Theranostics 2024; 14(3): 1289-1311. doi:10.7150/thno.88586
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Pattern recognition of microcirculation with super-resolution ultrasound imaging provides markers for early tumor response to anti-angiogenic therapy Jingyi Yin, Feihong Dong, Jian An, Tianyu Guo, Heping Cheng, Jiabin Zhang, Jue Zhang
Theranostics 2024; 14(3): 1312-1324. doi:10.7150/thno.89306
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Reviews
Peptide receptor radionuclide therapy combinations for neuroendocrine tumours in ongoing clinical trials: status 2023 Gianpaolo di Santo, Giulia Santo, Anna Sviridenko, Irene Virgolini
Theranostics 2024; 14(3): 940-953. doi:10.7150/thno.91268
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Antibacterial micro/nanomotors: current research progress, challenges, and opportunities Xin-Yang Liu, Rui-Fang Li, Jun Jia, Zi-Li Yu
Theranostics 2024; 14(3): 1029-1048. doi:10.7150/thno.92449
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Construction of tumor organoids and their application to cancer research and therapy Jiajing Lv, Xuan Du, Miaomiao Wang, Jiacan Su, Yan Wei, Can Xu
Theranostics 2024; 14(3): 1101-1125. doi:10.7150/thno.91362
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In situ vaccination caused by diverse irradiation-driven cell death programs Yijun Wang, Yan Li, Yuxin Yang, Michelle Swift, Zhenyu Zhang, Shuhui Wu, Yajie Sun, Kunyu Yang
Theranostics 2024; 14(3): 1147-1167. doi:10.7150/thno.86004
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Understanding AAV vector immunogenicity: from particle to patient Bijay P. Dhungel, Ian Winburn, Candida da Fonseca Pereira, Kui Huang, Amit Chhabra, John E. J. Rasko
Theranostics 2024; 14(3): 1260-1288. doi:10.7150/thno.89380
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Errata
Non-canonical signaling pathway of SNAI2 induces EMT in ovarian cancer cells by suppressing miR-222-3p transcription and upregulating PDCD10: Erratum Lili Fan, Han Lei, Sai Zhang, Yulong Peng, Chunyan Fu, Guang Shu, Gang Yin
Theranostics 2024; 14(3): 1098. doi:10.7150/thno.92973
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Acute cellular and vascular responses to photodynamic therapy using EGFR-targeted nanobody-photosensitizer conjugates studied with intravital optical imaging and magnetic resonance imaging: Erratum Henriette S. de Bruijn, Vida Mashayekhi, Tom J.L. Schreurs, Pieter B.A.A. van Driel, Gustav J. Strijkers, Paul J. van Diest, Clemens W.G.M. Lowik, Ann L.B. Seynhaeve, Timo L.M. ten Hagen, Jeanine J. Prompers, Paul M.P. van Bergen en Henegouwen, Dominic J. Robinson, Sabrina Oliveira
Theranostics 2024; 14(3): 1099-1100. doi:10.7150/thno.93248
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