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Volume 14 (6); 2024

Research Papers

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Programming peptide-oligonucleotide nano-assembly for engineering of neoantigen vaccine with potent immunogenicity Zhichu Xiang, Jianhua Lu, Shangrui Rao, Chenxing Fu, Yuying Yao, Yongdong Yi, Yang Ming, Weijian Sun, Weisheng Guo, Xiaoyuan Chen Theranostics 2024; 14(6): 2290-2303. doi:10.7150/thno.93395 Full text PDF PubMed PMC

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HDAC6-dependent deacetylation of NGF dictates its ubiquitination and maintains primordial follicle dormancy Tuo Zhang, Yuntong Tong, Rengguang Zhu, Yaoyun Liang, Jixian Zhang, Chujiao Hu, Meina He, Zhu Hu, Zhiyi Shen, Jin Niu, Jingjing Zhang, Yuanyuan Yu, Bangming Jin, Shan Lei, Zhirui Zeng, Yingmin Wu, Zengmei Cheng, Ziwen Xiao, Bing Guo, Shuyun Zhao, Guoqiang Xu, Wei Pan, Tengxiang Chen Theranostics 2024; 14(6): 2345-2366. doi:10.7150/thno.95164 Full text PDF PubMed PMC

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Hepatic progenitor cell-originated ductular reaction facilitates liver fibrosis through activation of hedgehog signaling Yonghong Hu, Xinyu Bao, Zheng Zhang, Long Chen, Yue Liang, Yan Qu, Qun Zhou, Xiaoxi Zhou, Jing Fang, Zhun Xiao, Yadong Fu, Hailin Yang, Wei Liu, Ying Lv, Hongyan Cao, Gaofeng Chen, Jian Ping, Hua Zhang, Yongping Mu, Chenghai Liu, Chao-Po Lin, Jian Wu, Ping Liu, Jiamei Chen Theranostics 2024; 14(6): 2379-2395. doi:10.7150/thno.91572 Full text PDF PubMed PMC

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Disturbed flow impairs MerTK-mediated efferocytosis in aortic endothelial cells during atherosclerosis Jinzi Wu, Shijie Liu, Oishani Banerjee, Hang Shi, Bingzhong Xue, Zufeng Ding Theranostics 2024; 14(6): 2427-2441. doi:10.7150/thno.93036 Full text PDF PubMed PMC

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The HSP90 inhibitor HVH-2930 exhibits potent efficacy against trastuzumab-resistant HER2-positive breast cancer Minsu Park, Eunsun Jung, Jung Min Park, Soeun Park, Dongmi Ko, Juyeon Seo, Seongjae Kim, Kee Dal Nam, Yong Koo Kang, Lee Farrand, Van-Hai Hoang, Cong-Truong Nguyen, Minh Thanh La, Gibeom Nam, Hyun-Ju Park, Jihyae Ann, Jeewoo Lee, Yoon-Jae Kim, Ji Young Kim, Jae Hong Seo Theranostics 2024; 14(6): 2442-2463. doi:10.7150/thno.93236 Full text PDF PubMed PMC

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Lipid nanoparticle encapsulated large peritoneal macrophages migrate to the lungs via the systemic circulation in a model of clodronate-mediated lung-resident macrophage depletion Dhaval Oza, Fernando Ivich, Joshua Pace, Mikyung Yu, Mark Niedre, Mansoor Amiji Theranostics 2024; 14(6): 2526-2543. doi:10.7150/thno.91062 Full text PDF PubMed PMC

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Mechanosensitive protein polycystin-1 promotes periosteal stem/progenitor cells osteochondral differentiation in fracture healing Ran Liu, Yu-Rui Jiao, Mei Huang, Nan-Yu Zou, Chen He, Min Huang, Kai-Xuan Chen, Wen-Zhen He, Ling Liu, Yu-Chen Sun, Zhu-Ying Xia, L. Darryl Quarles, Hai-Lin Yang, Wei-Shan Wang, Zhou-Sheng Xiao, Xiang-Hang Luo, Chang-Jun Li Theranostics 2024; 14(6): 2544-2559. doi:10.7150/thno.93269 Full text PDF PubMed PMC

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Exploring the role of combined external beam radiotherapy and targeted radioligand therapy with [177Lu]Lu-PSMA-617 for prostate cancer - from bench to bedside Daria Arbuznikova, Aikaterini Klotsotyra, Lisa Uhlmann, Lisa-Charlotte Domogalla, Nils Steinacker, Michael Mix, Gabriele Niedermann, Simon K.B. Spohn, Martin T. Freitag, Anca L. Grosu, Philipp T. Meyer, Christian Gratzke, Matthias Eder, Constantinos Zamboglou, Ann-Christin Eder Theranostics 2024; 14(6): 2560-2572. doi:10.7150/thno.93249 Full text PDF PubMed PMC

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Hypofractionated radiotherapy combined with lenalidomide improves systemic antitumor activity in mouse solid tumor models Kateryna Onyshchenko, Ren Luo, Xi Rao, Xuanwei Zhang, Simone Gaedicke, Anca-Ligia Grosu, Elke Firat, Gabriele Niedermann Theranostics 2024; 14(6): 2573-2588. doi:10.7150/thno.88864 Full text PDF PubMed PMC

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Siglec-F+ neutrophils in the spleen induce immunosuppression following acute infection Chaoxiong Liao, Shuhua Luo, Xiaolei Liu, Lina Zhang, Pengyun Xie, Wending Zhou, Yue Lu, Hanhui Zhong, Xuedi Zhang, Ziying Xiong, Xiao Huang, Guixi Mo, Daqing Ma, Jing Tang Theranostics 2024; 14(6): 2589-2604. doi:10.7150/thno.93812 Full text PDF PubMed PMC

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IL4 receptor targeting enables nab-paclitaxel to enhance reprogramming of M2-type macrophages into M1-like phenotype via ROS-HMGB1-TLR4 axis and inhibition of tumor growth and metastasis Sri Murugan Poongkavithai Vadevoo, Yeoul Kang, Gowri Rangaswamy Gunassekaran, Seok-Min Lee, Min-Sung Park, Dong Gyun Jo, Sang-Kyun Kim, Ho Lee, Won Jong Kim, Byungheon Lee Theranostics 2024; 14(6): 2605-2621. doi:10.7150/thno.92672 Full text PDF PubMed PMC

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NAD+ precursors promote the restoration of spermatogenesis in busulfan-treated mice through inhibiting Sirt2-regulated ferroptosis Yan-Qin Feng, Xuan Liu, Ning Zuo, Mu-Bin Yu, Wen-Meng Bian, Bao-Quan Han, Zhong-Yi Sun, Massimo De Felici, Wei Shen, Lan Li Theranostics 2024; 14(6): 2622-2636. doi:10.7150/thno.92416 Full text PDF PubMed PMC

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Size control of ropivacaine nano/micro-particles by soft-coating with peptide nanosheets for long-acting analgesia Jing Liu, Weiwei Wu, Fei Peng, Deying Gong, Yi Kang, Yujun Zhang, Congyan Liu, Yuncheng Li, Guoyan Zhao, Feng Qiu, Wensheng Zhang Theranostics 2024; 14(6): 2637-2655. doi:10.7150/thno.93322 Full text PDF PubMed PMC

Reviews

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Role of the gut microbiota in tumorigenesis and treatment Qingya Liu, Yun Yang, Meng Pan, Fan Yang, Yan Yu, Zhiyong Qian Theranostics 2024; 14(6): 2304-2328. doi:10.7150/thno.91700 Full text PDF PubMed PMC

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Transglutaminase 2 in diabetes mellitus: Unraveling its multifaceted role and therapeutic implications for vascular complications Kwon-Soo Ha Theranostics 2024; 14(6): 2329-2344. doi:10.7150/thno.95742 Full text PDF PubMed PMC

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Theranostics and artificial intelligence: new frontiers in personalized medicine Gokce Belge Bilgin, Cem Bilgin, Brian J. Burkett, Jacob J. Orme, Daniel S. Childs, Matthew P. Thorpe, Thorvardur R Halfdanarson, Geoffrey B Johnson, Ayse Tuba Kendi, Oliver Sartor Theranostics 2024; 14(6): 2367-2378. doi:10.7150/thno.94788 Full text PDF PubMed PMC

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From molecules to medicine: thiol selective bioconjugation in synthesis of diagnostic and therapeutic radiopharmaceuticals Iqra Bibi, Sajid Mushtaq, Kyo Chul Lee, Ji Ae Park, Jung Young Kim Theranostics 2024; 14(6): 2396-2426. doi:10.7150/thno.95469 Full text PDF PubMed PMC

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Theranostics - a sure cure for cancer after 100 years? Yangmeihui Song, Jianhua Zou, E. Alejandro Castellanos, Naomi Matsuura, John A. Ronald, Adam Shuhendler, Wolfgang A Weber, Assaf A. Gilad, Cristina Müller, Timothy H. Witney, Xiaoyuan Chen Theranostics 2024; 14(6): 2464-2488. doi:10.7150/thno.96675 Full text PDF PubMed PMC

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Nanotechnology in inflammation: cutting-edge advances in diagnostics, therapeutics and theranostics Yuting Liu, Ziqi Lin, Yuting Wang, Liuhui Chen, Yuequan Wang, Cong Luo Theranostics 2024; 14(6): 2490-2525. doi:10.7150/thno.91394 Full text PDF PubMed PMC

Retraction

Retraction of “Universal theranostic CRISPR/Cas13a RNA-editing system for glioma” Ye Wu, Yunfei Wang, Junhu Zhou, Jianhao Wang, Qi Zhan, Qixue Wang, Eryan Yang, Weili Jin, Fei Tong, Jixing Zhao, Biao Hong, Junrui Liu, Chunsheng Kang Theranostics 2024; 14(6): 2489. doi:10.7150/thno.96658 Full text PDF PubMed PMC

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