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Volume 14 (5); 2024

Research Papers

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In vivo high-speed microscopy of microbubbles in the chorioallantoic membrane model Rojin Anbarafshan, Carly Pellow, Kevin Kiezun, Hon Leong, David E. Goertz Theranostics 2024; 14(5): 1794-1814. doi:10.7150/thno.91232 Full text PDF PubMed PMC


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Precision peptide theranostics: developing N- to C-terminus optimized theranostics targeting cholecystokinin-2 receptor Marwa N. Rahimi, Alicia Corlett, Jessica Van Zuylekom, Marc Antoine Sani, Benjamin Blyth, Philip Thompson, Peter D. Roselt, Mohammad B. Haskali Theranostics 2024; 14(5): 1815-1828. doi:10.7150/thno.89701 Full text PDF PubMed PMC


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[161Tb]Tb-PSMA-617 radioligand therapy in patients with mCRPC: preliminary dosimetry results and intra-individual head-to-head comparison to [177Lu]Lu-PSMA-617 Andrea Schaefer-Schuler, Caroline Burgard, Arne Blickle, Stephan Maus, Christine Petrescu, Sven Petto, Mark Bartholomä, Tobias Stemler, Samer Ezziddin, Florian Rosar Theranostics 2024; 14(5): 1829-1840. doi:10.7150/thno.92273 Full text PDF PubMed PMC


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Dual regulation of NEMO by Nrf2 and miR-125a inhibits ferroptosis and protects liver from endoplasmic reticulum stress-induced injury Jihoon Tak, Min Sung Joo, Yun Seok Kim, Hyun Woo Park, Chang Hoon Lee, Gil-Chun Park, Shin Hwang, Sang Geon Kim Theranostics 2024; 14(5): 1841-1859. doi:10.7150/thno.89703 Full text PDF PubMed PMC


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Site-specific albumin tagging with NIR-II fluorogenic dye for high-performance and super-stable bioimaging Ningning Zhu, Jiajun Xu, Qi Su, Tianyang Han, Ding Zhou, Yuewei Zhang, Shoujun Zhu Theranostics 2024; 14(5): 1860-1872. doi:10.7150/thno.88815 Full text PDF PubMed PMC


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Cancer-associated fibroblast spatial heterogeneity and EMILIN1 expression in the tumor microenvironment modulate TGF-β activity and CD8+ T-cell infiltration in breast cancer Chikako Kanno Honda, Sasagu Kurozumi, Takaaki Fujii, Didier Pourquier, Lakhdar Khellaf, Florence Boissiere, Jun Horiguchi, Tetsunari Oyama, Ken Shirabe, Jacques Colinge, Takehiko Yokobori, Andrei Turtoi Theranostics 2024; 14(5): 1873-1885. doi:10.7150/thno.90627 Full text PDF PubMed PMC


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Fibroblasts facilitate lymphatic vessel formation in transplanted heart Hui Gong, Ting Wang, Xiaotong Sun, Yuesheng Zhang, Yichao Qiu, Wenlong Sun, Yue Zhang, Peng Teng, Yanhua Hu, Xiaosheng Hu, Liang Ma, Qingbo Xu, Haige Zhao Theranostics 2024; 14(5): 1886-1908. doi:10.7150/thno.92103 Full text PDF PubMed PMC


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Neutrophil extracellular trap-mediated impairment of meningeal lymphatic drainage exacerbates secondary hydrocephalus after intraventricular hemorrhage Qiang Zhang, Yujie Chen, Yingpei Li, Zhou Feng, Liang Liang, Xiaoke Hao, Wenbo Kang, Zhaoqi Zhang, Xuyang Zhang, Rong Hu, Hua Feng, Zhi Chen Theranostics 2024; 14(5): 1909-1938. doi:10.7150/thno.91653 Full text PDF PubMed PMC


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Multifunctional Sr/Se co-doped ZIF-8 nanozyme for chemo/chemodynamic synergistic tumor therapy via apoptosis and ferroptosis Aimin Wu, Ming Han, Zihan Ni, Haoran Li, Yinyin Chen, Zhouping Yang, Yumei Feng, Zufeng He, Hua Zhen, Xianxiang Wang Theranostics 2024; 14(5): 1939-1955. doi:10.7150/thno.92663 Full text PDF PubMed PMC


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H-ferritin-nanocaged gadolinium nanoparticles for ultra-sensitive MR molecular imaging Jianlin Zhang, Chang Yuan, Lingfei Kong, Feiyan Zhu, Wanzhong Yuan, Junying Zhang, Juanji Hong, Fang Deng, Qi Chen, Chen Chen, Tao Wang, Zhentao Zuo, Minmin Liang Theranostics 2024; 14(5): 1956-1965. doi:10.7150/thno.93856 Full text PDF PubMed PMC


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Depletion of ApoA5 aggravates spontaneous and diet-induced nonalcoholic fatty liver disease by reducing hepatic NR1D1 in hamsters Jiabao Guo, Guolin Miao, Wenxi Zhang, Haozhe Shi, Pingping Lai, Yitong Xu, Lianxin Zhang, Gonglie Chen, Yufei Han, Ying Zhao, Geroge Liu, Ling Zhang, Yuhui Wang, Wei Huang, Xunde Xian Theranostics 2024; 14(5): 2036-2057. doi:10.7150/thno.91084 Full text PDF PubMed PMC


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NPC1 is required for postnatal islet β cell differentiation by maintaining mitochondria turnover Bei Liu, Duanyi Hua, Linyan Shen, Tingting Li, Zheying Tao, Chenyang Fu, Zhongzheng Tang, Jie Yang, Li Zhang, Aifang Nie, Yiran Jiang, Jiqiu Wang, Yang Li, Yanyun Gu, Guang Ning Theranostics 2024; 14(5): 2058-2074. doi:10.7150/thno.90946 Full text PDF PubMed PMC


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An advanced comprehensive muti-cell-type-specific model for predicting anti-PD-1 therapeutic effect in melanoma Wei Sun, Yu Zhu, Zijian Zou, Lu Wang, Jingqin Zhong, Kangjie Shen, Xinyi Lin, Zixu Gao, Wanlin Liu, Yinlam Li, Yu Xu, Ming Ren, Tu Hu, Chuanyuan Wei, Jianying Gu, Yong Chen Theranostics 2024; 14(5): 2127-2150. doi:10.7150/thno.91626 Full text PDF PubMed PMC


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FSH induces EMT in ovarian cancer via ALKBH5-regulated Snail m6A demethylation Xingyan Xu, Xuefen Zhuang, Haowei Yu, Ping Li, Xiaosa Li, Huiping Lin, Jian-peng Teoh, Yiwen Chen, Yuanlan Yang, Yang Cheng, Weiyu Chen, Xiaodong Fu Theranostics 2024; 14(5): 2151-2166. doi:10.7150/thno.94161 Full text PDF PubMed PMC


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Immunotherapeutic IL-6R and targeting the MCT-1/IL-6/CXCL7/PD-L1 circuit prevent relapse and metastasis of triple-negative breast cancer Aushia Tanzih Al Haq, Pao-Pao Yang, Christopher Jin, Jou-Ho Shih, Li-Mei Chen, Hong-Yu Tseng, Yen-An Chen, Yueh-Shan Weng, Lu-Hai Wang, Michael P. Snyder, Hsin-Ling Hsu Theranostics 2024; 14(5): 2167-2189. doi:10.7150/thno.92922 Full text PDF PubMed PMC


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G protein subunit alpha i2's pivotal role in angiogenesis Chao-wen Bai, Lu Lu, Jia-nan Zhang, Chengyu Zhou, Yi-chao Ni, Ke-ran Li, Jin Yao, Xiao-zhong Zhou, Chang-gong Lan, Cong Cao Theranostics 2024; 14(5): 2190-2209. doi:10.7150/thno.92909 Full text PDF PubMed PMC


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Intravital imaging of splenic classical monocytes modifying the hepatic CX3CR1+ cells motility to exacerbate liver fibrosis via spleen-liver axis Chenlu Han, Yujie Zhai, Yuke Wang, Xuwen Peng, Xian Zhang, Bolei Dai, Yuehong Leng, Zhihong Zhang, Shuhong Qi Theranostics 2024; 14(5): 2210-2231. doi:10.7150/thno.87791 Full text PDF PubMed PMC


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Dynamic pathological analysis reveals a protective role against skin fibrosis for TREM2-dependent macrophages Yunsheng Liang, Yongfei Hu, Jun Zhang, Haosen Song, Xiaoqian Zhang, Yishan Chen, Yu Peng, Lihua Sun, Yuzhe Sun, Ruzeng Xue, Suyun Ji, Chuanwei Li, Zhili Rong, Bin Yang, Yingping Xu Theranostics 2024; 14(5): 2232-2245. doi:10.7150/thno.94121 Full text PDF PubMed PMC


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Myocardin reverses insulin resistance and ameliorates cardiomyopathy by increasing IRS-1 expression in a murine model of lipodystrophy caused by adipose deficiency of vacuolar H+-ATPase V0d1 subunit Wenlin Yuan, Hui Lin, Yuan Sun, Lihuan Liu, Meijuan Yan, Yujuan Song, Xiaofan Zhang, Xiangling Lu, Yipei Xu, Qiyue He, Kunfu Ouyang, Chenglin Zhang, Yong Pan, Yu Huang, Ying Li, Xifeng Lu, Jie Liu Theranostics 2024; 14(5): 2246-2264. doi:10.7150/thno.93192 Full text PDF PubMed PMC

Reviews

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Cancer diagnosis using label-free SERS-based exosome analysis Yajuan Liu, Mei Li, Haisha Liu, Chao Kang, Cheng Wang Theranostics 2024; 14(5): 1966-1981. doi:10.7150/thno.92621 Full text PDF PubMed PMC


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Highly oriented hydrogels for tissue regeneration: design strategies, cellular mechanisms, and biomedical applications Jiuping Wu, Zhihe Yun, Wenlong Song, Tao Yu, Wu Xue, Qinyi Liu, Xinzhi Sun Theranostics 2024; 14(5): 1982-2035. doi:10.7150/thno.89493 Full text PDF PubMed PMC


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Unleashing the potential of adipose organoids: A revolutionary approach to combat obesity-related metabolic diseases Xingran Liu, Jing Yang, Yuxin Yan, Qingfeng Li, Ru-Lin Huang Theranostics 2024; 14(5): 2075-2098. doi:10.7150/thno.93919 Full text PDF PubMed PMC


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Engineered exosomes and composite biomaterials for tissue regeneration Weikang Hu, Wang Wang, Zesheng Chen, Yun Chen, Zijian Wang Theranostics 2024; 14(5): 2099-2126. doi:10.7150/thno.93088 Full text PDF PubMed PMC


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Extracellular vesicles as carriers of mRNA: Opportunities and challenges in diagnosis and treatment Robert D. Kirian, Darby Steinman, Christopher M. Jewell, Hannah C. Zierden Theranostics 2024; 14(5): 2265-2289. doi:10.7150/thno.93115 Full text PDF PubMed PMC

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