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Review Mechano-immune interactions in musculoskeletal aging: Mechanisms and translational perspectives Fulin Zhou, Xianglong Zhou, Jiheng Xiao, Jianhui Xiang, Yang Liu, Weicheng Chen, Hanhong Fang, Haoran Zhou, Xiao Lv, Liming Xiong Theranostics 2026; 16(13): 7735-7764. doi:10.7150/thno.131071 Full text PDF


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Review Understanding immune checkpoint inhibitors-related myocarditis: Mechanisms and targeted therapeutic pathways Wenxiao Xia, Huan Zhang, Libo Liu, Chenchen Tu, Xiantao Song Theranostics 2026; 16(13): 7715-7734. doi:10.7150/thno.127500 Full text PDF


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Research Paper Ultra-high-field magnetic resonance imaging reveals sex-specific recovery after ischemic stroke following treatment with three-dimensional human mesenchymal stem cell–derived extracellular vesicles Jamini Bhagu, Arshia Arbabian, Thurston Da Vitoria Lobo, Katherine Martinez, Dayna L. Richter, Hannah Bryant, Malathy Elumalai, Yan Li, Samuel C. Grant Theranostics 2026; 16(13): 7698-7714. doi:10.7150/thno.129188 Full text PDF


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Review Cellular senescence in musculoskeletal diseases: biological mechanisms and clinical implications Bingfei Li, Wanwan Qi, Bin Zhang, Shuo Ma, Wei Zhang, Caihua Zhang, Wei Xiang, Ran Chen, Chuanqing Bai, Jun Fei, Changyue Gao, Zhenhong Ni, Siru Zhou Theranostics 2026; 16(13): 7660-7697. doi:10.7150/thno.130018 Full text PDF


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Research Paper A robust asymmetric bioadhesive patch for sutureless intestinal repair to prevent anastomotic leakage and postoperative adhesion Ruiqi Gao, Fangfang Su, Xiaohua Li, Zhongjie He, Yanglin Pan, Yaping Zheng, Mingzhong Wang, Lijun Yuan, Jiahe Liang, Xiaoqian Li Theranostics 2026; 16(13): 7641-7659. doi:10.7150/thno.135611 Full text PDF


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Research Paper Peripheral blood immune profiling reveals key signatures in newly diagnosed NK/T cell lymphoma patients Dahui Li, Hongyuan Zou, Mingyu Wang, Na Tian, Chuanxu Liu, Wenhao Zhang, Shiyu Jiang, Ruiliang Zhu, Xiangyu Yang, Fangxia Li, Ying Gao, Wendi Wei, Ran Jia, Zihan Jiang, Yuanhua Liu, Rong Tao, Xiaozhen Liang Theranostics 2026; 16(13): 7626-7640. doi:10.7150/thno.132582 Full text PDF

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Issue 10; 2026

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Founding Editor-in-Chief:
Prof. Xiaoyuan (Shawn) Chen, PhD
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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.



Ultra-high-field magnetic resonance imaging reveals sex-specific recovery after ischemic stroke following treatment with three-dimensional human mesenchymal stem cell–derived extracellular vesicles

Rationale: Ischemic stroke is sexually dimorphic. Biological sex can influence injury progression and response to treatment. Extracellular vesicles (EV) derived from three-dimensional (3D) human mesenchymal stem cell aggregates (3D-EV) are a promising candidate as a treatment, but their efficacy across these biological variables and in vivo behavior needs to be characterized. This study evaluated whether 3D-EV therapy enhances recovery following ischemic ...

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