Review Mechano-immune interactions in musculoskeletal aging: Mechanisms and translational perspectives Full text PDF
Review Understanding immune checkpoint inhibitors-related myocarditis: Mechanisms and targeted therapeutic pathways Full text PDF
Research Paper Ultra-high-field magnetic resonance imaging reveals sex-specific recovery after ischemic stroke following treatment with three-dimensional human mesenchymal stem cell–derived extracellular vesicles Full text PDF
Review Cellular senescence in musculoskeletal diseases: biological mechanisms and clinical implications Full text PDF
Research Paper A robust asymmetric bioadhesive patch for sutureless intestinal repair to prevent anastomotic leakage and postoperative adhesion Full text PDF
Research Paper Peripheral blood immune profiling reveals key signatures in newly diagnosed NK/T cell lymphoma patients Full text PDF
Issue 10; 2026
Founding Editor-in-Chief:
Prof. Xiaoyuan (Shawn) Chen, PhD
Profile
Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.
Cellular senescence in musculoskeletal diseases: biological mechanisms and clinical implications
Cellular senescence is a persistent state of irreversible growth arrest that occurs when cells encounter various stress signals. It is marked by elevated expression of cell cycle inhibitors, dysregulated gene transcription, and secretion of the senescence-associated secretory phenotype (SASP). These senescent features may exert both detrimental and beneficial effects on tissue homeostasis and systemic physiological integrity. In this review, the relevant ...